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Information on SUBCLASS 5.2.1
Subclass Accession number: 40
Subclass: 5.2.1
Type: EH beta-alpha
DB: ArchDB-KI
 Number of loops: 5

Average sequence ID (%) : 61.6 +/- 4.8
Average RMSD (Å) : 0.45 +/- 0.13

Consensus geometry
d (Å): 11 delta (°): 45-90 theta (°): 135-180 rho (°): 0-45
Consensus Sequence: hNFSHGppE
(φψ)-conformation: bpaabebaa
Pattern: [IV][AMV][R][LM][N][F][S][H][G][DST][HY][AE][EY][H]{AG}[EQS]{TV}[I][DKQ][N][ALV][R]{KNT}{AV}{ET}
Conservation:0.028-0.8850.667-0.0961.1011.1010.2331.9691.101-0.7790.560-0.634-0.4491.969-1.068-0.627-1.1970.233-0.7331.101-0.9160.667-1.178-1.007-1.159
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a3x_A_451a3x   A4771IVRMNFSHGSYEYHKSVIDNARKSEEEEEETTS--HHHHHHHHHHHHHHHbbbbxaabexaaaaaaaaaaaaaaa
1a49_A_701a49   A7094VARMNFSHGTHEYHAETIKNVRTATEEEEETTSS-HHHHHHHHHHHHHHHbbbbxaabebaaaaaaaaaaaaaaa
1pkm_*_681pkm   -7094VARLNFSHGTHEYHAETIKNVRAATEEEEETTSS-HHHHHHHHHHHHHHHbxbbxaabebaaaaaaaaaaaaaaa
1pkn_*_701pkn   -7094VARMNFSHGTHEYHAETIKNVRTATEEEEETTS--HHHHHHHHHHHHHHHbbxbxaabexaaaaaaaaaaaaaaa
1pky_A_281pky   A3054VMRLNFSHGDYAEHGQRIQNLRNVMEEEEETTS--HHHHHHHHHHHHHHHbxbbxaabebaaaaaaaaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1a3x_A_451a3x   A     PGA2-PHOSPHOGLYCOLIC ACID R - 49
1a3x_A_451a3x   A     PGA2-PHOSPHOGLYCOLIC ACID N - 51
1a3x_A_451a3x   A     PGA2-PHOSPHOGLYCOLIC ACID S - 53
1a49_A_701a49   A     OXLOXALATE ION R - 72
1a49_A_701a49   A     MGMAGNESIUM ION R - 72
1a49_A_701a49   A     ATPADENOSINE-5'-TRIPHOSPHATE R - 72
1a49_A_701a49   A     MGMAGNESIUM ION N - 74
1a49_A_701a49   A     ATPADENOSINE-5'-TRIPHOSPHATE N - 74
1a49_A_701a49   A     ATPADENOSINE-5'-TRIPHOSPHATE S - 76
1a49_A_701a49   A     ATPADENOSINE-5'-TRIPHOSPHATE H - 77
1a49_A_701a49   A     ATPADENOSINE-5'-TRIPHOSPHATE G - 78
1a49_A_701a49   A     ATPADENOSINE-5'-TRIPHOSPHATE Y - 82
1a49_A_701a49   A     ATPADENOSINE-5'-TRIPHOSPHATE H - 83
1a49_A_701a49   A     ATPADENOSINE-5'-TRIPHOSPHATE T - 86
1pkn_*_701pkn   *     PYRPYRUVIC ACID R - 72
Bibliographic annotations
LoopPDBChainAnnotationResidue
1a49_A_701a49   RefT.M.LARSEN,M.M.BENNING,I.RAYMENT,G.H.REED. STRUCTURE OF THE BIS(MG2+)-ATP-OXALATE COMPLEX OF THE RABBIT MUSCLE PYRUVATE KINASE AT 2.1 A RESOLUTION: ATP BINDING OVER A BARREL  BIOCHEMISTRY v.37;6247,1998AATP BINDING RESIDUER - 72
1a49_A_701a49   RefT.M.LARSEN,M.M.BENNING,I.RAYMENT,G.H.REED. STRUCTURE OF THE BIS(MG2+)-ATP-OXALATE COMPLEX OF THE RABBIT MUSCLE PYRUVATE KINASE AT 2.1 A RESOLUTION: ATP BINDING OVER A BARREL  BIOCHEMISTRY v.37;6247,1998AATP BINDING RESIDUEN - 74

Clusters included in this Subclass
CLUSTER: EH.4.5
CLUSTER: EH.4.8