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Information on SUBCLASS 7.42.1
Subclass Accession number: 4183
Subclass: 7.42.1 PSSM
Type: AR beta-beta link
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 1.5 (>75 %)  1.5.1 (>75 %)  1.5.1.3
GO : GO:0004146 (>75 %)  GO:0016645 (>75 %)  GO:0016646 (>75 %)  
SCOP : 53596 (>75 %)  53597 (>75 %)  53598 (>75 %)  
 Number of loops: 3

Average sequence ID (%) : 58.3 +/- -3.7
Average RMSD (Å) : 0.267 +/- 0.058

Consensus geometry
d (Å): 15 delta (°): 90-135 theta (°): 90-135 rho (°): 225-270
Consensus Sequence: RhhXpFEXDTX
(φψ)-conformation: bpabbbpbabb
Pattern: [KRT][L][FL][V][T][R][IL][ALM]x[DES][F][E][GS][D][T][FK]
Conservation:-1.0740.298-0.4970.2980.8860.886-0.282-1.204-1.335-0.8121.4740.886-0.6321.4740.886-1.252
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1kmv_A_1311kmv   A132147KLFVTRIMQDFESDTFEEEEEEESS----SEEbbxbxxxabxbpbabb
3dfr_*_1123dfr   -112127TLLVTRLAGSFEGDTKEEEEEEESS----SEEbbbbbbxaxbbxbabb
8dfr_*_1308dfr   -132147RLFVTRILHEFESDTFEEEEEEESS----SEEbbbbbxxabbbxbabb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1kmv_A_1311kmv   A     LII(Z)-6-(2-[2,5-DIMETHOXYPHENYL]ETHEN-1-YL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE F - 134
1kmv_A_1311kmv   A     LII(Z)-6-(2-[2,5-DIMETHOXYPHENYL]ETHEN-1-YL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE T - 136
1kmv_A_1311kmv   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE D - 145
1kmv_A_1311kmv   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE T - 146
3dfr_*_1123dfr   *     MTXMETHOTREXATE L - 114
3dfr_*_1123dfr   *     MTXMETHOTREXATE V - 115
3dfr_*_1123dfr   *     MTXMETHOTREXATE T - 116
3dfr_*_1123dfr   *     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE D - 125
3dfr_*_1123dfr   *     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE T - 126

Clusters included in this Subclass
CLUSTER: AR.6.135