ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 7.16.1

Subclass Accession number: 7591
Subclass: 7.16.1

Type: EH beta-alpha
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Number of loops: 3

Average sequence ID (%) : 23.2 +/- 21.3
Average RMSD (Å) : 0.333 +/- 0.153

Consensus geometry

d (Å): 17

delta (°): 45-90

theta (°): 135-180

rho (°): 270-315

Consensus Sequence:	hpXhhXphpcp
(φψ)-conformation:	bblaaaabpaa

Pattern:	[A]	[IMV]	[FIL]	[CL]	[KR]	x	[IV]	[CLM]	[HI]	[NY]	[FW]	[DST]	[DK]	[EKT]	[DKT]	[CQ]	x	[DER]	[FI]	[L]	[KRS]	[KNR]	[CF]
Conservation:	1.341	0.095	-0.384	-0.060	0.977	-1.630	0.952	-0.384	-0.222	-0.077	2.645	-0.671	0.075	-0.863	-1.151	0.231	-1.630	-0.576	-0.011	1.341	-0.576	-0.192	0.769

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1af7_*_224	1af7	-	226	248	AIFCRNVMIYFDKTTQEDILRRF	EEEE-SSGGGS-HHHHHHHHHHH	bbxbblaaaabxaaaaaaaaaaa
1fp1_D_268	1fp1	D	270	292	AMILKAVCHNWSDEKCIEFLSNC	EEEEESSGGGS-HHHHHHHHHHH	bbbbblaaaabxaaaaaaaaaaa
1fp2_A_249	1fp2	A	249	271	AVLLKYILHNWTDKDCLRILKKC	EEEEES-GGGS-HHHHHHHHHHH	bbbbblaaaabxaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1af7_*_224	1af7	*	SAHS-ADENOSYL-L-HOMOCYSTEINE	C - 229
1af7_*_224	1af7	*	SAHS-ADENOSYL-L-HOMOCYSTEINE	R - 230
1af7_*_224	1af7	*	SAHS-ADENOSYL-L-HOMOCYSTEINE	N - 231
1af7_*_224	1af7	*	SAHS-ADENOSYL-L-HOMOCYSTEINE	V - 232
1af7_*_224	1af7	*	SAHS-ADENOSYL-L-HOMOCYSTEINE	Y - 235
1af7_*_224	1af7	*	SAHS-ADENOSYL-L-HOMOCYSTEINE	F - 236
1af7_*_224	1af7	*	SAHS-ADENOSYL-L-HOMOCYSTEINE	I - 244
1fp1_D_268	1fp1	D	SAHS-ADENOSYL-L-HOMOCYSTEINE	L - 273
1fp1_D_268	1fp1	D	SAHS-ADENOSYL-L-HOMOCYSTEINE	K - 274
1fp1_D_268	1fp1	D	HCC2',4,4'-TRIHYDROXYCHALCONE	K - 274
1fp1_D_268	1fp1	D	SAHS-ADENOSYL-L-HOMOCYSTEINE	A - 275
1fp1_D_268	1fp1	D	HCC2',4,4'-TRIHYDROXYCHALCONE	A - 275
1fp1_D_268	1fp1	D	SAHS-ADENOSYL-L-HOMOCYSTEINE	V - 276
1fp1_D_268	1fp1	D	SAHS-ADENOSYL-L-HOMOCYSTEINE	H - 278
1fp1_D_268	1fp1	D	HCC2',4,4'-TRIHYDROXYCHALCONE	H - 278
1fp1_D_268	1fp1	D	SAHS-ADENOSYL-L-HOMOCYSTEINE	N - 279
1fp1_D_268	1fp1	D	HCC2',4,4'-TRIHYDROXYCHALCONE	N - 279
1fp1_D_268	1fp1	D	SAHS-ADENOSYL-L-HOMOCYSTEINE	W - 280
1fp2_A_249	1fp2	A	SAHS-ADENOSYL-L-HOMOCYSTEINE	L - 252
1fp2_A_249	1fp2	A	SAHS-ADENOSYL-L-HOMOCYSTEINE	K - 253
1fp2_A_249	1fp2	A	HMO4'-HYDROXY-7-METHOXYISOFLAVONE	K - 253
1fp2_A_249	1fp2	A	SAHS-ADENOSYL-L-HOMOCYSTEINE	Y - 254
1fp2_A_249	1fp2	A	HMO4'-HYDROXY-7-METHOXYISOFLAVONE	Y - 254
1fp2_A_249	1fp2	A	SAHS-ADENOSYL-L-HOMOCYSTEINE	I - 255
1fp2_A_249	1fp2	A	HMO4'-HYDROXY-7-METHOXYISOFLAVONE	I - 255
1fp2_A_249	1fp2	A	HMO4'-HYDROXY-7-METHOXYISOFLAVONE	H - 257
1fp2_A_249	1fp2	A	SAHS-ADENOSYL-L-HOMOCYSTEINE	N - 258
1fp2_A_249	1fp2	A	HMO4'-HYDROXY-7-METHOXYISOFLAVONE	N - 258
1fp2_A_249	1fp2	A	SAHS-ADENOSYL-L-HOMOCYSTEINE	W - 259

Clusters included in this Subclass

CLUSTER: EH.7.86