ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 24.1.1

Subclass Accession number: 3633
Subclass: 24.1.1

Type: EH beta-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : - (>75 %)  2 (>75 %)  2 (>75 %)  3 (>75 %)  3 (>75 %)
GO : GO:0016798 (>75 %)  GO:0016799 (>75 %)  GO:0019104 (>75 %)
SCOP : 52140 (>75 %)  52140 (>75 %)  52141 (>75 %)  52141 (>75 %)  52142 (>75 %)  52142 (>75 %)

Number of loops: 4

Average sequence ID (%) : 69.8 +/- 7.2
Average RMSD (Å) : 0.400 +/- 0.082

Consensus geometry

d (Å): 13

delta (°): 45-90

theta (°): 135-180

rho (°): 0-45

Consensus Sequence:	hGQDPYHXPcQAHGLhFSVpXXhhhPPS
(φψ)-conformation:	pbabppapplapagbpgpbppwppppaa

Pattern:	[V]	[V]	[I]	[IL]	[G]	[Q]	[D]	[P]	[Y]	[H]	x	[P]	[GN]	[Q]	[A]	[H]	[G]	[L]	[AC]	[F]	[S]	[V]	[QR]	x	[GNP]	[IV]	[AP]	[IP]	[P]	[P]	[S]	[L]	x	[N]	[IMV]	[LY]	[AK]	[AE]	[LV]	[CEKS]	[NT]	[CDT]
Conservation:	0.006	0.006	0.006	-0.454	0.953	0.479	0.953	1.426	1.426	1.899	-0.724	1.426	-0.446	0.479	0.006	1.899	0.953	0.006	-0.470	0.953	0.006	0.006	-0.453	-1.502	-1.312	-0.222	-0.631	-1.088	1.426	1.426	0.006	0.006	-1.887	0.953	-0.675	-0.663	-0.984	-0.984	-0.684	-1.621	-0.538	-1.370

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1akz_*_139	1akz	-	139	180	VVILGQDPYHGPNQAHGLCFSVQRPVPPPPSLENIYKELSTD	EEEEE-S---STTT--SSTT---TTS---HHHHHHHHHHHHH	bbbxbabwxaxpvaxagbxvxbxpwxxpxaaaaaaaaaaaaa
1lau_E_82	1lau	E	82	123	VVIIGQDPYHHPGQAHGLAFSVRANVPPPPSLRNVLAAVKNC	EEEEE-S---STTT--SSSS---TTS---HHHHHHHHHHHHH	bbbxbabxpabpvaxagbxgxbppvbpxxaaaaaaaaaaaaa
1okb_A_139	1okb	A	139	180	VVILGQDPYHGPNQAHGLCFSVQKPVPPPPSLVNIYKELCTD	EEEEESS---STTT-SSSTT---TTS---HHHHHHHHHHHHH	bbbxbFbxpaxpvaxavbxvxbxxwpxpxaaaaaaaaaaaaa
3eug_A_58	3eug	A	58	99	VVILGQDPYHGPGQAHGLAFSVRPGIAIPPSLLNMYKELENT	EEEEESS---STTT-SSSTT---TTS---HHHHHHHHHHHHH	bbbxbaxxpabxvaxagbpvxbxpvbpxxaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1okb_A_139	1okb	A	GOLGLYCEROL	G - 143
1okb_A_139	1okb	A	GOLGLYCEROL	Q - 144
1okb_A_139	1okb	A	GOLGLYCEROL	D - 145
1okb_A_139	1okb	A	GOLGLYCEROL	P - 146
1okb_A_139	1okb	A	GOLGLYCEROL	Y - 147
1okb_A_139	1okb	A	GOLGLYCEROL	L - 156
1okb_A_139	1okb	A	GOLGLYCEROL	C - 157
1okb_A_139	1okb	A	GOLGLYCEROL	F - 158
1okb_A_139	1okb	A	GOLGLYCEROL	S - 159
1okb_A_139	1okb	A	GOLGLYCEROL	S - 169
3eug_A_58	3eug	A	GOLGLYCEROL	G - 62
3eug_A_58	3eug	A	GOLGLYCEROL	Q - 63
3eug_A_58	3eug	A	GOLGLYCEROL	D - 64
3eug_A_58	3eug	A	GOLGLYCEROL	P - 65
3eug_A_58	3eug	A	GOLGLYCEROL	Y - 66
3eug_A_58	3eug	A	GOLGLYCEROL	L - 75
3eug_A_58	3eug	A	GOLGLYCEROL	A - 76
3eug_A_58	3eug	A	GOLGLYCEROL	F - 77
3eug_A_58	3eug	A	GOLGLYCEROL	S - 78
3eug_A_58	3eug	A	GOLGLYCEROL	S - 88

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1okb_A_139	1okb	A	AC1GOL BINDING SITE FOR CHAIN A	Q - 144
1okb_A_139	1okb	A	AC1GOL BINDING SITE FOR CHAIN A	D - 145
1okb_A_139	1okb	A	AC1GOL BINDING SITE FOR CHAIN A	C - 157
1okb_A_139	1okb	A	AC1GOL BINDING SITE FOR CHAIN A	F - 158
3eug_A_58	3eug	A	URAURACIL BINDING SITE	D - 64

Clusters included in this Subclass

CLUSTER: EH.23.0