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Information on SUBCLASS 4.8.3
Subclass Accession number: 662
Subclass: 4.8.3 PSSM
Type: HA beta-beta hairpin
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 1.8 (>75 %)  1.8.1 (>75 %)  3.4 (>50 %)  3.4.23 (>50 %)  
GO : GO:0004175 (>50 %)  GO:0004190 (>50 %)  GO:0005489 (>75 %)  GO:0008233 (>50 %)  GO:0015036 (>75 %)  GO:0016667 (>75 %)  GO:0016668 (>75 %)  GO:0048037 (>75 %)  GO:0050660 (>75 %)  GO:0050662 (>75 %)  
SCOP : 50629 (>50 %)  50630 (>50 %)  50646 (>50 %)  55423 (>75 %)  55424 (>75 %)  55425 (>75 %)  
Number of loops: 3

Average sequence ID (%) : 22.8 +/- 21.0
Average RMSD (Å) : 0.400 +/- 0.173

Consensus geometry
d (Å): 5 delta (°): 90-135 theta (°): 135-180 rho (°): 270-315
Consensus Sequence: XVGpppXX
(φψ)-conformation: bbeaalpp
Pattern: [AFY][AVY][AGI][DQ][AFI]x[V][G][DES][HN][QR][AQ][KPQ]x[ST][FV]x[ILV]x
Conservation:-0.320-0.778-1.1590.604-0.854-0.9301.2812.654-0.0151.2330.669-0.082-0.320-1.2350.567-0.108-0.7780.366-0.796
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1j71_A_141j71   A1432YAADIVVGSNQQKQTVVIDEEEEEEETTTTEEEEEEEEbbbxbbbeaalxxbbbxxb
1lf2_A_151lf2   A1634FYGDAEVGDNQQPFTFILDEEEEEEETTTTEEEEEEEEbbbxbbbeaalxwbbbxxb
1oa8_A_6271oa8   A628646AVIQFAVGEHRAQVSVEVLEEEEEEETTTTEEEEEEEEbbbxbbxeaalxxbbbxbp
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1lf2_A_151lf2   A     R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE M - 15
1lf2_A_151lf2   A     R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE I - 32
1lf2_A_151lf2   A     R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE D - 34

Clusters included in this Subclass
CLUSTER: HA.3.149