ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 12.7.1

Subclass Accession number: 5142
Subclass: 12.7.1

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 2.3 (>50 %)  2.3.3 (>50 %)  2.3.3.1
GO : GO:0004108 (>75 %)  GO:0016746 (>75 %)  GO:0046912 (>75 %)
SCOP : 48255 (>75 %)  48256 (>75 %)  48257 (>75 %)

Number of loops: 3

Average sequence ID (%) : 34.7 +/- 15.5
Average RMSD (Å) : 0.567 +/- 0.058

Consensus geometry

d (Å): 25

delta (°): 135-180

theta (°): 0-45

rho (°): 225-270

Consensus Sequence:	pXGXXhhXPppcLppX
(φψ)-conformation:	aalbppbppbaabpaa

Pattern:	[P]	[ER]	x	x	x	x	[AIK]	[AG]	[FIM]	[RS]	[LV]	[LT]	[AS]	[KT]	[FIM]	[P]	[ST]	[IMV]	[AV]	[A]	x	[CDW]	[QY]	[KR]	x	[KRS]	x	[G]	x	[EP]	[FLY]	[IV]	x	[P]	[KR]	[EN]	[DK]	[L]	[DS]	[HY]	[AS]	[AG]	[N]	[F]	[L]	[NWY]	[M]	[LMT]	[FH]
Conservation:	2.321	-0.050	-0.831	-1.316	-1.255	-1.376	-1.316	-0.184	-0.467	-0.518	-0.081	-0.515	-0.083	-0.296	-0.467	2.321	0.138	-0.104	-0.339	0.685	-1.013	-1.013	0.137	0.462	-1.255	-0.528	-1.316	1.776	-1.013	-0.152	-0.225	0.430	-1.073	2.321	0.465	0.027	-0.086	0.685	-0.183	1.121	-0.078	-0.185	1.776	1.776	0.685	-0.528	1.230	-0.649	0.141

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1a59_*_116	1a59	-	116	164	PEANLEKAMSLLATFPSVVAYDQRRRRGEELIEPREDLDYSANFLWMTF	HHHHHHHHHHHHHHHHHHHHHHHHHHTT-------TTS-HHHHHHHHHH	aaaaaaaaaaaaaaaaaaaaaaaaaaavbbxbxxbaabxaaaaaaaaaa
1aj8_A_118	1aj8	A	118	166	PEEVYRIGISVTAKIPTIVANWYRIKNGLEYVPPKEKLSHAANFLYMLH	HHHHHHHHHHHHHHHHHHHHHHHHHHTT-------TTS-HHHHHHHHHH	aaaaaaaaaaaaaaaaaaaaaaaaaaavxxxbwxbaaxxaaaaaaaaaa
1k3p_A_154	1k3p	A	154	202	PRHREIAAFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAGNFLNMMF	HHHHHHHHHHHHHHHHHHHHHHHHHHHT-------TTS-HHHHHHHHHH	aaaaaaaaaaaaaaaaaaaaaaaaaaavbxxbxxbaabxaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Clusters included in this Subclass