ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 12.9.1

Subclass Accession number: 3586
Subclass: 12.9.1

Type: EH beta-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 4.1 (>50 %)  4.1 (>50 %)  4.1.3 (>50 %)  4.1.3 (>50 %)  4.1.3.3 4.1.3.3
GO : GO:0008747 (>50 %)  GO:0016829 (>75 %)  GO:0016830 (>50 %)  GO:0016833 (>50 %)
SCOP : 51569 (>75 %)  51569 (>75 %)  51570 (>75 %)  51570 (>75 %)

Number of loops: 3

Average sequence ID (%) : 24.1 +/- 17.1
Average RMSD (Å) : 0.400 +/- 0.100

Consensus geometry

d (Å): 17

delta (°): 45-90

theta (°): 135-180

rho (°): 270-315

Consensus Sequence:	XAhhXXhcppXXhXpX
(φψ)-conformation:	ppppbpbpaalpppaa

Pattern:	x	[FIM]	[ASV]	[A]	[IL]	[LV]	[TV]	[PS]	[FM]	[DN]	[EQ]	[DKQ]	[GQ]	[ANT]	[ILV]	[CDN]	[EKR]	[AK]	[GS]	[L]	[KR]	[KQR]	[IL]	[IV]	[DQR]	[FHY]	[HN]	[IV]	[ADQ]
Conservation:	-1.550	-0.741	-1.550	1.454	0.493	0.012	-0.046	0.318	0.513	1.130	1.077	-0.857	-0.371	-1.434	0.068	-1.434	-0.279	-0.812	-0.195	1.454	1.052	-0.048	0.493	0.982	-1.088	0.645	1.404	0.973	-1.665

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1f74_A_6	1f74	A	7	35	IFSALLVSFNEDGTINEKGLRQIIRHNID	EEEE----B-TTS-B-HHHHHHHHHHHHH	xbxxpxbxbxaavxxxaaaaaaaaaaaaa
1hl2_A_8	1hl2	A	8	36	VMAALLTPFDQQQALDKASLRRLVQFNIQ	EEEE----B-TTSSB-HHHHHHHHHHHHH	bbxxxxbxbxaavxpxaaaaaaaaaaaaa
1s5t_A_4	1s5t	A	5	33	SIVAIVTPMDEKGNVCRASLKKLIDYHVA	EEEE----B-TTSSB-HHHHHHHHHHHHH	xbxxxxxxbxaavbpbaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1f74_A_6	1f74	A	NAY6,7,8,9-TETRAHYDROXY-5-METHYLCARBOXAMIDO-2-OXONONANOIC ACID	A - 10
1hl2_A_8	1hl2	A	3PY3-HYDROXYPYRUVIC ACID	A - 11

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1hl2_A_8	1hl2	A	AC13PY BINDING SITE FOR CHAIN A	A - 11

Clusters included in this Subclass