ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 8.22.1

Subclass Accession number: 5051
Subclass: 8.22.1

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
GO : GO:0005083 (>50 %) GO:0005085 (>50 %) GO:0005515 (>50 %) GO:0008603 (>50 %) GO:0016208 (>50 %) GO:0019207 (>50 %) GO:0019887 (>50 %) GO:0030551 (>50 %) GO:0030552 (>50 %) GO:0030554 (>50 %) GO:0030695 (>50 %)
SCOP : 51181 (>50 %) 51206 (>50 %) 51210 (>50 %)

Number of loops: 3

Average sequence ID (%) : 16.1 +/- 15.1
Average RMSD (Å) : 0.667 +/- 0.058

Consensus geometry

d (Å): 13

delta (°): 90-135

theta (°): 90-135

rho (°): 270-315

Consensus Sequence:	XXhpXXpphXXX
(φψ)-conformation:	aapaaaaabpaa

Pattern:	[AD]	[ALV]	[DEH]	[AI]	[I]	[FHY]	[DNT]	[EGR]	[L]	[KLT]	x	[ILV]	[EK]	[AN]	[FLT]	[EHS]	[HK]	[FLY]	x	[HPT]	[GNT]	x	[KL]	x	[AEQ]	[IL]	[ACG]	[GLV]	[CLV]
Conservation:	0.272	-0.437	0.529	-0.081	2.140	1.389	0.100	-0.866	2.140	-1.081	-1.511	0.852	1.330	-0.277	-0.759	-0.115	0.832	0.529	-1.296	-0.652	-0.330	-1.189	-0.041	-0.570	-0.222	1.268	-0.330	-1.511	-0.115

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1kq3_A_250	1kq3	A	250	278	AAHAIHNGLTVLENTHKYLHGEKVAIGVL	HHHHHHHHHTTSGGGTTS-HHHHHHHHHH	aaaaaaaaaaabaaaaaxxaaaaaaaaaa
1o7f_A_28	1o7f	A	30	58	DVDIIFTRLKGVKAFEKFHPNLLRQICLC	HHHHHHHHHTT-TTTTT--HHHHHHHHHH	aaaaaaaaaaaxaaaaabxaaaaaaaaaa
1o7f_A_323	1o7f	A	325	353	DLEIIYDELLHIKALSHLSTTVKRELAGV	HHHHHHHHHTT-GGGTTS-HHHHHHHHHH	aaaaaaaaaaaxaaaaabpaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1kq3_A_250	1kq3	A	ZNZINC ION	H - 252
1kq3_A_250	1kq3	A	TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	H - 252
1kq3_A_250	1kq3	A	ZNZINC ION	H - 269
1kq3_A_250	1kq3	A	TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	H - 269
1kq3_A_250	1kq3	A	ZNZINC ION	V - 273
1kq3_A_250	1kq3	A	TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	V - 273

Clusters included in this Subclass