ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 10.6.1

Subclass Accession number: 5103
Subclass: 10.6.1

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 2.7 (>75 %)  2.7.1 (>75 %)  2.7.1.37 2.7.2 (>75 %)  2.7.2.3 (>75 %)
GO : GO:0004618 (>75 %)  GO:0004672 (>75 %)  GO:0016301 (>75 %)  GO:0016301 (>75 %)  GO:0016772 (>75 %)  GO:0016773 (>75 %)  GO:0016774 (>75 %)
SCOP : 53747 (>75 %)  53748 (>75 %)  53749 (>75 %)  56111 (>75 %)  56112 (>75 %)  88854 (>75 %)

Number of loops: 4

Average sequence ID (%) : 54.9 +/- 17.3
Average RMSD (Å) : 0.375 +/- 0.150

Consensus geometry

d (Å): 9

delta (°): 90-135

theta (°): 45-90

rho (°): 180-225

Consensus Sequence:	AXGpphGpSXhEEp
(φψ)-conformation:	aagppaeappbpaa

Pattern:	[AM]	[FY]	[T]	[F]	[LV]	[K]	[A]	x	[G]	x	[DES]	[IV]	[G]	[KRS]	[S]	x	[CLV]	[E]	[E]	[DS]	[KR]	[IL]	[DE]	[FL]	[A]	[KR]	[DES]	[FL]	[LMV]	[EGK]	[KR]	[A]	[EK]	[ADE]
Conservation:	-0.942	1.004	1.153	1.816	-0.419	1.153	0.490	-1.280	1.816	-1.748	-0.711	0.180	1.816	-0.853	0.490	-1.565	-1.082	1.153	1.153	-0.231	0.240	-0.171	0.312	-0.566	0.490	0.222	-0.862	-0.556	-0.591	-1.366	0.240	0.490	-0.169	-1.105

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
16pk_*_243	16pk	-	244	277	AYTFLKAQGYSIGKSKCEESKLEFARSLLKKAED	HHHHHHHHT---TT----GGGHHHHHHHHHHHHH	aaaaaaaagxxaeaxxbbaaaaaaaaaaaaaaaa
1php_*_221	1php	-	222	255	AYTFVKALGHDVGKSLLEEDKIELAKSFMEKAKE	HHHHHHHTT---TTS---GGGHHHHHHHHHHHHH	aaaaaaaavbxaeaxpbbaaaaaaaaaaaaaaaa
1v6s_A_219	1v6s	A	219	252	AFTFLKALGGEVGRSLVEEDRLDLAKDLLGRAEA	HHHHHHHTT-B-TT----GGGHHHHHHHHHHHHH	aaaaaaaagxbaeaxxbxaaaaaaaaaaaaaaaa
1vpe_*_222	1vpe	-	222	255	MFTFLKALGKEVGSSRVEEDKIDLAKELVEKAKE	HHHHHHHTS---TTS---GGGHHHHHHHHHHHHH	aaaaaaaaGOxaeapxbxaaaaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
16pk_*_243	16pk	*	BIS1,1,5,5-TETRAFLUOROPHOSPHOPENTYLPHOSPHONIC ACID ADENYLATE ESTER	Y - 245
16pk_*_243	16pk	*	BIS1,1,5,5-TETRAFLUOROPHOSPHOPENTYLPHOSPHONIC ACID ADENYLATE ESTER	K - 259
1php_*_221	1php	*	ADPADENOSINE-5'-DIPHOSPHATE	L - 221
1php_*_221	1php	*	ADPADENOSINE-5'-DIPHOSPHATE	Y - 223
1php_*_221	1php	*	ADPADENOSINE-5'-DIPHOSPHATE	L - 237
1vpe_*_222	1vpe	*	ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	M - 222
1vpe_*_222	1vpe	*	ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	F - 223
1vpe_*_222	1vpe	*	ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	R - 237

Clusters included in this Subclass