ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 7.15.1

Subclass Accession number: 5018
Subclass: 7.15.1

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 1.14 (>50 %)  1.14.99 (>50 %)  1.14.99.1 2.8 (>75 %)  2.8.2 (>75 %)  2.8.2.4
GO : GO:0004304 (>75 %)  GO:0005496 (>75 %)  GO:0008146 (>75 %)  GO:0016782 (>75 %)
SCOP : 48112 (>75 %)  48113 (>75 %)  48132 (>75 %)  52539 (>75 %)  52540 (>75 %)  52575 (>75 %)

Number of loops: 4

Average sequence ID (%) : 56.7 +/- 18.2
Average RMSD (Å) : 0.200 +/- 0.000

Consensus geometry

d (Å): 7

delta (°): 0-45

theta (°): 0-45

rho (°): 45-90

Consensus Sequence:	hXGpVXhGSWh
(φψ)-conformation:	aalabplepaa

Pattern:	[FPW]	[DPS]	[EQS]	[F]	[LV]	[ER]	[DK]	[F]	[LM]	[AKQ]	[G]	[EQ]	[V]	[PQS]	[FY]	[G]	[S]	[W]	[FY]	[DKQ]	[H]	[IV]	[KQ]	[AEGS]	[W]
Conservation:	-1.085	-0.906	-0.754	0.673	-0.572	-0.545	-0.661	0.673	-0.257	-0.994	0.673	-0.213	-0.046	-0.993	0.290	0.673	-0.046	2.471	0.290	-0.816	1.392	-0.218	-0.356	-1.147	2.471

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1aqu_A_155	1aqu	A	155	179	FSEFVEKFMQGQVPYGSWYDHVKAW	HHHHHHHHHHT-STT--HHHHHHHH	aaaaaaaaaavabpvexaaaaaaaa
1cjm_A_155	1cjm	A	155	179	WDSFLEKFMAGEVSYGSWYQHVQEW	HHHHHHHHHTT-STT--HHHHHHHH	aaaaaaaaaavabpvepaaaaaaaa
1g3m_A_154	1g3m	A	154	178	FPEFVEKFMQGQVPYGSWYKHVKSW	HHHHHHHHHTT-STTS-HHHHHHHH	aaaaaaaaaavabpvexaaaaaaaa
1q20_A_172	1q20	A	172	196	PDQFLRDFLKGEVQFGSWFDHIKGW	HHHHHHHHHTT-STTS-HHHHHHHH	aaaaaaaaaavabpvexaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1aqu_A_155	1aqu	A	ESTESTRADIOL	Y - 169
1g3m_A_154	1g3m	A	PCQ3,5,3',5'-TETRACHLORO-BIPHENYL-4,4'-DIOL	Y - 168
1g3m_A_154	1g3m	A	EDO1,2-ETHANEDIOL	K - 173
1g3m_A_154	1g3m	A	EDO1,2-ETHANEDIOL	K - 176
1g3m_A_154	1g3m	A	EDO1,2-ETHANEDIOL	S - 177
1g3m_A_154	1g3m	A	EDO1,2-ETHANEDIOL	W - 178
1g3m_A_154	1g3m	A	EDO1,2-ETHANEDIOL	E - 180
1q20_A_172	1q20	A	PLO(3BETA)-3-HYDROXYPREGN-5-EN-20-ONE	Q - 185
1q20_A_172	1q20	A	PLO(3BETA)-3-HYDROXYPREGN-5-EN-20-ONE	F - 186

Clusters included in this Subclass