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Information on SUBCLASS 12.12.1
Subclass Accession number: 4293
Subclass: 12.12.1 PSSM
Type: AR beta-beta link
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 5.2 (>75 %)  5.2.1 (>75 %)  5.2.1.8
GO : GO:0003755 (>75 %)  GO:0016853 (>75 %)  GO:0016859 (>75 %)  
SCOP : 50890 (>75 %)  50891 (>75 %)  50892 (>75 %)  
 Number of loops: 3

Average sequence ID (%) : 71.0 +/- -26.2
Average RMSD (Å) : 0.167 +/- 0.058

Consensus geometry
d (Å): 9 delta (°): 90-135 theta (°): 45-90 rho (°): 180-225
Consensus Sequence: hXTVXXXXLDGKHVVF
(φψ)-conformation: bpabwaaaaplabppN
Pattern: [F][F][IL][CT][T][V][KP][CT][EP][HW][L][D][G][K][H][V][V][F][G][EQR][V][IV][DEK]
Conservation:1.0651.065-0.864-0.9740.420-0.225-1.105-1.007-1.105-0.186-0.2251.0651.0650.4202.354-0.225-0.2251.0651.065-1.300-0.225-0.542-1.372
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1dyw_A_1191dyw   A119141FFLCTVKTEWLDGKHVVFGRVVEEEEESS--GGGTTTS-EEEEEEEbbbxabxaaaapvabxxNebxab
1ihg_A_1321ihg   A132154FFITTVPTPHLDGKHVVFGQVIKEEEESS--GGGTTTS-EEEEEEEbbbxabwaaaapvabxxNbbxab
1ist_A_1101ist   A110132FFITTVPCPWLDGKHVVFGEVVDEEEESS--GGGTTTS-EEEEEEEbbbxabwaaaapvabxxabbxab
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1dyw_A_1191dyw   A CBSCYCLOSPORIN BINDING SITEF - 120
1dyw_A_1191dyw   A CBSCYCLOSPORIN BINDING SITEW - 128
1dyw_A_1191dyw   A CBSCYCLOSPORIN BINDING SITEH - 133

Clusters included in this Subclass
CLUSTER: AR.12.36