ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 1.1.69

Subclass Accession number: 4416
Subclass: 1.1.69

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 2.5 (>75 %)  2.5.1 (>75 %)  2.5.1.18
GO : GO:0004364 (>75 %)  GO:0016765 (>75 %)
SCOP : 47615 (>75 %)  47616 (>75 %)  47617 (>75 %)

Number of loops: 2

Average sequence ID (%) : 59.6 +/- 0.0
Average RMSD (Å) : 0.300 +/- 0.000

Consensus geometry

d (Å): 5

delta (°): 45-90

theta (°): 135-180

rho (°): 90-135

Consensus Sequence:	CYSPD
(φψ)-conformation:	aapaa

Pattern:	[E]	x	[E]	[KR]	x	[R]	[V]	[D]	[V]	[L]	[E]	[N]	[HQ]	[AL]	[M]	[D]	[LT]	[R]	[LM]	[AQ]	[FL]	[A]	[MR]	[LV]	[C]	[Y]	[S]	[P]	[D]	[F]	[E]	[KR]	[KL]	[K]	[P]	[AE]	[Y]	[L]	[E]	[GQ]	[L]	[P]	[EG]	[K]	[LM]	[KR]	x	[LY]	[S]	[ER]	[F]	[L]
Conservation:	0.478	-1.493	0.478	-0.311	-1.756	0.478	-0.048	1.003	-0.048	-0.048	0.478	1.003	-0.442	-1.362	0.478	1.003	-1.231	0.478	-0.442	-1.231	-0.836	-0.048	-1.099	-0.836	2.580	1.529	-0.048	1.529	1.003	1.003	0.478	-0.311	-1.493	0.478	1.529	-1.231	1.529	-0.048	0.478	-1.231	-0.048	1.529	-1.231	0.478	-0.442	-0.311	-1.493	-0.968	-0.048	-0.836	1.003	-0.048

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1b4p_A_90	1b4p	A	90	141	EEERIRVDVLENQAMDTRLQLAMVCYSPDFERKKPEYLEGLPEKMKLYSEFL	HHHHHHHHHHHHHHHHHHHHHHHHHH-TTHHHHHHHHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaaaaaaaaaaaxaaaaaaaaaaaaaaaaaaaaaaaaa
1gsu_A_90	1gsu	A	90	141	EVEKQRVDVLENHLMDLRMAFARLCYSPDFEKLKPAYLEQLPGKLRQLSRFL	HHHHHHHHHHHHHHHHHHHHHHHHHHSTTHHHHHHHHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaaaaaaaaaaaxaaaaaaaaaaaaaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1b4p_A_90	1b4p	A	GPS(9S,10S)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE	M - 104
1b4p_A_90	1b4p	A	GPS(9S,10S)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE	R - 107
1b4p_A_90	1b4p	A	GPS(9S,10S)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE	L - 108
1b4p_A_90	1b4p	A	GPS(9S,10S)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE	A - 111
1b4p_A_90	1b4p	A	GPS(9S,10S)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE	Y - 115
1gsu_A_90	1gsu	A	GTXS-HEXYLGLUTATHIONE	N - 101
1gsu_A_90	1gsu	A	GTXS-HEXYLGLUTATHIONE	M - 104
1gsu_A_90	1gsu	A	GTXS-HEXYLGLUTATHIONE	D - 105
1gsu_A_90	1gsu	A	GTXS-HEXYLGLUTATHIONE	M - 108
1gsu_A_90	1gsu	A	GTXS-HEXYLGLUTATHIONE	A - 111
1gsu_A_90	1gsu	A	GTXS-HEXYLGLUTATHIONE	Y - 115

Clusters included in this Subclass

CLUSTER: HH.3.216