ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 12.2.1

Subclass Accession number: 5137
Subclass: 12.2.1

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 2.5 (>75 %)  2.5 (>75 %)  2.5.1 (>75 %)  2.5.1 (>75 %)  2.5.1.18 (>75 %)  2.5.1.18
GO : GO:0004364 (>75 %)  GO:0004364 (>75 %)  GO:0016765 (>75 %)  GO:0016765 (>75 %)
SCOP : 47615 (>75 %)  47615 (>75 %)  47616 (>75 %)  47616 (>75 %)  47617 (>75 %)  47617 (>75 %)

Number of loops: 4

Average sequence ID (%) : 24.3 +/- 20.2
Average RMSD (Å) : 0.800 +/- 0.283

Consensus geometry

d (Å): 13

delta (°): 45-90

theta (°): 135-180

rho (°): 180-225

Consensus Sequence:	hhXXpXhhhhXphThh
(φψ)-conformation:	aaeapabaaeabpbaa

Pattern:	[AL]	[KP]	x	[ALMT]	[LM]	[DKQ]	x	[LWY]	[DES]	[DQT]	[FY]	[LV]	[GT]	[EGK]	[NQR]	[AEP]	[WY]	[AFL]	x	[AG]	x	[HKS]	[ILV]	[ST]	[FHVW]	[AV]	[D]	[FI]	[CIMY]	[ALVW]	x	x	[ACTV]	x	[DET]
Conservation:	-0.028	1.023	-1.100	-0.754	0.886	-0.089	-0.842	-0.214	-0.011	-0.322	1.993	0.534	0.393	-0.474	0.130	-0.372	2.407	-0.634	-1.144	0.915	-0.732	-0.387	0.524	0.922	-0.884	0.034	2.797	0.915	-0.711	-1.057	-0.758	-1.403	-0.581	-0.771	-0.204

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1hna_*_119	1hna	-	130	164	LPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLE	HHHHHHHHHHHHTT-SBTTBSS--HHHHHHHHHHH	aaaaaaaaaaaaeaxabaaeabxbaaaaaaaaaaa
1iyh_A_124	1iyh	A	124	158	APHLMQDLDTYLGGREWLIGMSVTWADFYWEICST	HHHHHHHHHHHHTT-SSSSTTS--HHHHHHHHHHH	aaaaaaaaaaaaeaxababeabxbaaaaaaaaaaa
1v2a_A_124	1v2a	A	128	162	LKGALDLLEQFVTERAYAAADHLTVADICLLGTVT	HHHHHHHHHHHHHHSSSSSSSS--HHHHHHHHHHH	aaaaaaaaaaaaaababaababxbaaaaaaaaaaa
2fhe_A_114	2fhe	A	125	159	LPTTMKMWSDFLGKNPYLRGTSVSHVDFMVYEALD	HHHHHHHHHHHHTT-SBTTBSS--HHHHHHHHHHH	aaaaaaaaaaaaeaxabaaeabxbaaaaaaaaaaa

Clusters included in this Subclass