ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 6.53.1

Subclass Accession number: 4996
Subclass: 6.53.1

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 2.7 (>50 %)  2.7.1 (>50 %)
GO : GO:0016301 (>50 %)  GO:0016772 (>50 %)  GO:0016773 (>50 %)
SCOP : 53612 (>50 %)  53613 (>50 %)

Number of loops: 3

Average sequence ID (%) : 26.9 +/- 18.6
Average RMSD (Å) : 1.300 +/- 0.500

Consensus geometry

d (Å): 15

delta (°): 90-135

theta (°): 45-90

rho (°): 315-360

Consensus Sequence:	XXXXXVppXE
(φψ)-conformation:	aalbpbabaa

Pattern:	x	[TV]	x	[ALW]	[CE]	[IK]	[HL]	[ACT]	[EG]	x	[AKR]	[V]	[EKN]	[HN]	[DTV]	[E]	[DE]	[A]	[AKV]	x	[AI]	[AV]	[QR]	x	[HL]	[HIL]
Conservation:	-1.245	0.322	-0.583	-0.823	-0.396	-0.731	-0.441	-0.063	0.029	-0.992	-0.232	1.626	0.106	1.576	-0.823	2.386	1.432	1.626	-0.823	-0.738	-0.162	0.196	1.010	-1.076	-0.441	-0.738

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1ed1_A_73	1ed1	A	83	108	CVIWCIHAEEKVKHTEEAKQIVQRHL	HHHHHHHTT---SBHHHHHHHHHHHH	aaaaaaaavxxbabaaaaaaaaaaaa
1rkd_*_188	1rkd	-	188	213	ETEAEKLTGIRVENDEDAAKAAQVLH	HHHHHHHHS---SSHHHHHHHHHHHH	aaaaaaaavbxbabaaaaaaaaaaaa
1vi9_A_147	1vi9	A	147	172	LVELEILCEHAVNNVEEAVLAARELI	HHHHHHHHTS---SHHHHHHHHHHHH	aaaaaaaavbxbabaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1ed1_A_73	1ed1	A	IPAISOPROPYL ALCOHOL	L - 75
1ed1_A_73	1ed1	A	IPAISOPROPYL ALCOHOL	H - 96
1ed1_A_73	1ed1	A	IPAISOPROPYL ALCOHOL	E - 98
1ed1_A_73	1ed1	A	IPAISOPROPYL ALCOHOL	E - 99
1ed1_A_73	1ed1	A	IPAISOPROPYL ALCOHOL	Q - 102
1rkd_*_188	1rkd	*	ADPADENOSINE-5'-DIPHOSPHATE	E - 188
1rkd_*_188	1rkd	*	PO4PHOSPHATE ION	T - 189
1rkd_*_188	1rkd	*	ADPADENOSINE-5'-DIPHOSPHATE	E - 190
1rkd_*_188	1rkd	*	PO4PHOSPHATE ION	E - 190
1vi9_A_147	1vi9	A	MSESELENOMETHIONINE	V - 148
1vi9_A_147	1vi9	A	MSESELENOMETHIONINE	E - 149
1vi9_A_147	1vi9	A	MSESELENOMETHIONINE	I - 152
1vi9_A_147	1vi9	A	MSESELENOMETHIONINE	L - 153

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1rkd_*_188	1rkd	*	AB2RESIDUES MAKING WATER-MEDIATED HYDROGEN BONDS WITH ADP.	E - 190

Clusters included in this Subclass

CLUSTER: HH.6.155