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Information on SUBCLASS 19.2.1
Subclass Accession number: 3627
Subclass: 19.2.1 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 3.1 (>75 %)  3.1.1 (>75 %)  3.1.1.33.2 (>75 %)  3.2.1 (>75 %)  3.2.1.1
GO : GO:0004553 (>75 %)  GO:0005509 (>75 %)  GO:0016160 (>75 %)  GO:0016298 (>75 %)  GO:0016788 (>75 %)  GO:0016789 (>75 %)  GO:0016798 (>75 %)  
SCOP : 51445 (>75 %)  51446 (>75 %)  53473 (>75 %)  53474 (>75 %)  53577 (>75 %)  
 Number of loops: 4

Average sequence ID (%) : 61.9 +/- 13.8
Average RMSD (Å) : 0.225 +/- 0.050

Consensus geometry
d (Å): 15 delta (°): 45-90 theta (°): 90-135 rho (°): 135-180
Consensus Sequence: YDhhDLGEhpQKGTVpTphGpKX
(φψ)-conformation: abaabagabpbllbappaaepaa
Pattern: [APV][Y][D][LY][FY][D][L][G][E][FY][NQY][Q][K][G][AT][V][ER][T][KR][FY][G][ST][K][AES][EQ][LY]x[DQR][AL][I][GQ][AST][AL][HK][AS]
Conservation:-1.3571.8971.337-0.8580.7271.3370.2171.3370.7770.619-1.2560.7770.7771.337-0.6180.217-0.5720.777-0.0320.7271.337-0.3940.777-1.213-0.060-0.860-1.814-1.140-1.1320.217-1.049-0.953-1.167-0.100-0.613
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1e43_A_561e43   A5690PYDLYDLGEFQQKGTVRTKYGTKSELQDAIGSLHSEEETT-SS-S-BTTBSS-SS--HHHHHHHHHHHHHxabaabavabxbvvbaxxaaexaaaaaaaaaaaaa
1hvx_A_591hvx   A5993VYDLYDLGEFNQKGAVRTKYGTKAQYLQAIQAAHAEEETT-SS-S-BTTBSS-SS--HHHHHHHHHHHHHxabaabavabxbvvbaxxaaexaaaaaaaaaaaaa
1mxg_A_641mxg   A6498PYDYFDLGEYYQKGTVETRFGSKEELVRLIQTAHAEEETT-SS-S-BTTBSS-SS--HHHHHHHHHHHHHwabaabagabxblvbaxxaaexaaaaaaaaaaaaa
1ud2_A_581ud2   A5892AYDLYDLGEFNQKGTVRTKYGTKAQLERAIGSLKSEEETT-SS-S-BTTBSS-SS--HHHHHHHHHHHHHxabaabavabxblvbaxxaaexaaaaaaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1mxg_A_641mxg   A     ETE2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL F - 68
1mxg_A_641mxg   A     ETE2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL D - 69
1mxg_A_641mxg   A     ETE2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL E - 72
1mxg_A_641mxg   A     ETE2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL Y - 73
1mxg_A_641mxg   A     MGMAGNESIUM ION E - 80
1mxg_A_641mxg   A     MGMAGNESIUM ION F - 83
1mxg_A_641mxg   A     MGMAGNESIUM ION G - 84
1mxg_A_641mxg   A     MGMAGNESIUM ION S - 85
1mxg_A_641mxg   A     ETE2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL K - 86
1mxg_A_641mxg   A     MGMAGNESIUM ION E - 88
1mxg_A_641mxg   A     ETE2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL R - 91
1mxg_A_641mxg   A     ETE2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL T - 95
1mxg_A_641mxg   A     EOHETHANOL T - 95
1mxg_A_641mxg   A     EOHETHANOL A - 98

Clusters included in this Subclass
CLUSTER: EH.18.4