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Information on SUBCLASS 6.2.4
Subclass Accession number: 408
Subclass: 6.2.4 PSSM
Type: HE alpha-beta
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 2.5 (>75 %)  2.5.1 (>75 %)  2.5.1.9
GO : GO:0004746 (>75 %)  GO:0016765 (>75 %)  
SCOP : 103088 (>75 %)  103089 (>75 %)  52120 (>75 %)  52121 (>75 %)  52122 (>75 %)  55297 (>75 %)  
 Number of loops: 4

Average sequence ID (%) : 16.7 +/- 16.9
Average RMSD (Å) : 0.550 +/- 0.173

Consensus geometry
d (Å): 11 delta (°): 90-135 theta (°): 135-180 rho (°): 225-270
Consensus Sequence: hXGhphXphX
(φψ)-conformation: aagppaaabb
Pattern: [AV]x[AGKV][AGV][AKV]xx[LTY]x[AGS][AKNQ][G][FIV][DKPS][APV][ADKS][DQR][IL]x[AGIL][GIV]x
Conservation:0.842-1.007-0.819-0.338-0.264-0.161-0.772-0.264-0.6780.592-0.3023.5530.594-0.302-0.096-0.3490.4691.435-0.600-0.866-0.227-0.439
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1kfw_A_3041kfw   A304325ADKAVKKYLAAGIDPKQLGLGLHHHHHHHHHHTT--GGGEEEEEaaaaaaaaaaavxpaaabbbxb
1oap_A_941oap   A105126ANAVKMYLQGKGVSADQISIVSHHHHHHHHHTTT--GGGEEEEEaaaaaaaaaaavxxaaabbbbb
1r1m_A_1251r1m   A136157AYVVANNLVSNGVPVSRISAVGHHHHHHHHHHTT--GGGEEEEEaaaaaaaaaaagxpaaabbbbb
8abp_*_2068abp   -209230VLGGVRATEGQGFKAADIIGIGHHHHHHHHHHTT--GGGEEEEEaaaaaaaaaaavxxaaabbbbx
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1r1m_A_1251r1m   A     TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL Y - 137
1r1m_A_1251r1m   A     TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL A - 140
1r1m_A_1251r1m   A     TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL N - 141
1r1m_A_1251r1m   A     TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL V - 144
1r1m_A_1251r1m   A     TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL V - 150
1r1m_A_1251r1m   A     TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL I - 153
8abp_*_2068abp   *     GLAALPHA D-GALACTOSE I - 231
8abp_*_2068abp   *     GLBBETA-D-GALACTOSE I - 231
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1oap_A_941oap   A AC1SO4 BINDING SITE FOR CHAIN AY - 96
1oap_A_941oap   A AC1SO4 BINDING SITE FOR CHAIN AN - 97
1oap_A_941oap   A AC1SO4 BINDING SITE FOR CHAIN AL - 100
1oap_A_941oap   A AC1SO4 BINDING SITE FOR CHAIN AR - 104

Clusters included in this Subclass
CLUSTER: HE.8.17