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PDB code:

Information on SUBCLASS 2.2.7

Subclass Accession number: 2213 Subclass: 2.2.7 Type: HH alpha-alpha DB: ArchDB40 Image coordinates: Consensus coordinates: Conserved Annotation GO : GO:0016773 (>75 %)  GO:0046914 (>75 %)   SCOP : 47239 (>50 %)  47240 (>50 %)  47241 (>75 %)

Number of loops: 12 Average sequence ID (%) : 16.0 +/- 16.1 Average RMSD (Å) : 0.500 +/- 0.160 Consensus geometry d (Å): 5 delta (°): 90-135 theta (°): 135-180 rho (°): 135-180

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1afr_A_185	1afr	A	197	232	RATFISHGNTARQAKEHGDIKLAQICGTIAADEKRH	HHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaavbaaaaaaaaaaaaaaaaa
1bgf_*_50	1bgf	-	58	93	QNLLIQLDEQLGRVSKEKNLLLIHNLKRIRKVLQGK	HHHHHHHHHHHHHHHHHT-HHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaalxaaaaaaaaaaaaaaaaa
1j30_A_8	1j30	A	21	56	SMANRRYLYFAKRADEEGYPEIAGLLRSIAEGETAH	HHHHHHHHHHHHHHHHHT-HHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaavbaaaaaaaaaaaaaaaaa
1jig_A_91	1jig	A	103	138	SALIQELKEGMEVAGEAGDATSADMLLAIHTTLEQH	HHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaavbaaaaaaaaaaaaaaaaa
1moj_A_115	1moj	A	127	162	GDIIEATREHTELAENLGDHATAHMLREGLIELEDD	HHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaavxaaaaaaaaaaaaaaaaa
1nf4_A_88	1nf4	A	100	135	DATIEAYSQFLKVCKEQGDIVTARLFERIIEEEQAH	HHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaalbaaaaaaaaaaaaaaaaa
1nnq_A_6	1nnq	A	20	55	SMAHMRYLIFAEKAEQEGFPNIAKLFRAIAYAEFVH	HHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaavbaaaaaaaaaaaaaaaaa
1o9r_A_103	1o9r	A	115	150	GEVANMIRKAIDDSDEAGDPTTADIFTAASRDLDKS	HHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaavbaaaaaaaaaaaaaaaaa
1pie_A_274	1pie	A	283	318	AVYENNRTKIAQKAFVAGNLTKFGELLNASHASLKD	HHHHHHHHHHHHHHHHHT-HHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaavxaaaaaaaaaaaaaaaaa
1umn_A_111	1umn	A	123	158	RYLAALFQKGFDVSDEEGDSVTNDIFNVAKASIEKH	HHHHHHHHHHHHHHHHHT-HHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaavxaaaaaaaaaaaaaaaaa
1us7_B_184	1us7	B	184	219	EETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFI	HHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaavxaaaaaaaaaaaaaaaaa
2e2a_A_3	2e2a	A	17	52	AGDARSKLLEALKAAENGDFAKADSLVVEAGSCIAE	HHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaavxaaaaaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1afr_A_185	1afr	A	FE2FE (II) ION	E - 196
1afr_A_185	1afr	A	FE2FE (II) ION	T - 199
1afr_A_185	1afr	A	FE2FE (II) ION	H - 203
1afr_A_185	1afr	A	FE2FE (II) ION	I - 225
1afr_A_185	1afr	A	FE2FE (II) ION	D - 228
1afr_A_185	1afr	A	FE2FE (II) ION	E - 229
1afr_A_185	1afr	A	FE2FE (II) ION	H - 232
1j30_A_8	1j30	A	O2OXYGEN MOLECULE	G - 19
1j30_A_8	1j30	A	FEFE (III) ION	E - 20
1j30_A_8	1j30	A	ZNZINC ION	E - 20
1j30_A_8	1j30	A	O2OXYGEN MOLECULE	E - 20
1j30_A_8	1j30	A	FEFE (III) ION	A - 23
1j30_A_8	1j30	A	ZNZINC ION	A - 23
1j30_A_8	1j30	A	O2OXYGEN MOLECULE	A - 23
1j30_A_8	1j30	A	ZNZINC ION	Y - 27
1j30_A_8	1j30	A	O2OXYGEN MOLECULE	Y - 27
1j30_A_8	1j30	A	ZNZINC ION	I - 49
1j30_A_8	1j30	A	FEFE (III) ION	G - 52
1j30_A_8	1j30	A	FEFE (III) ION	E - 53
1j30_A_8	1j30	A	ZNZINC ION	E - 53
1j30_A_8	1j30	A	O2OXYGEN MOLECULE	E - 53
1j30_A_8	1j30	A	FEFE (III) ION	H - 56
1j30_A_8	1j30	A	ZNZINC ION	H - 56
1j30_A_8	1j30	A	O2OXYGEN MOLECULE	H - 56
1moj_A_115	1moj	A	FEFE (III) ION	H - 150
1moj_A_115	1moj	A	FEFE (III) ION	E - 154
1moj_A_115	1moj	A	MGMAGNESIUM ION	H - 164
1moj_A_115	1moj	A	MGMAGNESIUM ION	E - 167
1moj_A_115	1moj	A	MGMAGNESIUM ION	H - 168
1nf4_A_88	1nf4	A	FE2FE (II) ION	E - 99
1nf4_A_88	1nf4	A	FE2FE (II) ION	T - 102
1nf4_A_88	1nf4	A	FE2FE (II) ION	Y - 106
1nf4_A_88	1nf4	A	FE2FE (II) ION	I - 128
1nf4_A_88	1nf4	A	FE2FE (II) ION	E - 131
1nf4_A_88	1nf4	A	FE2FE (II) ION	E - 132
1nf4_A_88	1nf4	A	FE2FE (II) ION	H - 135
1nf4_A_88	1nf4	A	FE2FE (II) ION	L - 136
1nf4_A_88	1nf4	A	FE2FE (II) ION	Y - 139
1nnq_A_6	1nnq	A	ZNZINC ION	E - 19
1nnq_A_6	1nnq	A	ZNZINC ION	A - 22
1nnq_A_6	1nnq	A	ZNZINC ION	Y - 26
1nnq_A_6	1nnq	A	ZNZINC ION	I - 48
1nnq_A_6	1nnq	A	ZNZINC ION	A - 51
1nnq_A_6	1nnq	A	ZNZINC ION	E - 52
1nnq_A_6	1nnq	A	ZNZINC ION	H - 55
1o9r_A_103	1o9r	A	TMNTRIS(HYDROXYMETHYL)AMINOMETHANE	D - 138
1o9r_A_103	1o9r	A	TMNTRIS(HYDROXYMETHYL)AMINOMETHANE	T - 141
1o9r_A_103	1o9r	A	TMNTRIS(HYDROXYMETHYL)AMINOMETHANE	A - 142
1o9r_A_103	1o9r	A	TMNTRIS(HYDROXYMETHYL)AMINOMETHANE	R - 145
1o9r_A_103	1o9r	A	FEFE (III) ION	K - 149
1o9r_A_103	1o9r	A	FEFE (III) ION	W - 152
1umn_A_111	1umn	A	EPE4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	E - 112
1umn_A_111	1umn	A	EPE4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	E - 165

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1o9r_A_103	1o9r	A	AC7TMN BINDING SITE FOR CHAIN E	D - 138

Clusters included in this Subclass

CLUSTER: HH.1.70

CLUSTER: HH.2.164

CLUSTER: HH.2.63

CLUSTER: HH.4.245

CLUSTER: HH.4.79

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