ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 4.3.6

Subclass Accession number: 5609
Subclass: 4.3.6

Type: HE alpha-beta
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : - (>75 %) 1 (>75 %) 2.7 (>75 %) 2.7.1 (>75 %) 2.7.1.40 3 (>75 %)
SCOP : 52934 (>75 %) 52935 (>75 %) 52936 (>75 %) 53473 (>75 %) 53474 (>75 %)

Number of loops: 5

Average sequence ID (%) : 18.0 +/- 17.0
Average RMSD (Å) : 0.880 +/- 0.192

Consensus geometry

d (Å): 13

delta (°): 45-90

theta (°): 135-180

rho (°): 90-135

Consensus Sequence:	XchXXPhh
(φψ)-conformation:	aapabpbb

Pattern:	[flt]	[ADET]	[dkry]	[ILV]	[AEGK]	[GKN]	[CILT]	[ADPST]	[KTV]	[P]	[ALTV]	[il]	[AILV]	[AFITV]	x
Conservation:	-0.575	-0.152	-0.954	0.779	-0.346	0.189	-0.155	-0.413	-0.301	3.328	-0.152	-0.169	-0.031	-0.436	-0.611

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1a8s_*_206	1a8s	-	206	220	TEDLKKIDVPTLVVH	HHHHHT--S-EEEEE	aaaaaaxabpbxbbb
1dci_A_134	1dci	A	152	166	FTVIEKCPKPVIAAI	HHHHHHSSS-EEEEE	aaaaaaxaxwbbxbx
1hyu_A_4	1hyu	A	11	25	RAYLEKLTKPVELIA	HHHHTT--S-EEEEE	aaaaaapabxbbxbx
1ju3_A_241	1ju3	A	241	255	FERLGGLATPALITA	HHHHTT----EEEEE	aaaaaaxabwbxxbb
1tht_A_189	1tht	A	193	207	LDKVANTSVPLIAFT	HHHHTT--S-EEEEE	aaaaaaxaxpbbbxb

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1dci_A_134	1dci	A	EDO1,2-ETHANEDIOL	L - 144
1dci_A_134	1dci	A	EDO1,2-ETHANEDIOL	I - 145
1dci_A_134	1dci	A	EDO1,2-ETHANEDIOL	Y - 148
1dci_A_134	1dci	A	EDO1,2-ETHANEDIOL	Q - 149
1dci_A_134	1dci	A	EDO1,2-ETHANEDIOL	E - 156

Clusters included in this Subclass

CLUSTER: HE.5.274

CLUSTER: HE.6.257

CLUSTER: HE.7.144