ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 11.12.1

Subclass Accession number: 5132
Subclass: 11.12.1

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 2.5 (>75 %)  2.5.1 (>75 %)  2.5.1.18
GO : GO:0004364 (>75 %)  GO:0016765 (>75 %)
SCOP : 47615 (>75 %)  47616 (>75 %)  47617 (>75 %)

Number of loops: 3

Average sequence ID (%) : 79.8 +/- -45.1
Average RMSD (Å) : 0.433 +/- 0.153

Consensus geometry

d (Å): 23

delta (°): 0-45

theta (°): 45-90

rho (°): 0-45

Consensus Sequence:	FLQPGSXRKPPhDXK
(φψ)-conformation:	aapplpapbwpppaa

Pattern:	[P]	[NT]	[V]	[K]	[K]	[F]	[L]	[Q]	[P]	[G]	[S]	[PQ]	[R]	[K]	[P]	[P]	[LM]	[D]	[AE]	[K]	[QS]	[IL]	[EQ]	[E]	[A]	[R]	[K]	[AIV]
Conservation:	1.549	-1.136	-0.361	0.276	0.276	0.913	-0.361	0.276	1.549	0.913	-0.361	-1.344	0.276	0.276	1.549	1.549	-0.792	0.913	-1.806	0.276	-1.455	-0.996	-0.667	0.276	-0.361	0.276	0.276	-1.776

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1f3b_A_191	1f3b	A	191	218	PNVKKFLQPGSQRKPPMDAKQIQEARKA	HHHHHHHSTTSS------HHHHHHHHHH	aaaaaaaxpvxaxbwxbxaaaaaaaaaa
1k3y_A_192	1k3y	A	192	219	PTVKKFLQPGSPRKPPMDEKSLEEARKI	HHHHHHHSTTSS------HHHHHHHHHH	aaaaaaaxpvxapbxpxxaaaaaaaaaa
1ml6_A_191	1ml6	A	191	218	PNVKKFLQPGSQRKPPLDAKQIEEARKV	HHHHHHHSTTSS------HHHHHHHHHH	aaaaaaaxpvxaxbwxxxaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1f3b_A_191	1f3b	A	GBX2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7, 8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID	M - 207
1f3b_A_191	1f3b	A	GBX2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7, 8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID	A - 215
1f3b_A_191	1f3b	A	GBX2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7, 8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID	R - 216
1f3b_A_191	1f3b	A	GBX2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7, 8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID	K - 217
1f3b_A_191	1f3b	A	GBX2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7, 8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID	F - 219
1k3y_A_192	1k3y	A	GTXS-HEXYLGLUTATHIONE	M - 208
1k3y_A_192	1k3y	A	GTXS-HEXYLGLUTATHIONE	L - 213
1k3y_A_192	1k3y	A	GTXS-HEXYLGLUTATHIONE	A - 216
1k3y_A_192	1k3y	A	GTXS-HEXYLGLUTATHIONE	F - 220
1ml6_A_191	1ml6	A	GBX2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7, 8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID	L - 207
1ml6_A_191	1ml6	A	GBX2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7, 8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID	Q - 211
1ml6_A_191	1ml6	A	GBX2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7, 8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID	I - 212
1ml6_A_191	1ml6	A	CSOS-HYDROXYCYSTEINE	R - 216

Clusters included in this Subclass

CLUSTER: HH.10.78