ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 2.1.50

Subclass Accession number: 4550
Subclass: 2.1.50

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 3.1 (>50 %)  3.1.1 (>50 %)  3.1.1.3
GO : GO:0016298 (>50 %)  GO:0016788 (>50 %)  GO:0016789 (>50 %)
SCOP : 53473 (>50 %)  53474 (>50 %)  53577 (>50 %)

Number of loops: 3

Average sequence ID (%) : 32.1 +/- 30.4
Average RMSD (Å) : 0.700 +/- 0.265

Consensus geometry

d (Å): 7

delta (°): 0-45

theta (°): 90-135

rho (°): 225-270

Consensus Sequence:	XpXXpp
(φψ)-conformation:	aappaa

Pattern:	[KT]	[G]	[FG]	x	[EKR]	[ALT]	x	[QY]	[NST]	[DQ]	[AQ]	x	x	x	[IL]	[KR]	x	[GV]	[CG]	[AL]	[E]	[V]	[AV]	[LY]	[FLV]	x	[EMQ]
Conservation:	-0.073	3.006	-0.445	-0.316	0.154	-0.883	-1.315	0.414	-0.019	0.462	-0.316	-0.850	-0.607	-0.748	0.683	1.078	-0.796	-0.931	0.008	-0.467	2.228	1.450	-0.083	0.262	-0.451	-1.082	-0.364

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1gpl_*_107	1gpl	-	107	133	KGGSKAQYSQASQNIRVVGAEVAYLVQ	HHHHTS-HHHHHHHHHHHHHHHHHHHH	aaaaaxxaaaaaaaaaaaaaaaaaaaa
1lpb_B_107	1lpb	B	107	133	KGGSRTGYTQASQNIRIVGAEVAYFVE	HHHHSS-HHHHHHHHHHHHHHHHHHHH	aaaaabxaaaaaaaaaaaaaaaaaaaa
1nq7_A_281	1nq7	A	281	307	TGFMELCQNDQILLLKSGCLEVVLVRM	HHHHTS-HHHHHHHHHHHHHHHHHHHH	aaaaaxxaaaaaaaaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1lpb_B_107	1lpb	B	BOGB-OCTYLGLUCOSIDE	R - 111
1lpb_B_107	1lpb	B	MUPMETHOXYUNDECYLPHOSPHINIC ACID	Y - 114
1nq7_A_281	1nq7	A	ARL7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC ACID	L - 300
1nq7_A_281	1nq7	A	ARL7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC ACID	E - 301
1nq7_A_281	1nq7	A	ARL7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC ACID	V - 303
1nq7_A_281	1nq7	A	ARL7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC ACID	L - 304
1nq7_A_281	1nq7	A	ARL7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC ACID	R - 306
1nq7_A_281	1nq7	A	ARL7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC ACID	M - 307

Clusters included in this Subclass