ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 6.11.1

Subclass Accession number: 2497
Subclass: 6.11.1

Type: HH alpha-alpha
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 5.4 (>75 %)  5.4.99 (>75 %)  5.4.99.17
GO : GO:0009975 (>75 %)  GO:0016301 (>75 %)  GO:0016829 (>75 %)  GO:0016853 (>75 %)  GO:0016866 (>75 %)  GO:0051007 (>75 %)
SCOP : 48207 (>75 %)  48239 (>75 %)  48243 (>75 %)

Number of loops: 4

Average sequence ID (%) : 22.9 +/- 19.0
Average RMSD (Å) : 0.775 +/- 0.330

Consensus geometry

d (Å): 13

delta (°): 90-135

theta (°): 135-180

rho (°): 180-225

Consensus Sequence:	XhGhppXXph
(φψ)-conformation:	aagppaapaa

Pattern:	x	[DWY]	[DGTV]	[T]	[AGI]	x	[AV]	[LVY]	x	[AC]	[FL]	[GKR]	x	[AFIV]	[G]	[ILMY]	[DPS]	[ADRT]	[ADR]	[EHW]	[DEKP]	x	[ILM]	x	[KR]	[A]	[GLV]	[DER]	[FWY]	[ILV]	x	[DQRS]
Conservation:	-0.686	-0.413	-1.112	2.147	-0.677	-1.112	0.167	-0.160	-1.112	0.676	0.500	-0.123	-0.419	-0.493	2.807	-0.163	-0.002	-0.906	-0.608	-0.226	-0.287	-1.277	0.530	-0.481	1.319	1.487	-0.898	0.260	1.797	0.575	-0.617	-0.493

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
2sqc_A_310	2sqc	A	311	342	VWDTGLAVLALRAAGLPADHDRLVKAGEWLLD	HHHHHHHHHHHHHTT--TT-HHHHHHHHHHHH	aaaaaaaaaaaaaagxxaapaaaaaaaaaaaa
2sqc_A_446	2sqc	A	446	477	EDVTAHVLECFGSFGYDDAWKVIRRAVEYLKR	HHHHHHHHHHHHTTT--TTSHHHHHHHHHHHH	aaaaaaaaaaaaaavxbaaxaaaaaaaaaaaa
2sqc_A_493	2sqc	A	494	525	LYGTGAVVSALKAVGIDTREPYIQKALDWVEQ	HHHHHHHHHHHHHTT--TTSHHHHHHHHHHHH	aaaaaaaaaaaaaavxxaapaaaaaaaaaaaa
2sqc_A_88	2sqc	A	88	119	LDTTIEAYVALKYIGMSRDEEPMQKALRFIQS	HHHHHHHHHHHHHHT--TTSHHHHHHHHHHHH	aaaaaaaaaaaaaaNxxaaxaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
2sqc_A_310	2sqc	A	C8E(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE	W - 312
2sqc_A_446	2sqc	A	C8E(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE	D - 447
2sqc_A_446	2sqc	A	C8E(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE	V - 448
2sqc_A_446	2sqc	A	C8E(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE	H - 451
2sqc_A_493	2sqc	A	C8E(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE	Y - 495

Clusters included in this Subclass