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Information on SUBCLASS 12.5.1
Subclass Accession number: 3582
Subclass: 12.5.1 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 3.1 (>75 %)  3.1 (>75 %)  3.1.3 (>75 %)  3.1.3 (>75 %)  3.1.3.113.1.3.11
GO : GO:0016788 (>75 %)  GO:0016788 (>75 %)  GO:0016791 (>75 %)  GO:0016791 (>75 %)  GO:0042578 (>75 %)  GO:0042578 (>75 %)  
SCOP : 56654 (>75 %)  56654 (>75 %)  56655 (>75 %)  56655 (>75 %)  56656 (>75 %)  56656 (>75 %)  
 Number of loops: 4

Average sequence ID (%) : 76.7 +/- 0.7
Average RMSD (Å) : 0.500 +/- 0.115

Consensus geometry
d (Å): 13 delta (°): 90-135 theta (°): 135-180 rho (°): 180-225
Consensus Sequence: hYPXcKKSXcGKLRLL
(φψ)-conformation: bbppbaabaaeappaa
Pattern: [I][FY][GLM][Y][P][AR][DN][K][K][S][KP][DKN][G][K][L][R][L][L][Y][E][C][AN][P][M][AS][FY][IV][MV][E][KQ]
Conservation:-0.2010.183-2.0271.3961.396-1.410-0.4580.3320.332-0.201-0.945-1.2490.8640.332-0.2010.332-0.201-0.2011.3960.3322.460-1.4771.3960.332-0.9940.180-0.463-0.8390.332-0.726
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1bk4_A_2611bk4   A261290IFLYPANKKSPDGKLRLLYECNPMAFIMEKEEEE---SS-TT-SSBTTTTHHHHHHHHHHbbbbxxbaabaaeaxxaaaIaaaaaaaaaa
1dcu_A_2861dcu   A286315IYGYPRDKKSKNGKLRLLYECAPMSFIVEQEEEE---SSSTT-SSBTTTTHHHHHHHHHHbbbbxxbaabaaeaxxaaaaaaaaaaaaaa
1fta_A_2611fta   A261290IFLYPANKKSPNGKLRLLYECNPMAYVMEKEEEE--BTTBTT-SSBTTTTHHHHHHHHHHbbbbxxbaabaaeaxxaaaaaaaaaaaaaa
1nuy_A_12611nuy   A12611290IFMYPANKKSPKGKLRLLYECNPMAYVMEKEEEE--BTTBTT-SSBTTTTHHHHHHHHHHbbbbwxbaabaaeaxxaaaaaaaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1bk4_A_2611bk4   A     MGMAGNESIUM ION R - 276
1bk4_A_2611bk4   A     MGMAGNESIUM ION Y - 279
1bk4_A_2611bk4   A     MGMAGNESIUM ION E - 280
1nuy_A_12611nuy   A     F6PFRUCTOSE-6-PHOSPHATE F - 1262
1nuy_A_12611nuy   A     F6PFRUCTOSE-6-PHOSPHATE Y - 1264
1nuy_A_12611nuy   A     F6PFRUCTOSE-6-PHOSPHATE K - 1274
1nuy_A_12611nuy   A     PIHYDROGENPHOSPHATE ION K - 1274
1nuy_A_12611nuy   A     F6PFRUCTOSE-6-PHOSPHATE L - 1275
1nuy_A_12611nuy   A     MGMAGNESIUM ION L - 1275
1nuy_A_12611nuy   A     F6PFRUCTOSE-6-PHOSPHATE R - 1276
1nuy_A_12611nuy   A     MGMAGNESIUM ION R - 1276
1nuy_A_12611nuy   A     PIHYDROGENPHOSPHATE ION R - 1276
1nuy_A_12611nuy   A     F6PFRUCTOSE-6-PHOSPHATE E - 1280
1nuy_A_12611nuy   A     MGMAGNESIUM ION E - 1280
1nuy_A_12611nuy   A     PIHYDROGENPHOSPHATE ION E - 1280
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1bk4_A_2611bk4   A MGTHE MG2+ BINDING SITE IS NEAR THE CATALYTIC CLEFT OF THE EN A SULFATE (SO4 328) BINDS AT THE PHOSPHATE BINDING SITE OFE - 280

Clusters included in this Subclass
CLUSTER: EH.15.14