ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 4.14.2

Subclass Accession number: 7369
Subclass: 4.14.2

Type: EH beta-alpha
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Number of loops: 3

Average sequence ID (%) : 37.3 +/- 16.7
Average RMSD (Å) : 0.367 +/- 0.058

Consensus geometry

d (Å): 7

delta (°): 45-90

theta (°): 135-180

rho (°): 135-180

Consensus Sequence:	hIpGXTXH
(φψ)-conformation:	bbpbabaa

Pattern:	[AV]	[IV]	[I]	[APT]	[IL]	[G]	[TV]	[LV]	[I]	[KR]	[G]	[AS]	[T]	[MPT]	[H]	[FY]	[DE]	[Y]	[IV]	[ACS]	[DNS]	[ES]	[ATV]	[AST]	[HK]	[AG]	[IL]	[AM]	[NQ]	[AL]	[AQS]	x	[EKT]	[LTV]
Conservation:	-0.539	0.270	0.542	-0.976	-0.001	1.680	-0.456	-0.272	0.542	0.300	1.680	-0.269	1.111	-1.165	2.818	0.953	0.514	2.249	0.270	-0.660	-0.470	-0.325	-0.913	-0.660	-0.254	-0.111	-0.001	-0.723	-0.035	-0.815	-0.913	-1.545	-0.913	-0.913

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1ejb_A_83	1ejb	A	83	116	VVIPIGVLIKGSTMHFEYISDSTTHALMNLQEKV	EEEEEEEEE--SSSHHHHHHHHHHHHHHHHHHHH	bbbwbbbbbpbaxaaaaaaaaaaaaaaaaaaaaa
1hqk_A_74	1hqk	A	74	107	AVIAIGVLIRGATPHFDYIASEVSKGLANLSLEL	EEEEEEEEE--SSTHHHHHHHHHHHHHHHHHHHH	bbbxbbbbbxbabaaaaaaaaaaaaaaaaaaaaa
1rvv_1_74	1rvv	1	74	107	AIITLGTVIRGATTHYDYVCNEAAKGIAQAANTT	EEEEEEEEE--SSSHHHHHHHHHHHHHHHHHHHH	bbbbbbbbbpbabaaaaaaaaaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1ejb_A_83	1ejb	A	INJ5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID	G - 88
1ejb_A_83	1ejb	A	INJ5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID	V - 89
1ejb_A_83	1ejb	A	INJ5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID	L - 90
1ejb_A_83	1ejb	A	INJ5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID	I - 91
1ejb_A_83	1ejb	A	INJ5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID	K - 92
1ejb_A_83	1ejb	A	INJ5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID	G - 93
1ejb_A_83	1ejb	A	INJ5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID	S - 94
1ejb_A_83	1ejb	A	INJ5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID	T - 95
1ejb_A_83	1ejb	A	INJ5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID	M - 96
1ejb_A_83	1ejb	A	INJ5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID	H - 97
1ejb_A_83	1ejb	A	INJ5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID	F - 98
1ejb_A_83	1ejb	A	INJ5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID	I - 101
1rvv_1_74	1rvv	1	INI5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE	G - 79
1rvv_1_74	1rvv	1	INI5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE	T - 80
1rvv_1_74	1rvv	1	INI5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE	V - 81
1rvv_1_74	1rvv	1	INI5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE	I - 82
1rvv_1_74	1rvv	1	PO4PHOSPHATE ION	I - 82
1rvv_1_74	1rvv	1	PO4PHOSPHATE ION	R - 83
1rvv_1_74	1rvv	1	PO4PHOSPHATE ION	G - 84
1rvv_1_74	1rvv	1	PO4PHOSPHATE ION	A - 85
1rvv_1_74	1rvv	1	PO4PHOSPHATE ION	T - 86
1rvv_1_74	1rvv	1	PO4PHOSPHATE ION	T - 87
1rvv_1_74	1rvv	1	INI5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE	H - 88
1rvv_1_74	1rvv	1	PO4PHOSPHATE ION	H - 88
1rvv_1_74	1rvv	1	INI5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE	Y - 89
1rvv_1_74	1rvv	1	PO4PHOSPHATE ION	Y - 89
1rvv_1_74	1rvv	1	INI5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE	V - 92

Clusters included in this Subclass

CLUSTER: EH.5.233

CLUSTER: EH.6.196