ArchDB - Biological DataBase of Protein Loops

Grup de Recerca en Informàtica Biomèdica

Information on SUBCLASS 2.1.25

Subclass Accession number: 5345
Subclass: 2.1.25

PSSM

Type: HE alpha-beta
DB: ArchDB95

Image coordinates:

Rasmol PDB

Jmol PDB

Consensus coordinates:

Rasmol PDB

Jmol PDB

Conserved Annotation
GO : GO:0046914 (>50 %)

Number of loops: 3

Average sequence ID (%) : 11.1 +/- 12.7
Average RMSD (Å) : 0.733 +/- 0.115

Consensus geometry

d (Å): 9

delta (°): 135-180

theta (°): 90-135

rho (°): 135-180

Consensus Sequence:	hXhhXX
(φψ)-conformation:	aalpbp

Pattern:	x	[AM]	x	x	[FRY]	[ITY]	[EQS]	[AV]	[KL]	[AG]	[FY]	[TV]	x	[GSV]	[DGN]	x	x	[DPV]	[GIT]	x	[CIM]
Conservation:	-0.601	0.327	-0.698	-0.988	0.075	-0.505	0.462	0.616	-0.021	1.403	3.118	0.983	-0.037	-0.891	0.462	-0.408	-0.891	-0.795	-1.181	-0.698	0.268

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1ghe_A_136	1ghe	A	136	156	VAEAFYSALAYTRVGELPGYC	HHHHHHHHTT-EEEEEEEEEE	aaaaaaaaavxxxaebbxlab
1gx1_A_73	1gx1	A	79	99	EAWRRIQAKGYTLGNVDVTII	HHHHHHHHTT-EEEEEEEEEE	aaaaaaaaavxbxabbbbbxb
1kw3_B_153	1kw3	B	156	176	AMAFYTEVLGFVLSDIIDIQM	HHHHHHHTT--EEEEEEEEEE	aaaaaaaaavxbxabbbxxxa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1ghe_A_136	1ghe	A	ACOACETYL COENZYME *A	V - 136
1ghe_A_136	1ghe	A	ACOACETYL COENZYME *A	A - 137
1ghe_A_136	1ghe	A	ACOACETYL COENZYME *A	A - 139
1ghe_A_136	1ghe	A	MSESELENOMETHIONINE	F - 140
1ghe_A_136	1ghe	A	ACOACETYL COENZYME *A	F - 140
1ghe_A_136	1ghe	A	MSESELENOMETHIONINE	Y - 141
1ghe_A_136	1ghe	A	ACOACETYL COENZYME *A	Y - 141
1ghe_A_136	1ghe	A	ACOACETYL COENZYME *A	A - 143
1ghe_A_136	1ghe	A	MSESELENOMETHIONINE	L - 144
1ghe_A_136	1ghe	A	ACOACETYL COENZYME *A	L - 144
1ghe_A_136	1ghe	A	MSESELENOMETHIONINE	Y - 146
1ghe_A_136	1ghe	A	MSESELENOMETHIONINE	A - 157
1gx1_A_73	1gx1	A	MSESELENOMETHIONINE	G - 92
1gx1_A_73	1gx1	A	MSESELENOMETHIONINE	N - 93
1gx1_A_73	1gx1	A	MSESELENOMETHIONINE	I - 98
1gx1_A_73	1gx1	A	CDFCYTIDINE-5'-DIPHOSPHATE	I - 98
1gx1_A_73	1gx1	A	CDFCYTIDINE-5'-DIPHOSPHATE	I - 99

Clusters included in this Subclass

CLUSTER: HE.4.176