ArchDB - Biological DataBase of Protein Loops

Grup de Recerca en Informàtica Biomèdica

Information on SUBCLASS 3.5.4

Subclass Accession number: 2322
Subclass: 3.5.4

PSSM

Type: HH alpha-alpha
DB: ArchDB40

Image coordinates:

Rasmol PDB

Jmol PDB

Consensus coordinates:

Rasmol PDB

Jmol PDB

Conserved Annotation
GO : GO:0016829 (>75 %) GO:0016830 (>75 %) GO:0016831 (>75 %)
SCOP : 51350 (>75 %) 51366 (>75 %)

Number of loops: 5

Average sequence ID (%) : 13.1 +/- 14.7
Average RMSD (Å) : 0.760 +/- 0.336

Consensus geometry

d (Å): 11

delta (°): 45-90

theta (°): 135-180

rho (°): 135-180

Consensus Sequence:	XphXchp
(φψ)-conformation:	aabapaa

Pattern:	[AGL]	[IKLV]	[HIMVW]	[AGQS]	[ENQRY]	[cv]	[dp]	[DEN]	[ailw]	[ENQY]	[aet]	x	[ekry]	[FKL]	[ksw]	[ILV]
Conservation:	0.108	0.233	-0.708	0.178	-0.166	-0.110	-0.125	2.543	-1.656	0.307	-0.686	-0.242	-0.618	-0.025	-0.872	1.836

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1m0u_A_128	1m0u	A	149	164	AVVSYEPEDEIKEKKL	HHHHT-SSHHHHHHHH	aaaaapaxaaaaaaaa
1mty_B_225	1mty	B	233	248	GLWQEVFDWNESAFSV	HHHHT---HHHHHHHH	aaaaabaxaaaaaaaa
1otv_A_40	1otv	A	63	78	AIMANCPDAQTRRKWV	HHHHT---HHHHHHHH	aaaaabaxaaaaaaaa
1rcw_A_48	1rcw	A	60	75	AIHSRCDDLEARKLLL	HHHTT---HHHHHHHH	aaaaabaxaaaaaaaa
3thi_A_124	3thi	A	124	139	LKIGQVDNIYELYKKI	HHHHT--BHHHHHHHH	aaaaaxabaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1m0u_A_128	1m0u	A	GTTGLUTATHIONE	N - 142
1m0u_A_128	1m0u	A	GTTGLUTATHIONE	R - 145
1rcw_A_48	1rcw	A	MSESELENOMETHIONINE	A - 53
1rcw_A_48	1rcw	A	FEFE (III) ION	F - 54
1rcw_A_48	1rcw	A	MSESELENOMETHIONINE	K - 56
1rcw_A_48	1rcw	A	MSESELENOMETHIONINE	Y - 57
1rcw_A_48	1rcw	A	MSESELENOMETHIONINE	A - 60
1rcw_A_48	1rcw	A	MSESELENOMETHIONINE	S - 63
1rcw_A_48	1rcw	A	MSESELENOMETHIONINE	D - 67
1rcw_A_48	1rcw	A	MSESELENOMETHIONINE	E - 69
1rcw_A_48	1rcw	A	MSESELENOMETHIONINE	A - 70
1rcw_A_48	1rcw	A	MSESELENOMETHIONINE	K - 72
1rcw_A_48	1rcw	A	MSESELENOMETHIONINE	L - 73
1rcw_A_48	1rcw	A	MSESELENOMETHIONINE	L - 74
1rcw_A_48	1rcw	A	MSESELENOMETHIONINE	L - 75
1rcw_A_48	1rcw	A	MSESELENOMETHIONINE	D - 76
1rcw_A_48	1rcw	A	MSESELENOMETHIONINE	N - 77
1rcw_A_48	1rcw	A	FEFE (III) ION	N - 77

Clusters included in this Subclass

CLUSTER: HH.4.117

CLUSTER: HH.5.90