ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 11.12.1

Subclass Accession number: 3575
Subclass: 11.12.1

Type: EH beta-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 1.1 (>75 %)  1.1.1 (>75 %)  3.1 (>75 %)  3.1.3 (>75 %)  3.1.3.48
GO : GO:0016614 (>75 %)  GO:0016615 (>50 %)  GO:0016616 (>75 %)  GO:0016788 (>75 %)  GO:0016791 (>75 %)  GO:0042578 (>75 %)
SCOP : 51734 (>75 %)  51735 (>75 %)  51848 (>75 %)  52787 (>75 %)  52788 (>75 %)  52789 (>75 %)

Number of loops: 3

Average sequence ID (%) : 43.6 +/- 10.7
Average RMSD (Å) : 0.267 +/- 0.058

Consensus geometry

d (Å): 19

delta (°): 90-135

theta (°): 135-180

rho (°): 0-45

Consensus Sequence:	hhXSchphGpXPDXR
(φψ)-conformation:	bbapaaaplppppaa

Pattern:	[NW]	x	[IV]	[D]	[S]	[AFG]	[AG]	[TV]	[S]	[DGN]	[WY]	[EHN]	[IV]	[G]	[ENR]	[PS]	[P]	[D]	x	[R]	[AGT]	x	[S]	[CI]	[CLM]	[KR]
Conservation:	-0.072	-1.368	0.135	1.547	0.406	-1.495	-0.505	-0.457	0.406	-0.734	1.105	-0.544	0.135	1.547	-0.861	-0.690	2.117	1.547	-0.861	0.977	-1.178	-1.136	0.406	0.137	-0.734	0.167

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1d1q_A_40	1d1q	A	41	66	NKIDSFGTSNYHVGESPDHRTVSICK	EEEEEEESS-TTBT----HHHHHHHH	abbbbbbaxaaapvxxxpaaaaaaaa
1phr_*_39	1phr	-	39	64	WVIDSGAVSDWNVGRSPDPRAVSCLR	EEEEEEESSSTTTT----HHHHHHHH	bbbbbbbaxaaapvxxppaaaaaaaa
5pnt_*_39	5pnt	-	39	64	WRVDSAATSGYEIGNPPDYRGQSCMK	EEEEEEESSSTTTT----HHHHHHHH	bbbbbbbabaaapvxxppaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1d1q_A_40	1d1q	A	4NP4-NITROPHENYL PHOSPHATE	F - 46
1d1q_A_40	1d1q	A	4NP4-NITROPHENYL PHOSPHATE	H - 52
5pnt_*_39	5pnt	*	MES2-(N-MORPHOLINO)-ETHANESULFONIC ACID	Y - 49
5pnt_*_39	5pnt	*	MES2-(N-MORPHOLINO)-ETHANESULFONIC ACID	E - 50

Clusters included in this Subclass