ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 11.14.1

Subclass Accession number: 5134
Subclass: 11.14.1

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 3.1 (>75 %)  3.1.26 (>75 %)  3.1.26.4
GO : GO:0003723 (>75 %)  GO:0004518 (>75 %)  GO:0004519 (>75 %)  GO:0004540 (>75 %)  GO:0016788 (>75 %)  GO:0030145 (>75 %)  GO:0046914 (>75 %)
SCOP : 53066 (>75 %)  53098 (>75 %)  53099 (>75 %)

Number of loops: 3

Average sequence ID (%) : 28.0 +/- 19.9
Average RMSD (Å) : 1.000 +/- 0.265

Consensus geometry

d (Å): 19

delta (°): 135-180

theta (°): 45-90

rho (°): 180-225

Consensus Sequence:	XpcphPXhhRXXWKT
(φψ)-conformation:	aalbppaappaapaa

Pattern:	[KPR]	[RT]	x	[AKR]	[EF]	[LV]	[EL]	[DKN]	[EY]	[FWY]	x	[AEK]	[HS]	[GK]	[EKR]	[FIL]	[P]	[DPS]	[CI]	[AV]	[R]	[KMT]	x	[W]	[K]	[T]	[CLV]	[KS]	[KNR]	[IL]	x
Conservation:	-0.459	-0.234	-1.030	-0.511	-0.504	-0.035	-0.749	-0.355	-0.108	0.630	-0.926	-0.615	0.218	-0.207	-0.148	-0.304	2.032	-0.563	-0.126	-0.226	1.098	-0.771	-0.667	3.900	1.098	1.098	-0.459	-0.083	-0.200	0.187	-0.978

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1eke_A_188	1eke	A	189	219	KTIKFLEDYFKKHKKLPDIARTHWKTCKRIL	HHHHHHHHHHHHHSS--TTB-TTSHHHHHHH	aaaaaaaaaaaaavbxxaaxxaaxaaaaaaa
1i39_A_168	1i39	A	168	198	PRTREVLKEWIASGRIPSCVRMRWKTVSNLR	HHHHHHHHHHHHHT---TTB-TTSHHHHHHH	aaaaaaaaaaaaavbxpaaxxaaxaaaaaaa
1io2_A_174	1io2	A	175	205	RTRAFLENYYREHGEFPPIVRKGWKTLKKIA	HHHHHHHHHHHHHSS--TTB-TT-HHHHHHH	aaaaaaaaaaaaavbxxaaxxaaxaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1eke_A_188	1eke	A	MSESELENOMETHIONINE	R - 209
1eke_A_188	1eke	A	MSESELENOMETHIONINE	H - 211
1eke_A_188	1eke	A	MES2-(N-MORPHOLINO)-ETHANESULFONIC ACID	H - 211
1eke_A_188	1eke	A	MSESELENOMETHIONINE	W - 212
1eke_A_188	1eke	A	MES2-(N-MORPHOLINO)-ETHANESULFONIC ACID	W - 212
1eke_A_188	1eke	A	MES2-(N-MORPHOLINO)-ETHANESULFONIC ACID	K - 213
1eke_A_188	1eke	A	MES2-(N-MORPHOLINO)-ETHANESULFONIC ACID	T - 214

Clusters included in this Subclass