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Information on SUBCLASS 6.46.1
Subclass Accession number: 3386
Subclass: 6.46.1 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 3.5 (>75 %)  3.5.1 (>75 %)  3.5.1.1
GO : GO:0003677 (>75 %)  GO:0004067 (>75 %)  GO:0005524 (>75 %)  GO:0016462 (>75 %)  GO:0016810 (>75 %)  GO:0016811 (>75 %)  GO:0016817 (>75 %)  GO:0016818 (>75 %)  
SCOP : 52539 (>75 %)  52540 (>75 %)  53773 (>75 %)  53774 (>75 %)  53775 (>75 %)  81269 (>75 %)  
 Number of loops: 4

Average sequence ID (%) : 23.8 +/- 19.8
Average RMSD (Å) : 0.575 +/- 0.330

Consensus geometry
d (Å): 15 delta (°): 45-90 theta (°): 135-180 rho (°): 180-225
Consensus Sequence: hDphXpLXXp
(φψ)-conformation: bplaaappaa
Pattern: [FTV][LY][FLV][IL][D][DE][AIV]xx[L][ANS]xxxx[AENS][AKLT][FL][ILY][KRS][ALTV]
Conservation:-0.5120.262-0.0620.8182.9251.3980.062-0.321-0.8061.520-0.029-1.070-0.631-0.675-1.202-0.543-1.0260.464-0.0540.111-0.631
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1fnn_A_1261fnn   A127147FLVLDDAFNLAPDILSTFIRLEEEEETGGGS-HHHHHHHHHHxxbbxlaaaxxaaaaaaaaaa
1in4_A_1051in4   A105125VLFIDEIHRLNKAVEELLYSAEEEEETGGG--HHHHHHHHHHbbxbxlaaaxxaaaaaaaaaa
1njf_A_1211njf   A122142VYLIDEVHMLSRHSFNALLKTEEEEETGGGS-HHHHHHHHHHbbbbxlaaaxxaaaaaaaaaa
1ny5_A_2341ny5   A234254TLFLDEIGELSLEAQAKLLRVEEEEESGGG--HHHHHHHHHHbbbbxvaaaxxaaaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1fnn_A_1261fnn   A     MGMAGNESIUM ION D - 131
1fnn_A_1261fnn   A     ADPADENOSINE-5'-DIPHOSPHATE D - 131
1fnn_A_1261fnn   A     MGMAGNESIUM ION D - 132
1fnn_A_1261fnn   A     ADPADENOSINE-5'-DIPHOSPHATE D - 132
1in4_A_1051in4   A     ADPADENOSINE-5'-DIPHOSPHATE F - 107
1in4_A_1051in4   A     ADPADENOSINE-5'-DIPHOSPHATE D - 109
1njf_A_1211njf   A     ATGPHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER E - 127
1ny5_A_2341ny5   A     ADPADENOSINE-5'-DIPHOSPHATE F - 236
1ny5_A_2341ny5   A     MGMAGNESIUM ION D - 238
1ny5_A_2341ny5   A     ADPADENOSINE-5'-DIPHOSPHATE D - 238
1ny5_A_2341ny5   A     MGMAGNESIUM ION E - 239
1ny5_A_2341ny5   A     PO4PHOSPHATE ION E - 246
1ny5_A_2341ny5   A     PO4PHOSPHATE ION A - 249
1ny5_A_2341ny5   A     PO4PHOSPHATE ION K - 250
1ny5_A_2341ny5   A     PO4PHOSPHATE ION L - 251
1ny5_A_2341ny5   A     PO4PHOSPHATE ION R - 253

Clusters included in this Subclass
CLUSTER: EH.5.224