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Information on SUBCLASS 3.4.2
Subclass Accession number: 5488
Subclass: 3.4.2 PSSM
Type: HE alpha-beta
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 39

Average sequence ID (%) : 13.0 +/- 14.5
Average RMSD (Å) : 0.631 +/- 0.273

Consensus geometry
d (Å): 9 delta (°): 90-135 theta (°): 135-180 rho (°): 90-135
Consensus Sequence: XXXXphX
(φψ)-conformation: aabaabb
Pattern: x[fhilmvw]xxxx[knprst][dehknqrst][acfgiltv][dehknprst][afgilmptv]x
Conservation:-1.5511.008-0.443-0.209-0.350-0.9322.1611.113-0.181-0.6150.117-0.116
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a4y_A_4401a4y   A448459ALEKDKPSLRVIHHHHH-TT-EEEaaaaabaabxbx
1b3t_A_5141b3t   A523533GTALAIPQCRL.HHHHH-TT-EE.aaaaabaabbb.
1b63_A_1641b63   A177188RIALARFDVTINHHHHH-TT-EEEaaaaabaabxbb
1b74_A_121b74   A1829AIRNRYRKVDIVHHHHHSSS-EEEaaaaabaapxbb
1cjc_A_161cjc   A2435HLLKHHSRAHVDHHHHH-SS-EEEaaaaabaapbbb
1cza_N_8711cza   N878889TVKELSPKCNVSHHHHHSTTEEEEaaaaabaabbbb
1d2k_A_1071d2k   A114125LLKKNNRNLKTLHHHHH-TT-EEEaaaaabaaxbbb
1e8c_A_2431e8c   A247258RWLAKLPDAVAVHHHTT-TT-EEEaaaaabaaxbxb
1ek6_A_1561ek6   A170181DLCQADKTWNAVHHHHH-TT-EEEaaaaabaaxbbb
1euc_A_1091euc   A117128HRLLRQGKTRLIHHHTT-SS-EEEaaaaabaabxbb
1f9m_A_471f9m   A5869KLAEEYLDVIFLHHHHH-TTSEEEaaaaabaabxbb
1gh2_A_351gh2   A4657SMSNKYPQAVFLHHHHH-TTSEEEaaaaabaabbbb
1gpe_A_341gpe   A4152AKLTENPKIKVLHHHHTSTT--EEaaaaaxaaxxbb
1gpu_A_5041gpu   A512523KNSLESKHTPSIHHHHH-SS--EEaaaaaxaabwbb
1h7w_A_6181h7w   A627638ELKADFPDNIVIHHHHH-TTSEEEaaaaabaaxxbb
1i6a_A_1021i6a   A112123MLHQTFPKLEMYHHHHH-TTEEEEaaaaabaaxbxb
1itz_A_5091itz   A517528KVAVLNRKRPSIHHHHH-TTS-EEaaaaaxaabxbb
1ixc_A_1051ixc   A112123AFLTSTPTATVSHHHHH-TTEEEEaaaaabaaxbbb
1k4k_A_531k4k   A6272LAIADKPLFTL.HHHTT-TTEEE.aaaaabaabbb.
1lam_*_1801lam   -190201NLKSASIKTDVFHHHHH-SSEEEEaaaaabaabbbb
1lu4_A_10371lu4   A10481059QVAAANPAVTFVHHHHH-TTSEEEaaaaabaabxxb
1mu2_A_1561mu2   A170181PFRKANKDVIIIHHHHH-TTSEEEaaaaabaaxxbb
1ne9_A_311ne9   A3142GWAKVKNNWEPVHHHHHTTTSEEEaaaaaxaabxwb
1ny5_A_591ny5   A6576WIKERSPETEVIHHHHH-TTSEEEaaaaabaaxxbb
1oc2_A_151oc2   A2334YVYNNHPDVHVTHHHHH-TT-EEEaaaaabaaxxbb
1px0_A_381px0   A4353AFAETYPQLKP.HHHHH-TTSEE.aaaaabaabbx.
1qtr_A_2731qtr   A278289DLAKAWPEAELHHHHHH-TTSEEEaaaaabaaxxxb
1qzz_A_1951qzz   A199210AIALRAPHLRGTHHHHH-TT-EEEaaaaabaaxbbb
1r26_A_371r26   A4253KIAYEFPTVKFAHHHHH-TTSEEEaaaaabaabxbb
1rjd_A_1121rjd   A114125PLLQMFPHLAYVHHHHH-TTEEEEaaaaabaaxbbb
1s4q_A_341s4q   A4050CLRERIPNLHF.HHHHHSTT-EE.aaaaabaaxxx.
1thg_*_4291thg   -434445VMLSATKDVNRWHHHHH-TTS-EEaaaaaxaabxbb
1udb_*_1481udb   -162173DLQKAQPDWSIAHHHHHSTT-EEEaaaaabaaxbbx
1v6s_A_711v6s   A7686ALRAHLPEARF.HHHHH-TTEEE.aaaaabaaxbb.
1vrt_A_1561vrt   A170181PFRKQNPDIVIYHHHHH-TT-EEEaaaaabaaxbbb
1xaa_*_1901xaa   -201212EVGRGYPDVALEHHHTT-TTSEEEaaaaabaabxbb
1zpd_A_5151zpd   A523534KVALANTDGPTLHHHHH--SS-EEaaaaaxaabxbx
2bce_*_3942bce   -403414QHKSHAKSANTYHHHHH-SS--EEaaaaapaabxbb
2bnh_*_4362bnh   -444455ALEGSKPGLRVIHHHHH-SS-EEEaaaaabaabbbx
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1b63_A_1641b63   A     EDO1,2-ETHANEDIOL R - 177
1b63_A_1641b63   A     EDO1,2-ETHANEDIOL I - 178
1b63_A_1641b63   A     EDO1,2-ETHANEDIOL A - 181
1b74_A_121b74   A     DGND-GLUTAMINE G - 12
1b74_A_121b74   A     DGND-GLUTAMINE T - 14
1b74_A_121b74   A     DGND-GLUTAMINE V - 15
1cjc_A_161cjc   A     FADFLAVIN-ADENINE DINUCLEOTIDE P - 16
1cjc_A_161cjc   A     FADFLAVIN-ADENINE DINUCLEOTIDE A - 17
1cjc_A_161cjc   A     FADFLAVIN-ADENINE DINUCLEOTIDE G - 18
1cjc_A_161cjc   A     FADFLAVIN-ADENINE DINUCLEOTIDE Y - 37
1e8c_A_2431e8c   A     KCXLYSINE NZ-CARBOXYLIC ACID W - 248
1e8c_A_2431e8c   A     MSESELENOMETHIONINE V - 258
1ek6_A_1561ek6   A     NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE Y - 157
1ek6_A_1561ek6   A     UPGURIDINE-5'-DIPHOSPHATE-GLUCOSE Y - 157
1ek6_A_1561ek6   A     NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE K - 161
1ek6_A_1561ek6   A     MGMAGNESIUM ION Q - 173
1ek6_A_1561ek6   A     MGMAGNESIUM ION A - 174
1ek6_A_1561ek6   A     MGMAGNESIUM ION K - 176
1ek6_A_1561ek6   A     NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE Y - 185
1ek6_A_1561ek6   A     UPGURIDINE-5'-DIPHOSPHATE-GLUCOSE Y - 185
1gpe_A_341gpe   A     FADFLAVIN-ADENINE DINUCLEOTIDE L - 34
1gpe_A_341gpe   A     FADFLAVIN-ADENINE DINUCLEOTIDE T - 35
1gpe_A_341gpe   A     FADFLAVIN-ADENINE DINUCLEOTIDE G - 36
1gpe_A_341gpe   A     FADFLAVIN-ADENINE DINUCLEOTIDE I - 54
1gpe_A_341gpe   A     FADFLAVIN-ADENINE DINUCLEOTIDE E - 55
1h7w_A_6181h7w   A     FMNFLAVIN MONONUCLEOTIDE S - 640
1ixc_A_1051ixc   A     MSESELENOMETHIONINE T - 125
1k4k_A_531k4k   A     XEXENON L - 60
1k4k_A_531k4k   A     XEXENON A - 63
1k4k_A_531k4k   A     XEXENON I - 64
1k4k_A_531k4k   A     XEXENON F - 70
1mu2_A_1561mu2   A     GOLGLYCEROL I - 179
1mu2_A_1561mu2   A     GOLGLYCEROL I - 181
1ny5_A_591ny5   A     PO4PHOSPHATE ION E - 72
1ny5_A_591ny5   A     PO4PHOSPHATE ION T - 73
1oc2_A_151oc2   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE F - 15
1oc2_A_151oc2   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE I - 16
1oc2_A_151oc2   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE G - 17
1oc2_A_151oc2   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE L - 36
1oc2_A_151oc2   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE D - 37
1qzz_A_1951qzz   A     ACTACETATE ION G - 195
1qzz_A_1951qzz   A     SAMS-ADENOSYLMETHIONINE G - 195
1qzz_A_1951qzz   A     ACTACETATE ION M - 196
1qzz_A_1951qzz   A     SAMS-ADENOSYLMETHIONINE M - 196
1qzz_A_1951qzz   A     ACTACETATE ION L - 197
1qzz_A_1951qzz   A     ACTACETATE ION A - 198
1qzz_A_1951qzz   A     ACTACETATE ION L - 211
1qzz_A_1951qzz   A     SAMS-ADENOSYLMETHIONINE V - 212
1qzz_A_1951qzz   A     SAMS-ADENOSYLMETHIONINE E - 213
1rjd_A_1121rjd   A     SAMS-ADENOSYLMETHIONINE I - 127
1rjd_A_1121rjd   A     SAMS-ADENOSYLMETHIONINE D - 128
1s4q_A_341s4q   A     FMTFORMIC ACID K - 34
1s4q_A_341s4q   A     FMTFORMIC ACID S - 35
1s4q_A_341s4q   A     FMTFORMIC ACID T - 36
1udb_*_1481udb   *     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE Y - 149
1udb_*_1481udb   *     UFGURIDINE-5'-DIPHOSPHATE-4-DEOXY-4-FLUORO-ALPHA-D-GALACTOSE Y - 149
1udb_*_1481udb   *     UFGURIDINE-5'-DIPHOSPHATE-4-DEOXY-4-FLUORO-ALPHA-D-GALACTOSE G - 150
1udb_*_1481udb   *     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE K - 153
1udb_*_1481udb   *     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE Y - 177
1udb_*_1481udb   *     UFGURIDINE-5'-DIPHOSPHATE-4-DEOXY-4-FLUORO-ALPHA-D-GALACTOSE Y - 177
1vrt_A_1561vrt   A     NEVNEVIRAPINE V - 179
1vrt_A_1561vrt   A     NEVNEVIRAPINE I - 180
1vrt_A_1561vrt   A     NEVNEVIRAPINE Y - 181
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1oc2_A_151oc2   A AC4NAH BINDING SITE FOR CHAIN AF - 15
1oc2_A_151oc2   A AC4NAH BINDING SITE FOR CHAIN AI - 16
1oc2_A_151oc2   A AC4NAH BINDING SITE FOR CHAIN AD - 37

Clusters included in this Subclass
CLUSTER: HE.2.85
CLUSTER: HE.3.24
CLUSTER: HE.4.25
CLUSTER: HE.5.11