ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 9.15.1

Subclass Accession number: 5083
Subclass: 9.15.1

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 1.7 (>50 %)  1.7.2 (>50 %)  1.7.2.3 3.4 (>75 %)  3.4.22 (>75 %)
GO : GO:0030151 (>50 %)
SCOP : 53705 (>75 %)  53706 (>75 %)  53707 (>75 %)  54000 (>75 %)  54001 (>75 %)  54002 (>75 %)

Number of loops: 3

Average sequence ID (%) : 59.1 +/- -4.5
Average RMSD (Å) : 0.200 +/- 0.100

Consensus geometry

d (Å): 13

delta (°): 90-135

theta (°): 45-90

rho (°): 315-360

Consensus Sequence:	XXcNpGCpGGhhX
(φψ)-conformation:	aagpaeaaeebaa

Pattern:	[E]	[Q]	[NQ]	[L]	[V]	[D]	[C]	[AS]	[GQR]	[NP]	[FQ]	[GN]	[N]	[EHQ]	[G]	[C]	[NQ]	[G]	[G]	[FL]	[MP]	[ADS]	[QRY]	[A]	[F]	[EQ]	[Y]	[IV]	[KQR]	[DEY]	[N]
Conservation:	0.433	0.433	-0.550	-0.020	-0.020	0.886	2.246	-0.693	-1.330	-0.769	-1.269	-0.459	0.886	-0.725	0.886	2.246	-0.550	0.886	0.886	-0.746	-0.954	-1.229	-1.179	-0.020	0.886	-0.240	1.340	-0.244	-0.675	-1.229	0.886

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1fh0_A_50	1fh0	A	50	80	EQNLVDCSRPQGNQGCNGGFMARAFQYVKEN	HHHHHHH-GGGT--GGG---HHHHHHHHHHH	aaaaaaaaaaagxaeaaebbaaaaaaaaaaa
1mhw_A_50	1mhw	A	50	80	EQNLVDCSGPQGNEGCNGGLMDYAFQYVQDN	HHHHHHH-TTTT--GGG---HHHHHHHHHHH	aaaaaaaaaaagxaeaaeebaaaaaaaaaaa
8pch_A_50	8pch	A	50	80	EQQLVDCAQNFNNHGCQGGLPSQAFEYIRYN	HHHHHHHGGGGT--GGG---HHHHHHHHHHH	aaaaaaaaaaavbaeaaeebaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1fh0_A_50	1fh0	A	ODS4-METHYLPIPERAZIN-1-YL CARBONYL GROUP	G - 61
1fh0_A_50	1fh0	A	ODS4-METHYLPIPERAZIN-1-YL CARBONYL GROUP	N - 62
1fh0_A_50	1fh0	A	ODS4-METHYLPIPERAZIN-1-YL CARBONYL GROUP	Q - 63
1fh0_A_50	1fh0	A	NFP3-AMINO-5-PHENYLPENTANE	C - 65
1fh0_A_50	1fh0	A	ODS4-METHYLPIPERAZIN-1-YL CARBONYL GROUP	N - 66
1fh0_A_50	1fh0	A	NFP3-AMINO-5-PHENYLPENTANE	N - 66
1fh0_A_50	1fh0	A	ODS4-METHYLPIPERAZIN-1-YL CARBONYL GROUP	G - 67
1fh0_A_50	1fh0	A	NFP3-AMINO-5-PHENYLPENTANE	G - 67
1fh0_A_50	1fh0	A	ODS4-METHYLPIPERAZIN-1-YL CARBONYL GROUP	G - 68
1fh0_A_50	1fh0	A	NFP3-AMINO-5-PHENYLPENTANE	G - 68
1fh0_A_50	1fh0	A	ODS4-METHYLPIPERAZIN-1-YL CARBONYL GROUP	F - 69
1mhw_A_50	1mhw	A	PEA2-PHENYLETHYLAMINE	G - 61
1mhw_A_50	1mhw	A	PEA2-PHENYLETHYLAMINE	N - 62
1mhw_A_50	1mhw	A	PEA2-PHENYLETHYLAMINE	E - 63
1mhw_A_50	1mhw	A	DARD-ARGININE	C - 65
1mhw_A_50	1mhw	A	DARD-ARGININE	N - 66
1mhw_A_50	1mhw	A	PEA2-PHENYLETHYLAMINE	N - 66
1mhw_A_50	1mhw	A	CSWCYSTEINE-S-DIOXIDE	G - 67
1mhw_A_50	1mhw	A	DARD-ARGININE	G - 67
1mhw_A_50	1mhw	A	PEA2-PHENYLETHYLAMINE	G - 67
1mhw_A_50	1mhw	A	DARD-ARGININE	G - 68
1mhw_A_50	1mhw	A	PEA2-PHENYLETHYLAMINE	G - 68
1mhw_A_50	1mhw	A	DARD-ARGININE	L - 69
1mhw_A_50	1mhw	A	PEA2-PHENYLETHYLAMINE	L - 69
1mhw_A_50	1mhw	A	CSWCYSTEINE-S-DIOXIDE	M - 70
1mhw_A_50	1mhw	A	PEA2-PHENYLETHYLAMINE	Y - 72
8pch_A_50	8pch	A	NAGN-ACETYL-D-GLUCOSAMINE	N - 59

Clusters included in this Subclass

CLUSTER: HH.12.17