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Information on SUBCLASS 3.2.7
Subclass Accession number: 2281
Subclass: 3.2.7 PSSM
Type: HH alpha-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
GO : GO:0003700 (>75 %)  GO:0003707 (>75 %)  GO:0004872 (>75 %)  GO:0004879 (>75 %)  
SCOP : 48507 (>75 %)  48508 (>75 %)  48509 (>75 %)  
 Number of loops: 6

Average sequence ID (%) : 32.8 +/- 22.8
Average RMSD (Å) : 0.483 +/- 0.223

Consensus geometry
d (Å): 13 delta (°): 45-90 theta (°): 90-135 rho (°): 0-45
Consensus Sequence: XLphppp
(φψ)-conformation: aalppaa
Pattern: [ep][AKLMV][FIL][ADEKS][F]x[gkv][gknqs][FIL][cgkl][aeks][L][EKNQ][LM][DHT][DEQ][EST][DE][hily][AGV][IL][FLM]x[AS][AIV][csv][IL]
Conservation:-0.262-0.7740.458-0.6772.804-0.796-1.422-1.0400.251-1.583-0.7931.4400.0750.896-0.4670.698-0.0321.402-0.911-0.4620.9330.150-0.9980.7000.181-0.5300.759
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1fcy_A_3081fcy   A310336LVFAFAGQLLPLEMDDTETGLLSAICLHHHHHHHHHGGG---HHHHHHHHHHHHaaaaaaaaaaaalxxaaaaaaaaaaaa
1ie9_A_3071ie9   A312338PLIKFQVGLKKLNLHEEEHVLLMAICIHHHHHHHHHHTT---HHHHHHHHHHHHaaaaaaaaaaaalxxaaaaaaaaaaaa
1nq7_A_3361nq7   A341367EAFDFAKNLCSLQLTEEEIALFSSAVLHHHHHHHHHHTT---HHHHHHHHHHHHaaaaaaaaaaaalxxaaaaaaaaaaaa
1nrl_A_3221nrl   A322348PMLKFHYMLKKLQLHEEEYVLMQAISLHHHHHHHHHHHT---HHHHHHHHHHHHaaaaaaaaaaaalxxaaaaaaaaaaaa
1osh_A_3661osh   A368394PMFSFYKSIGELKMTQEEYALLTAIVIHHHHHHHHHHTT---HHHHHHHHHHHHaaaaaaaaaaaalxxaaaaaaaaaaaa
2prg_A_3652prg   A366392PKFEFAVKFNALELDDSDLAIFIAVIIHHHHHHHHHHTT---HHHHHHHHHHHHaaaaaaaaaaaalxbaaaaaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1ie9_A_3071ie9   A     VDX5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL L - 309
1ie9_A_3071ie9   A     VDX5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL L - 313
1ie9_A_3071ie9   A     VDX5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL Q - 317
1nq7_A_3361nq7   A     ARL7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC ACID L - 338
1nq7_A_3361nq7   A     ARL7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC ACID V - 339
1nq7_A_3361nq7   A     ARL7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC ACID A - 342
1nq7_A_3361nq7   A     ARL7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC ACID F - 343
1nrl_A_3221nrl   A     SRL[2-(3,5-DI-TERT-BUTYL-4-HYDROXY-PHENYL)-1-(DIETHOXY-PHOSPHORYL)-VINYL]-PHOSPHONIC ACID DIETHLYL ESTER M - 323
1nrl_A_3221nrl   A     SRL[2-(3,5-DI-TERT-BUTYL-4-HYDROXY-PHENYL)-1-(DIETHOXY-PHOSPHORYL)-VINYL]-PHOSPHONIC ACID DIETHLYL ESTER L - 324
1nrl_A_3221nrl   A     SRL[2-(3,5-DI-TERT-BUTYL-4-HYDROXY-PHENYL)-1-(DIETHOXY-PHOSPHORYL)-VINYL]-PHOSPHONIC ACID DIETHLYL ESTER H - 327
1osh_A_3661osh   A     FEXMETHYL 3-[3-(BENZOYL{[4'-(DIMETHYLAMINO)-1,1'-BIPHENYL -4-YL]METHYL}AMINO)PHENYL]PROPANOATE M - 369
1osh_A_3661osh   A     FEXMETHYL 3-[3-(BENZOYL{[4'-(DIMETHYLAMINO)-1,1'-BIPHENYL -4-YL]METHYL}AMINO)PHENYL]PROPANOATE F - 370
1osh_A_3661osh   A     FEXMETHYL 3-[3-(BENZOYL{[4'-(DIMETHYLAMINO)-1,1'-BIPHENYL -4-YL]METHYL}AMINO)PHENYL]PROPANOATE Y - 373
2prg_A_3652prg   A     BRL2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL) K - 367

Clusters included in this Subclass
CLUSTER: HH.5.71
CLUSTER: HH.6.31