ArchDB - Biological DataBase of Protein Loops

Grup de Recerca en Informàtica Biomèdica

Information on SUBCLASS 12.2.1

Subclass Accession number: 4283
Subclass: 12.2.1

PSSM

Type: AR beta-beta link
DB: ArchDB95

Image coordinates:

Rasmol PDB

Jmol PDB

Consensus coordinates:

Rasmol PDB

Jmol PDB

Number of loops: 9

Average sequence ID (%) : 44.6 +/- 28.6
Average RMSD (Å) : 0.389 +/- 0.136

Consensus geometry

d (Å): 19

delta (°): 90-135

theta (°): 45-90

rho (°): 135-180

Consensus Sequence:	XhGhhcppXhpGphpp
(φψ)-conformation:	bblbbpaaabbebpbb

Pattern:	x	[lvy]	x	[fil]	[g]	[fgy]	[ivy]	[den]	[denst]	[rst]	x	[fly]	[egkt]	[g]	[dps]	[il]	[ant]	[twy]	[tv]	[adgp]
Conservation:	-1.103	-0.248	-1.198	0.292	2.333	-0.431	0.110	0.609	-0.421	-0.202	-1.141	0.722	-0.857	2.333	-0.315	0.576	-0.100	0.525	-0.469	-1.015

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1bxo_A_163	1bxo	A	164	183	VYDFGFIDSSKYTGSLTYTG	EEEESS--GGGBSS--EEEE	bbxbvbbxaaabxebxbxbx
1ibq_A_160	1ibq	A	163	182	VYDFGYIDDSKYTGSITYTD	EEEESS--GGGBSS--EEEE	bbbbvbbxaaabbexxbbbx
1oew_A_166	1oew	A	167	186	TYNFGFIDTTAYTGSITYTA	EEEES---TTSSSS--EEEE	bbbbvbbxaaabbebxbxbx
1pfz_A_165	1pfz	A	167	186	FLTIGGIEERFYEGPLTYEK	EEEESS--GGGBSS--EEEE	bbbbvbbxaaabbexxbxbx
1pso_E_164	1pso	E	164	183	VVIFGGIDSSYYTGSLNWVP	EEEET---GGGBSS--EEEE	bbbxvbbbaaabbebxxbbx
2apr_*_167	2apr	-	168	187	EYIFGGYDSTKFKGSLTTVP	EEEET---GGGB-S--EEEE	bbbxvbbbaaabbexxbxbx
2asi_*_179	2asi	-	181	200	EVVFGGVNNTLLGGDIAYTD	EEEES---GGGBSS--EEEE	bbbxvbbxaaaxaebxbbbx
3psg_*_163	3psg	-	164	183	VVLLGGIDSSYYTGSLNWVP	EEEET---GGGBSS--EEEE	bbxxvbbbaaabbebxbxbx
4pep_*_163	4pep	-	164	183	VVLLGGIDSSYYTGSLNWVP	EEEET---TTSB-S--EEEE	bbbxvbbbaaabbebxbbbx

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1bxo_A_163	1bxo	A	MANALPHA-D-MANNOSE	G - 163
1bxo_A_163	1bxo	A	MANALPHA-D-MANNOSE	V - 164
1bxo_A_163	1bxo	A	MANALPHA-D-MANNOSE	F - 167
1bxo_A_163	1bxo	A	MANALPHA-D-MANNOSE	G - 168
1bxo_A_163	1bxo	A	MANALPHA-D-MANNOSE	F - 169
1bxo_A_163	1bxo	A	GOLGLYCEROL	S - 172
1bxo_A_163	1bxo	A	GOLGLYCEROL	Y - 175
1bxo_A_163	1bxo	A	GOLGLYCEROL	G - 177
1bxo_A_163	1bxo	A	GOLGLYCEROL	S - 178
2asi_*_179	2asi	*	NAGN-ACETYL-D-GLUCOSAMINE	E - 181
2asi_*_179	2asi	*	NAGN-ACETYL-D-GLUCOSAMINE	V - 183
2asi_*_179	2asi	*	NAGN-ACETYL-D-GLUCOSAMINE	N - 188
2asi_*_179	2asi	*	NAGN-ACETYL-D-GLUCOSAMINE	N - 189
2asi_*_179	2asi	*	NAGN-ACETYL-D-GLUCOSAMINE	T - 190
2asi_*_179	2asi	*	NAGN-ACETYL-D-GLUCOSAMINE	L - 191

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1oew_A_166	1oew	A	AC4SO4 BINDING SITE FOR CHAIN A	Y - 178
1oew_A_166	1oew	A	AC4SO4 BINDING SITE FOR CHAIN A	S - 181
1oew_A_166	1oew	A	AC4SO4 BINDING SITE FOR CHAIN A	I - 182

Clusters included in this Subclass

CLUSTER: AR.11.2