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Information on SUBCLASS 7.10.1
Subclass Accession number: 5013
Subclass: 7.10.1 PSSM
Type: HH alpha-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 4.1 (>75 %)  4.1.1 (>75 %)  4.1.1.39
GO : GO:0000287 (>50 %)  GO:0004497 (>75 %)  GO:0016829 (>75 %)  GO:0016830 (>75 %)  GO:0016831 (>75 %)  GO:0016984 (>75 %)  
SCOP : 51649 (>75 %)  51650 (>75 %)  
 Number of loops: 5

Average sequence ID (%) : 15.0 +/- 24.3
Average RMSD (Å) : 1.260 +/- 0.477

Consensus geometry
d (Å): 15 delta (°): 90-135 theta (°): 90-135 rho (°): 180-225
Consensus Sequence: pppppXpLpXX
(φψ)-conformation: aabaappbpaa
Pattern: xxxxx[ST][de][DGKST][DES][aefl][AEQRS][FL][HST][dpq]xxxx[GIL][FLY]
Conservation:-0.741-0.807-0.649-1.068-0.4142.2100.331-0.5251.268-1.279-0.0062.0270.710-0.699-0.195-0.750-0.3490.040-0.3651.263
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1i7g_A_4221i7g   A445464QIIKKTESDAALHPLLQEIYHHHHHH-TT----HHHHHHHaaaaaaxaaxbbpaaaaaaa
1jms_A_2741jms   A274293LSKIQSDKSLRFTQMQKAGFHHHHHH-SS----HHHHHHHaaaaaapaaxbbxaaaaaaa
1o9d_A_241o9d   A3251EKVSNSLGSEELTVEERNLLHHHHHT-SSS---HHHHHHHaaaaaabFaxxxxaaaaaaa
1tmk_A_441tmk   A4968INEYLTDDSFQLSDQAIHLLHHHHHH-TT----HHHHHHHaaaaaabaaxxbpaaaaaaa
2gwx_A_4312gwx   A454473QRIKKTETETSLHPLLQEIYHHHHHH-TTS---HHHHHHHaaaaaabaaxxbpaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1i7g_A_4221i7g   A     AZ2(2S)-2-ETHOXY-3-[4-(2-{4-[(METHYLSULFONYL)OXY]PHENYL} ETHOXY)PHENYL]PROPANOIC ACID H - 440
1i7g_A_4221i7g   A     AZ2(2S)-2-ETHOXY-3-[4-(2-{4-[(METHYLSULFONYL)OXY]PHENYL} ETHOXY)PHENYL]PROPANOIC ACID V - 444
1i7g_A_4221i7g   A     AZ2(2S)-2-ETHOXY-3-[4-(2-{4-[(METHYLSULFONYL)OXY]PHENYL} ETHOXY)PHENYL]PROPANOIC ACID I - 447
1i7g_A_4221i7g   A     AZ2(2S)-2-ETHOXY-3-[4-(2-{4-[(METHYLSULFONYL)OXY]PHENYL} ETHOXY)PHENYL]PROPANOIC ACID L - 456
1i7g_A_4221i7g   A     AZ2(2S)-2-ETHOXY-3-[4-(2-{4-[(METHYLSULFONYL)OXY]PHENYL} ETHOXY)PHENYL]PROPANOIC ACID L - 460
1i7g_A_4221i7g   A     AZ2(2S)-2-ETHOXY-3-[4-(2-{4-[(METHYLSULFONYL)OXY]PHENYL} ETHOXY)PHENYL]PROPANOIC ACID Y - 464
1o9d_A_241o9d   A     TPOPHOSPHOTHREONINE K - 56
1o9d_A_241o9d   A     TPOPHOSPHOTHREONINE R - 63
1o9d_A_241o9d   A     TPOPHOSPHOTHREONINE R - 67
1tmk_A_441tmk   A     TMPTHYMIDINE-5'-PHOSPHATE I - 49
1tmk_A_441tmk   A     TMPTHYMIDINE-5'-PHOSPHATE L - 53
1tmk_A_441tmk   A     TMPTHYMIDINE-5'-PHOSPHATE H - 66
1tmk_A_441tmk   A     TMPTHYMIDINE-5'-PHOSPHATE F - 69
1tmk_A_441tmk   A     TMPTHYMIDINE-5'-PHOSPHATE S - 70
1tmk_A_441tmk   A     TMPTHYMIDINE-5'-PHOSPHATE R - 73

Clusters included in this Subclass
CLUSTER: HH.7.43