ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 6.12.1

Subclass Accession number: 423
Subclass: 6.12.1

Type: HE alpha-beta
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 2 (>75 %)  2.3 (>75 %)  2.3.1 (>75 %)
GO : GO:0008415 (>75 %)  GO:0016746 (>75 %)  GO:0016747 (>75 %)
SCOP : 53900 (>75 %)  53901 (>75 %)  53902 (>75 %)

Number of loops: 4

Average sequence ID (%) : 21.6 +/- 20.6
Average RMSD (Å) : 0.675 +/- 0.096

Consensus geometry

d (Å): 11

delta (°): 45-90

theta (°): 135-180

rho (°): 45-90

Consensus Sequence:	ppXPhXpXhX
(φψ)-conformation:	aapppgppbb

Pattern:	[EKQT]	x	[ALV]	[ILVW]	[ADQT]	x	[IL]	[AERT]	[AENT]	[HIL]	[P]	[ACP]	[EG]	[EK]	[KPT]	[LV]	x
Conservation:	-0.216	-0.769	-0.195	-0.327	-0.659	-0.991	0.841	-0.622	-0.585	-0.432	3.103	-0.125	0.493	0.939	-0.022	0.595	-1.028

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1fsu_*_211	1fsu	-	217	233	KRAIALITNHPPEKPLF	HHHHHHHHT--TTS-EE	aaaaaaaaaxxpvbwbb
1odo_A_108	1odo	A	123	139	TGLVDRLAELPAGEPVD	HHHHHHHHHS-TTS-EE	aaaaaaaaaxpxvxxbx
1qj4_A_59	1qj4	A	59	75	EPLLTFLEALPPGEKVI	HHHHHHHHTS-TT--EE	aaaaaaaaaxxpvxbbb
1sfe_*_95	1sfe	-	98	114	QQVWQALRTIPCGETVS	HHHHHHHTTS-TT--EE	aaaaaaaaaxxxgbbbx

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1fsu_*_211	1fsu	*	NAGN-ACETYL-D-GLUCOSAMINE	T - 212
1fsu_*_211	1fsu	*	NAGN-ACETYL-D-GLUCOSAMINE	N - 213
1fsu_*_211	1fsu	*	NAGN-ACETYL-D-GLUCOSAMINE	I - 214
1fsu_*_211	1fsu	*	NAGN-ACETYL-D-GLUCOSAMINE	T - 216
1fsu_*_211	1fsu	*	NAGN-ACETYL-D-GLUCOSAMINE	K - 217
1fsu_*_211	1fsu	*	NAGN-ACETYL-D-GLUCOSAMINE	I - 220
1qj4_A_59	1qj4	A	GOLGLYCEROL	E - 79

Clusters included in this Subclass

CLUSTER: HE.7.16