ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 4.39.1

Subclass Accession number: 2429
Subclass: 4.39.1

Type: HH alpha-alpha
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : - (>50 %)  2.7.1 (>75 %)  3.4 (>75 %)  3.4.17 (>75 %)
GO : GO:0004180 (>75 %)  GO:0004672 (>75 %)  GO:0005515 (>75 %)  GO:0005516 (>75 %)  GO:0008233 (>75 %)  GO:0008235 (>75 %)  GO:0008237 (>75 %)  GO:0008238 (>75 %)  GO:0016301 (>75 %)  GO:0016773 (>75 %)
SCOP : 53162 (>75 %)  53187 (>75 %)  53188 (>50 %)  56111 (>75 %)  56112 (>75 %)  88854 (>75 %)

Number of loops: 3

Average sequence ID (%) : 8.3 +/- 11.1
Average RMSD (Å) : 0.733 +/- 0.208

Consensus geometry

d (Å): 13

delta (°): 90-135

theta (°): 135-180

rho (°): 180-225

Consensus Sequence:	hXcXXXXp
(φψ)-conformation:	aalbpbaa

Pattern:	x	[AG]	[AEF]	[LY]	[ALV]	x	x	[AC]	[DHR]	[AIV]	[HL]	[DG]	x	x	x	[NPR]	[DES]	x	x	[AER]	[FKL]	[FIM]	[EQR]	[EMR]	[AVY]	[KL]	x	[HK]
Conservation:	-0.645	1.278	-1.337	2.024	-0.090	-0.367	-0.783	1.718	0.048	0.464	-0.116	1.810	-0.922	-0.922	-0.506	-0.367	0.880	-1.060	-0.922	-0.367	-1.060	0.602	1.157	-0.506	-0.506	0.003	-1.060	1.556

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1gnl_A_137	1gnl	A	153	180	MAAYAKHADVLGKHENSLDAFMQEALAK	HHHHHHHHHHTT---HHHHHHHHHHHHH	aaaaaaaaaaavbbbaaaaaaaaaaaaa
1ks9_A_261	1ks9	A	261	288	NGFLLRRARAHGIAVPENTRLFEMVKRK	HHHHHHHHHHHT---HHHHHHHHHHHHH	aaaaaaaaaaavbxbaaaaaaaaaaaaa
2sqc_A_41	2sqc	A	43	70	EAEYVLLCHILDRVDRDRMEKIRRYLLH	HHHHHHHHHHTT---HHHHHHHHHHHHH	aaaaaaaaaaalbxxaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1gnl_A_137	1gnl	A	FSOIRON/SULFUR/OXYGEN HYBRID CLUSTER	Y - 156
2sqc_A_41	2sqc	A	C8E(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE	T - 41
2sqc_A_41	2sqc	A	C8E(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE	M - 42

Clusters included in this Subclass