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Information on SUBCLASS 2.1.35
Subclass Accession number: 2194
Subclass: 2.1.35 PSSM
Type: HH alpha-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 2.7 (>75 %)  2.7.1 (>75 %)  2.7.1.37
GO : GO:0004672 (>75 %)  GO:0005524 (>75 %)  GO:0008047 (>50 %)  GO:0016301 (>75 %)  GO:0016772 (>75 %)  GO:0016773 (>75 %)  GO:0030554 (>75 %)  
SCOP : 56111 (>75 %)  56112 (>75 %)  88854 (>75 %)  
 Number of loops: 3

Average sequence ID (%) : 1.8 +/- 3.7
Average RMSD (Å) : 0.667 +/- 0.058

Consensus geometry
d (Å): 13 delta (°): 0-45 theta (°): 135-180 rho (°): 90-135
Consensus Sequence: ppXcpX
(φψ)-conformation: aappaa
Pattern: xx[DEY][FLT][AKQ][EFM][FIY]x[HKN]x[FI][NRT][NQR]x[DKN][NTY][IPT][KNS]x
Conservation:-0.940-0.8080.119-0.2790.119-0.6761.310-0.9401.045-1.8672.2340.3830.913-0.9400.780-0.146-0.6760.780-0.411
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1ih7_A_7571ih7   A761779QEYFKEFEKEFRQLNYISIHHHHHHHHHHGGGS-HHHHaaaaaaaaaaaaaxxaaaa
1m2o_A_6031m2o   A603621PDETAFYRHIFTREDTTNSHHHHHHHHHHHTTS-HHHHaaaaaaaaaaaaaxxaaaa
1m48_A_61m48   A1836LLDLQMILNGINNYKNPKLHHHHHHHHHHHTT--HHHHaaaaaaaaaaaaaxxaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1m48_A_61m48   A     FRG2-[3-METHYL-4-(N-METHYL-GUANIDINO)-BUTYRYLAMINO]-3-(4-PHENYLETHYNYL-PHENYL)-PROPIONIC ACID METHYL ESTER P - 34
1m48_A_61m48   A     FRG2-[3-METHYL-4-(N-METHYL-GUANIDINO)-BUTYRYLAMINO]-3-(4-PHENYLETHYNYL-PHENYL)-PROPIONIC ACID METHYL ESTER K - 35
1m48_A_61m48   A     FRG2-[3-METHYL-4-(N-METHYL-GUANIDINO)-BUTYRYLAMINO]-3-(4-PHENYLETHYNYL-PHENYL)-PROPIONIC ACID METHYL ESTER L - 36
1m48_A_61m48   A     FRG2-[3-METHYL-4-(N-METHYL-GUANIDINO)-BUTYRYLAMINO]-3-(4-PHENYLETHYNYL-PHENYL)-PROPIONIC ACID METHYL ESTER R - 38
1m48_A_61m48   A     FRG2-[3-METHYL-4-(N-METHYL-GUANIDINO)-BUTYRYLAMINO]-3-(4-PHENYLETHYNYL-PHENYL)-PROPIONIC ACID METHYL ESTER M - 39

Clusters included in this Subclass
CLUSTER: HH.4.216