ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 10.1.1

Subclass Accession number: 193
Subclass: 10.1.1
Type: HH alpha-alpha
DB: ArchDB-KI

Number of loops: 7

Average sequence ID (%) : 56.3 +/- 3.9
Average RMSD (Å) : 0.88 +/- 0.38

Consensus geometry

d (Å): 21

delta (°): 90-135

theta (°): 90-135

rho (°): 315-360

Consensus Sequence:	XpXhXXPYXGhXXp
(φψ)-conformation:	aalgppplpgbpaa

Pattern:	{IT}	[KQS]	[S]	[D]	[MV]	[W]	[S]	[F]	[G]	[IV]	[LV]	[L]	[TW]	[E]	[IL]	[FTV]	[ST]	{KL}	[AG]	{ER}	x	[P]	[Y]	{P}	[G]	[LMV]	{PST}	{N}	{ER}	[EQ]	[LV]	[FIL]	[DKQ]	x	[LV]	[EKM]
Conservation:	-1.153	-0.581	0.339	1.189	-0.194	3.316	0.339	1.189	1.189	0.128	-0.248	0.339	0.050	0.764	-0.040	-0.893	-0.074	-1.190	-0.095	-0.963	-1.229	1.615	1.615	-0.061	1.189	-0.339	-1.097	-0.661	-0.792	0.177	-0.243	-0.490	-0.586	-1.389	-0.299	-0.823

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1fgk_A_679	1fgk	A	679	714	HQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK	HHHHHHHHHHHHHHHHTTS--SSTT--HHHHHHHHH	aaaaaaaaaaaaaaaaalvxx-lxvxxaaaaaaaaa
1ir3_A_1188	1ir3	A	1188	1223	TSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVM	HHHHHHHHHHHHHHHHHTS--TTTTS-HHHHHHHHH	aaaaaaaaaaaaaaaaalvxx-lpgbxaaaaaaaaa
1irk_*_1188	1irk	-	1188	1223	TSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVM	HHHHHHHHHHHHHHHHHTS--TTTTS-HHHHHHHHH	aaaaaaaaaaaaaaaaalvxx-laabxaaaaaaaaa
2fgi_A_679	2fgi	A	679	714	HQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK	HHHHHHHHHHHHHHHHTTS--SSTT--HHHHHHHHH	aaaaaaaaaaaaaaaaalvxxxlxvxxaaaaaaaaa
2ptk_*_441	2ptk	-	441	476	IKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE	HHHHHHHHHHHHHHHHTTT--SSTT--HHHHHHHHH	aaaaaaaaaaaaaaaaalgpxplxNxbaaaaaaaaa
2src_*_441	2src	-	441	476	IKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE	HHHHHHHHHHHHHHHTTTT--SSTT--HHHHHHHHH	aaaaaaaaaaaaaaaaalvxxplaabxaaaaaaaaa
3lck_*_419	3lck	-	419	454	IKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLE	HHHHHHHHHHHHHHHHTTS--SSTT--HHHHHHHHH	aaaNaaeaaaaaaaaaalveExlpvbxaaaabNaaa

Bibliographic annotations

Loop	PDB	Chain	Annotation	Residue
1ir3_A_1188	1ir3 RefS.R.HUBBARD. CRYSTAL STRUCTURE OF THE ACTIVATED INSULIN RECEPTOR TYROSINE KINASE IN COMPLEX WITH PEPTIDE SUBSTRATE AND ATP ANALOG EMBO J. v.16;5572,1997	A	SUBSTRATE BINDING RESIDUE	N - 1215
1ir3_A_1188	1ir3 RefS.R.HUBBARD. CRYSTAL STRUCTURE OF THE ACTIVATED INSULIN RECEPTOR TYROSINE KINASE IN COMPLEX WITH PEPTIDE SUBSTRATE AND ATP ANALOG EMBO J. v.16;5572,1997	A	SUBSTRATE BINDING RESIDUE	E - 1216
1ir3_A_1188	1ir3 RefS.R.HUBBARD. CRYSTAL STRUCTURE OF THE ACTIVATED INSULIN RECEPTOR TYROSINE KINASE IN COMPLEX WITH PEPTIDE SUBSTRATE AND ATP ANALOG EMBO J. v.16;5572,1997	A	SUBSTRATE BINDING RESIDUE	L - 1219

Clusters included in this Subclass