ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 16.3.1

Subclass Accession number: 3614
Subclass: 16.3.1

Type: EH beta-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 2.6 (>75 %)  2.6.1 (>75 %)  2.6.1.1 5.3 (>75 %)  5.3.1 (>75 %)  5.3.1.1
GO : GO:0004069 (>75 %)  GO:0004807 (>75 %)  GO:0008483 (>75 %)  GO:0016769 (>75 %)  GO:0016853 (>75 %)  GO:0016860 (>75 %)  GO:0016861 (>75 %)
SCOP : 51351 (>75 %)  51352 (>75 %)  53382 (>75 %)  53383 (>75 %)  53384 (>75 %)

Number of loops: 5

Average sequence ID (%) : 57.6 +/- 21.5
Average RMSD (Å) : 0.440 +/- 0.195

Consensus geometry

d (Å): 25

delta (°): 45-90

theta (°): 45-90

rho (°): 0-45

Consensus Sequence:	hNLGhGhYppppGpXhVLXX
(φψ)-conformation:	bbaappbpbpaalbpbppaa

Pattern:	[IMV]	[DN]	[L]	[G]	[IV]	[G]	[AV]	[Y]	[KR]	[DT]	[DE]	[DENT]	[CG]	[KQ]	[PT]	[PWY]	[V]	[L]	[NPT]	[CSV]	[V]	[KR]	[AK]	[AV]	[E]	[AKQ]	[lmy]	[IL]	[al]
Conservation:	-0.319	0.412	0.557	1.819	0.241	1.819	-0.617	2.451	0.308	-0.345	0.560	-0.973	-0.491	0.002	-0.068	-0.589	0.557	0.557	-1.053	-1.432	0.557	0.241	-0.572	-0.629	1.188	-0.974	-1.511	-0.030	-1.664

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1ajs_A_33	1ajs	A	33	61	VNLGVGAYRTDDCQPWVLPVVRKVEQRIA	EE--S-----TTS-----HHHHHHHHHHH	bxaFpxbxbxaavbxbxpaaaaaaaaaaa
1qis_A_33	1qis	A	33	61	INLGIGVYKDETGKTPVLTSVKKAEQYLL	EE--S-----TTS-----HHHHHHHHHHH	bbaaxxbxbxaavbbxxpaaaaaaaaaaa
1yaa_A_33	1yaa	A	33	61	VDLGIGAYRDDNGKPWVLPSVKAAEKLIH	EE-SS---B-TTS-B---HHHHHHHHHHH	bbaFxxbpbxaavbpbxpaaaaaaaaaaa
2cst_A_33	2cst	A	33	61	VNLGVGAYRTDEGQPWVLPVVRKVEQLIA	EE--SS----TTS-----HHHHHHHHHHH	bbaapxbxbxaavbxbxpaaaaaaaaaaa
7aat_A_33	7aat	A	33	61	MNLGVGAYRDDNGKPYVLNCVRKAEAMIA	EE----S---TTS-----HHHHHHHHHHH	bbaaxabxbxaavbxbxxaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1ajs_A_33	1ajs	A	PLA2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID	G - 36
1ajs_A_33	1ajs	A	PLA2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID	V - 37
1ajs_A_33	1ajs	A	PLA2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID	G - 38
1ajs_A_33	1ajs	A	PLA2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID	A - 39
1qis_A_33	1qis	A	MAEMALEIC ACID	G - 36
1qis_A_33	1qis	A	MAEMALEIC ACID	I - 37
1qis_A_33	1qis	A	PLPPYRIDOXAL-5'-PHOSPHATE	G - 38
1qis_A_33	1qis	A	MAEMALEIC ACID	G - 38
1qis_A_33	1qis	A	MAEMALEIC ACID	V - 39
1yaa_A_33	1yaa	A	MAEMALEIC ACID	A - 39
2cst_A_33	2cst	A	MAEMALEIC ACID	V - 37

Clusters included in this Subclass