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Information on SUBCLASS 1.1.5
Subclass Accession number: 66
Subclass: 1.1.5 PSSM
Type: HE alpha-beta
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 3.1 (>75 %)  3.1.1 (>75 %)  
GO : GO:0004091 (>50 %)  GO:0016788 (>75 %)  GO:0016789 (>75 %)  
SCOP : 53473 (>75 %)  53474 (>75 %)  53475 (>75 %)  
 Number of loops: 43

Average sequence ID (%) : 16.5 +/- 17.9
Average RMSD (Å) : 0.435 +/- 0.146

Consensus geometry
d (Å): 9 delta (°): 90-135 theta (°): 135-180 rho (°): 180-225
Consensus Sequence: XXXXX
(φψ)-conformation: aalbb
Pattern: [aeknst]xxx[DEGKNQR][acdgstv]x[acfgilptv]x
Conservation:1.192-0.413-0.395-0.9291.846-0.655-0.9450.705-0.404
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1amf_*_141amf   -2533KKEKGVDVVHHHH--EEEaaaavxxbb
1bu6_O_4161bu6   O423431SDILGTRVEHHHHTSEEEaaaavbxbx
1dbx_A_1411dbx   A145153AKVLGAEFTHHHHT-EEEaaaavxbxb
1e4f_T_3441e4f   T349357TEVFKSPVRHHHH-S-EEaaaalbxbb
1ea5_A_1331ea5   A136144AYTEEVVLVHHHHT-EEEaaaalbxbb
1f89_A_1991f89   A212220AVDNQVYVMHHHHTSEEEaaaalbxbb
1fo6_A_791fo6   A8593AAELGIGFNHHHHT-EEEaaaavbxbb
1g3q_A_1821g3q   A186194EDVMEVPLLHHHH-S-EEaaaavbpxa
1g61_A_20341g61   A20412049SEVLETKCLHHHHT-EEEaaaalbxbb
1g61_A_21281g61   A21322140EDSLNVEVEHHHH-SEEEaaaavbpbb
1g62_A_1231g62   A130138SDVLGVEVFHHHHTSEEEaaaalbxbb
1g62_A_1671g62   A174182SSLLQVPLVHHHHTS-EEaaaavbwbb
1gef_A_591gef   A6977SRRFGGIPVHHHHT-EEEaaaagbxwb
1gpj_A_2011gpj   A208215ARDLGGEA.HHHHT-EE.aaaavbbx.
1i39_A_1081i39   A115123EEITGLRVVHHHH-SEEEaaaavbxbb
1i58_A_3651i58   A373381AKKMNKEVNHHHTT--EEaaaalbbbx
1j0a_A_281j0a   A3139SREIGADVYHHHHTSEEEaaaavbxbb
1j31_A_1831j31   A185193ALENRVYTIHHHHT-EEEaaaalbxbb
1jg1_A_1041jg1   A110118SEIVKTDVYHHHH-S-EEaaaavbpbb
1jj2_R_341jj2   R4250EEQYDVTVEHHHHT--EEaaaalbbxa
1jwq_A_1021jwq   A113121APATGLTDRHHHH-S-EEaaaavxpxa
1k47_A_1501k47   A153161CIAAEDLVLHHHHTS-EEaaaalbxbb
1kyh_A_1681kyh   A176184AAQLQTVIVHHHHTSEEEaaaavbxbb
1lh0_A_11661lh0   A11711179ERDYGCKVIHHHH--EEEaaaalbbxx
1mx1_A_11551mx1   A11581166AAHENVVVVHHHHT-EEEaaaalbxbb
1n0w_A_2531n0w   A256264ADEFGVAVVHHHH--EEEaaaavxxbb
1n62_B_2791n62   B288296SIVLGVPVKHHHHSS-EEaaaavbxbx
1o9p_A_1571o9p   A160168AAYCGTAAIHHHHT-EEEaaaavbxbb
1obd_A_1271obd   A133139YVKTGTV..HHHHSEE..aaaavbb..
1obr_*_2271obr   -241249AQTNGYTPQHHHH--EEEaaaavxbxb
1oj4_A_1421oj4   A144152VFVRGHAAFHHHH-B-EEaaaavbpbx
1pfk_A_1391pfk   A157165SSSHQRISVHHHHT-EEEaaaalbbbb
1pfk_A_2271pfk   A235243EKETGRETRHHHHSS-EEaaaavbxbb
1qe3_A_1211qe3   A124132AAQGEVIVVHHHHT-EEEaaaalbxbb
1qlm_A_191qlm   A1927AELLNVEVQHHHHT-EEEaaaalbbbb
1qz3_A_941qz3   A101109AKDGRAVVFHHHHTSEEEaaaalbxbb
1sbp_*_141sbp   -2937KQETGDNVVHHHHS-EEEaaaavxbbb
1toa_A_2031toa   A206214SRAYGFEVKHHHHT-EEEaaaavbbbb
1urs_A_401urs   A5462AKAHGDKVIHHHH--EEEaaaagxxbb
1v8a_A_1441v8a   A155163AREFNTTVAHHHTTSEEEaaaalbxbb
1vjo_A_1691vjo   A173181CREFGTLLLHHHHT-EEEaaaavbxxb
2bce_*_1282bce   -131139ATRGNVIVVHHHHT-EEEaaaalbxbb
2fok_A_5282fok   A536544NHITNCNGAHHHH--EEEaaaavxxbb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1amf_*_141amf   *     MOOMOLYBDATE ION A - 37
1g3q_A_1821g3q   A     ADPADENOSINE-5'-DIPHOSPHATE I - 197
1g3q_A_1821g3q   A     ADPADENOSINE-5'-DIPHOSPHATE P - 198
1j31_A_1831j31   A     MSESELENOMETHIONINE I - 183
1j31_A_1831j31   A     MSESELENOMETHIONINE R - 184
1j31_A_1831j31   A     MSESELENOMETHIONINE A - 185
1j31_A_1831j31   A     MSESELENOMETHIONINE L - 186
1j31_A_1831j31   A     MSESELENOMETHIONINE T - 192
1j31_A_1831j31   A     MSESELENOMETHIONINE I - 193
1j31_A_1831j31   A     MSESELENOMETHIONINE T - 194
1jg1_A_1041jg1   A     SAHS-ADENOSYL-L-HOMOCYSTEINE W - 104
1jg1_A_1041jg1   A     SAHS-ADENOSYL-L-HOMOCYSTEINE N - 105
1jg1_A_1041jg1   A     SAHS-ADENOSYL-L-HOMOCYSTEINE A - 106
1jg1_A_1041jg1   A     SAHS-ADENOSYL-L-HOMOCYSTEINE I - 120
1jg1_A_1041jg1   A     SAHS-ADENOSYL-L-HOMOCYSTEINE E - 121
1jj2_R_341jj2   R     MGMAGNESIUM ION K - 34
1jj2_R_341jj2   R     MGMAGNESIUM ION T - 54
1jj2_R_341jj2   R     MGMAGNESIUM ION Q - 55
1kyh_A_1681kyh   A     MSESELENOMETHIONINE W - 175
1kyh_A_1681kyh   A     MSESELENOMETHIONINE L - 179
1kyh_A_1681kyh   A     MSESELENOMETHIONINE T - 181
1n0w_A_2531n0w   A     MSESELENOMETHIONINE L - 253
1n0w_A_2531n0w   A     MSESELENOMETHIONINE R - 254
1n0w_A_2531n0w   A     MSESELENOMETHIONINE L - 255
1n0w_A_2531n0w   A     MSESELENOMETHIONINE A - 256
1n0w_A_2531n0w   A     MSESELENOMETHIONINE F - 259
1n0w_A_2531n0w   A     MSESELENOMETHIONINE V - 261
1n0w_A_2531n0w   A     MSESELENOMETHIONINE V - 264
1n0w_A_2531n0w   A     MSESELENOMETHIONINE I - 265
1n0w_A_2531n0w   A     EDO1,2-ETHANEDIOL I - 265
1o9p_A_1571o9p   A     MLAMALONIC ACID R - 158
1oj4_A_1421oj4   A     MSESELENOMETHIONINE V - 142
1oj4_A_1421oj4   A     MSESELENOMETHIONINE V - 146
1oj4_A_1421oj4   A     MSESELENOMETHIONINE R - 147
1pfk_A_1391pfk   A     ADPADENOSINE-5'-DIPHOSPHATE R - 154
1pfk_A_1391pfk   A     MGMAGNESIUM ION R - 154
1pfk_A_1391pfk   A     ADPADENOSINE-5'-DIPHOSPHATE S - 158
1v8a_A_1441v8a   A     ZNZINC ION T - 165
1vjo_A_1691vjo   A     MSESELENOMETHIONINE L - 181
1vjo_A_1691vjo   A     MSESELENOMETHIONINE D - 183
1vjo_A_1691vjo   A     PLPPYRIDOXAL-5'-PHOSPHATE D - 183
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1obd_A_1271obd   A AC3SO4 BINDING SITE FOR CHAIN AG - 127
1obd_A_1271obd   A AC3SO4 BINDING SITE FOR CHAIN AS - 128
1oj4_A_1421oj4   A AC5CL BINDING SITE FOR CHAIN AR - 147

Clusters included in this Subclass
CLUSTER: HE.1.3
CLUSTER: HE.2.13
CLUSTER: HE.2.83
CLUSTER: HE.3.13
CLUSTER: HE.4.105