ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 6.5.1

Subclass Accession number: 7529
Subclass: 6.5.1

Type: EH beta-alpha
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Number of loops: 4

Average sequence ID (%) : 28.1 +/- 20.1
Average RMSD (Å) : 0.350 +/- 0.100

Consensus geometry

d (Å): 11

delta (°): 90-135

theta (°): 90-135

rho (°): 180-225

Consensus Sequence:	hGDGXhpphp
(φψ)-conformation:	bbaaaaapaa

Pattern:	[ACV]	x	[ACT]	[FLWY]	[FILY]	[G]	[DE]	[G]	[AE]	[AMT]	[ADNS]	[EQ]	[GPS]	[DEQ]	x	[FHK]
Conservation:	-0.470	-1.103	-0.371	-0.141	-0.390	2.069	1.097	2.069	-0.219	-0.677	-0.711	0.779	-0.534	0.229	-1.139	-0.488

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1l8a_A_224	1l8a	A	224	239	VYAFLGDGEMDEPESK	EEEEEETGGGGSHHHH	bbbxbbaaaaaxaaaa
1ni4_A_161	1ni4	A	161	176	CLTLYGDGAANQGQIF	EEEEEETTGGG-HHHH	bxbxbxaaaaaxaaaa
1ols_A_187	1ols	A	187	202	VICYFGEGAASEGDAH	EEEEEETTGGGSHHHH	bbbxbxaaaaaxaaaa
1qs0_A_207	1qs0	A	207	222	ASAWIGDGATAESDFH	EEEEEETGGGGSHHHH	bbxbbxaaaaaxaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1l8a_A_224	1l8a	A	TDPTHIAMIN DIPHOSPHATE	L - 228
1l8a_A_224	1l8a	A	TDPTHIAMIN DIPHOSPHATE	G - 229
1l8a_A_224	1l8a	A	MGMAGNESIUM ION	G - 229
1l8a_A_224	1l8a	A	TDPTHIAMIN DIPHOSPHATE	D - 230
1l8a_A_224	1l8a	A	MGMAGNESIUM ION	D - 230
1l8a_A_224	1l8a	A	TDPTHIAMIN DIPHOSPHATE	G - 231
1l8a_A_224	1l8a	A	MGMAGNESIUM ION	G - 231
1l8a_A_224	1l8a	A	TDPTHIAMIN DIPHOSPHATE	E - 232
1l8a_A_224	1l8a	A	TDPTHIAMIN DIPHOSPHATE	M - 233
1l8a_A_224	1l8a	A	TDPTHIAMIN DIPHOSPHATE	E - 235
1ni4_A_161	1ni4	A	MSESELENOMETHIONINE	Y - 165
1ni4_A_161	1ni4	A	TPPTHIAMINE DIPHOSPHATE	Y - 165
1ni4_A_161	1ni4	A	MGMAGNESIUM ION	G - 166
1ni4_A_161	1ni4	A	TPPTHIAMINE DIPHOSPHATE	G - 166
1ni4_A_161	1ni4	A	MSESELENOMETHIONINE	D - 167
1ni4_A_161	1ni4	A	MGMAGNESIUM ION	D - 167
1ni4_A_161	1ni4	A	TPPTHIAMINE DIPHOSPHATE	D - 167
1ni4_A_161	1ni4	A	MGMAGNESIUM ION	G - 168
1ni4_A_161	1ni4	A	TPPTHIAMINE DIPHOSPHATE	G - 168
1ni4_A_161	1ni4	A	TPPTHIAMINE DIPHOSPHATE	A - 169
1ni4_A_161	1ni4	A	TPPTHIAMINE DIPHOSPHATE	A - 170
1ni4_A_161	1ni4	A	MSESELENOMETHIONINE	Q - 172
1ni4_A_161	1ni4	A	TPPTHIAMINE DIPHOSPHATE	Q - 172
1ni4_A_161	1ni4	A	MSESELENOMETHIONINE	Q - 174
1ni4_A_161	1ni4	A	TPPTHIAMINE DIPHOSPHATE	Q - 174
1ni4_A_161	1ni4	A	MSESELENOMETHIONINE	F - 176
1ni4_A_161	1ni4	A	MSESELENOMETHIONINE	E - 177
1ni4_A_161	1ni4	A	MSESELENOMETHIONINE	A - 178
1ni4_A_161	1ni4	A	MSESELENOMETHIONINE	Y - 179
1ols_A_187	1ols	A	TDPTHIAMIN DIPHOSPHATE	F - 191
1ols_A_187	1ols	A	MNMANGANESE (II) ION	G - 192
1ols_A_187	1ols	A	TDPTHIAMIN DIPHOSPHATE	G - 192
1ols_A_187	1ols	A	MNMANGANESE (II) ION	E - 193
1ols_A_187	1ols	A	TDPTHIAMIN DIPHOSPHATE	E - 193
1ols_A_187	1ols	A	MNMANGANESE (II) ION	G - 194
1ols_A_187	1ols	A	TDPTHIAMIN DIPHOSPHATE	G - 194
1ols_A_187	1ols	A	TDPTHIAMIN DIPHOSPHATE	A - 195
1ols_A_187	1ols	A	TDPTHIAMIN DIPHOSPHATE	A - 196
1ols_A_187	1ols	A	TDPTHIAMIN DIPHOSPHATE	E - 198
1qs0_A_207	1qs0	A	MSESELENOMETHIONINE	A - 207
1qs0_A_207	1qs0	A	MSESELENOMETHIONINE	S - 208
1qs0_A_207	1qs0	A	MSESELENOMETHIONINE	A - 209
1qs0_A_207	1qs0	A	TDPTHIAMIN DIPHOSPHATE	I - 211
1qs0_A_207	1qs0	A	MGMAGNESIUM ION	G - 212
1qs0_A_207	1qs0	A	TDPTHIAMIN DIPHOSPHATE	G - 212
1qs0_A_207	1qs0	A	MGMAGNESIUM ION	D - 213
1qs0_A_207	1qs0	A	TDPTHIAMIN DIPHOSPHATE	D - 213
1qs0_A_207	1qs0	A	MGMAGNESIUM ION	G - 214
1qs0_A_207	1qs0	A	TDPTHIAMIN DIPHOSPHATE	G - 214
1qs0_A_207	1qs0	A	TDPTHIAMIN DIPHOSPHATE	A - 215
1qs0_A_207	1qs0	A	TDPTHIAMIN DIPHOSPHATE	T - 216
1qs0_A_207	1qs0	A	TDPTHIAMIN DIPHOSPHATE	E - 218
1qs0_A_207	1qs0	A	MSESELENOMETHIONINE	F - 227
1qs0_A_207	1qs0	A	MSESELENOMETHIONINE	Y - 231

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1ols_A_187	1ols	A	TDPTDP BINDING SITE FOR CHAIN A	G - 192
1ols_A_187	1ols	A	MN1MN BINDING SITE FOR CHAIN A	E - 193
1ols_A_187	1ols	A	TDPTDP BINDING SITE FOR CHAIN A	G - 194
1ols_A_187	1ols	A	TDPTDP BINDING SITE FOR CHAIN A	E - 198

Clusters included in this Subclass

CLUSTER: EH.5.118