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Information on SUBCLASS 11.2.1
Subclass Accession number: 5122
Subclass: 11.2.1 PSSM
Type: HH alpha-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 3.1 (>75 %)  3.1 (>75 %)  3.1.1 (>75 %)  3.1.1 (>75 %)  3.1.1.43.1.1.4
GO : GO:0005509 (>75 %)  GO:0005509 (>75 %)  GO:0016298 (>75 %)  GO:0016298 (>75 %)  GO:0016788 (>75 %)  GO:0016788 (>75 %)  GO:0016789 (>75 %)  GO:0016789 (>75 %)  
SCOP : 48618 (>75 %)  48618 (>75 %)  48619 (>75 %)  48619 (>75 %)  48623 (>75 %)  48623 (>75 %)  
 Number of loops: 11

Average sequence ID (%) : 67.1 +/- 23.2
Average RMSD (Å) : 0.382 +/- 0.117

Consensus geometry
d (Å): 25 delta (°): 90-135 theta (°): 45-90 rho (°): 315-360
Consensus Sequence: hcAPYNcXppNIDXp
(φψ)-conformation: aappbbaaaplppaa
Pattern: [c][ael][ar]x[stv][c][dn][c][d][r]x[a][a][fil][c][f][ags][gkn][as][ep][y][n][dekn][aegnt][dhn]x[n][il][dn][lt][akt][akrst][fry]
Conservation:2.038-0.930-0.566-1.079-0.7532.0380.2102.0380.964-0.625-1.1950.2480.248-0.4312.0380.964-0.524-0.694-0.2200.0011.322-0.513-0.570-1.044-0.228-1.0550.964-0.0540.227-0.464-0.716-0.876-0.759
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1ae7_*_901ae7   -91123CLRFVCDCDVEAAFCFAKAPYNNANWNIDTKKRHHHHHHHHHHHHHHHHHHS---GGGBS--HHHHaaaaaaaaaaaaaaaaaaxxxxaaaxlxxaaaa
1bun_A_861bun   A86118CARIVCDCDRTAALCFGNSEYIEGHKNIDTARFHHHHHHHHHHHHHHHHHHS---GGGBT--HHHHaaaaaaaaaaaaaaaaaabxxxaaaxvpxaaaa
1hn4_A_901hn4   A91123CEAFICNCDRNAAICFSKAPYNKEHKNLDTKKYHHHHHHHHHHHHHHHHHHS---GGGBT--HHHHaaaaaaaaaaaaaaaaaaxxbbaaaxlxxaaNa
1m8t_A_901m8t   A91123CAAFVCDCDRVAAICFAGAPYNKENINIDTTTRHHHHHHHHHHHHHHHHHHS---GGGBS--HHHHaaaaaaaaaaaaaaaaaabxbbaaaxlxxaaaa
1mh8_A_851mh8   A86118CAATTCDCDRLAAICFAGAPYNDTNYNIDLKARHHHHHHHHHHHHHHHHHHS---GGGBT--HHHHaaaaaaaaaaaaaaaaaaxxbxaaaxlxxaaaa
1ows_A_851ows   A86118CAASSCDCDRLAAICFAGAPYNDNNYNIDLKARHHHHHHHHHHHHHHHHHHS---GGGBS--HHHHaaaaaaaaaaaaaaaaaabpbxaaaxlxxaaaa
1ows_B_851ows   B86118CAATTCDCDRLAAICFAGAPYNDTNYNIDLKSRHHHHHHHHHHHHHHHHHHS---GGGBS--HHHHaaaaaaaaaaaaaaaaaaxxbbaaabvxxaaaa
1poa_*_841poa   -85117CAAAVCDCDRLAAICFAGAPYNDNDYNINLKARHHHHHHHHHHHHHHHHTTS---GGGBS--HHHHaaaaaaaaaaaaaaaaaabxxbaaaxlxxaaaa
1s6b_A_851s6b   A86118CAATVCDCDRLAAICFAGAPYNDNNYNIDLKARHHHHHHHHHHHHHHHHHHS---GGGBT--HHHHaaaaaaaaaaaaaaaaaaxxxbaaaxlxxaaaa
1sz8_A_851sz8   A86118CAASVCDCDRLAAICFAGAPYNDANYNIDLKARHHHHHHHHHHHHHHHHHHS---GGGBT--HHHHaaaaaaaaaaaaaaaaaaxxbbaaaxlxxaaaa
5p2p_A_905p2p   A91123CEAFICNCDRNAAICFSKAPYNKEHKNLDTKKYHHHHHHHHHHHHHHHHHTS---GGGBT--HHHHaaaaaaaaaaaaaaaaaabxbxaaaxlpxaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1hn4_A_901hn4   A     MJI1-HEXADECYL-3-TRIFLUOROETHYL-SN-GLYCERO-2-PHOSPHATE METHANE D - 99
1hn4_A_901hn4   A     MJI1-HEXADECYL-3-TRIFLUOROETHYL-SN-GLYCERO-2-PHOSPHATE METHANE A - 102
1hn4_A_901hn4   A     MJI1-HEXADECYL-3-TRIFLUOROETHYL-SN-GLYCERO-2-PHOSPHATE METHANE F - 106
1ows_A_851ows   A     NAGN-ACETYL-D-GLUCOSAMINE A - 97
1ows_A_851ows   A     NAGN-ACETYL-D-GLUCOSAMINE F - 101
1ows_A_851ows   A     ZNZINC ION N - 112
1ows_A_851ows   A     ZNZINC ION I - 113
1ows_A_851ows   A     ZNZINC ION L - 115
1poa_*_841poa   *     CACALCIUM ION N - 111
1poa_*_841poa   *     CACALCIUM ION I - 112
1poa_*_841poa   *     CACALCIUM ION L - 114
1s6b_A_851s6b   A     CACALCIUM ION N - 112
1s6b_A_851s6b   A     CACALCIUM ION I - 113
1s6b_A_851s6b   A     CACALCIUM ION L - 115
5p2p_A_905p2p   A     CACALCIUM ION E - 92
5p2p_A_905p2p   A     DHGPHOSPHONIC ACID 2-DODECANOYLAMINO-HEXYL ESTER PROPYL ESTER A - 102
5p2p_A_905p2p   A     DHGPHOSPHONIC ACID 2-DODECANOYLAMINO-HEXYL ESTER PROPYL ESTER F - 106
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1ae7_*_901ae7   * CNRSITE *CNR* COMPRISES THOSE RESIDUES FORMING THE CATALYTIC NETWORK.D - 99

Clusters included in this Subclass
CLUSTER: HH.12.1