ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 12.4.1

Subclass Accession number: 7677
Subclass: 12.4.1

Type: EH beta-alpha
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Number of loops: 5

Average sequence ID (%) : 51.7 +/- 22.3
Average RMSD (Å) : 0.220 +/- 0.045

Consensus geometry

d (Å): 13

delta (°): 45-90

theta (°): 135-180

rho (°): 135-180

Consensus Sequence:	LHhChHNPTGhDPTXE
(φψ)-conformation:	bpablpbwalbbppaa

Pattern:	[IMV]	[FIV]	[LV]	[FL]	[H]	[AGS]	[C]	[AC]	[H]	[N]	[P]	[T]	[G]	[AILTV]	[DN]	[LP]	[RT]	x	[DE]	[Q]	[W]	[akv]	[EQT]	[IL]	[AV]	[DQS]	[AILV]	[ilmv]	[aek]	[EKRS]
Conservation:	-0.338	-0.586	-0.372	-0.400	1.595	-0.619	1.955	-0.164	1.595	0.874	1.234	0.514	0.874	-0.928	0.095	-0.432	-0.398	-1.287	0.082	0.514	2.675	-1.087	-0.611	-0.202	-0.474	-0.691	-0.719	-0.899	-1.087	-0.712

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1ajs_A_185	1ajs	A	185	214	IFVLHACAHNPTGTDPTPEQWKQIASVMKR	EEEEESSS-TTT-----HHHHHHHHHHHHH	xbxbxablpbwavbbxxaaaaaaaaaaaaa
1ars_*_185	1ars	-	185	214	VVLFHGCCHNPTGIDPTLEQWQTLAQLSVE	EEEEESSS-TTT-----HHHHHHHHHHHHH	xbxbxablpxwavbbxxaaaaaaaaaaaaa
1yaa_A_185	1yaa	A	185	214	IFVLHSCAHNPTGLDPTSEQWVQIVDAIAS	EEEEE-SS-TTT-----HHHHHHHHHHHHH	xbxbxablpbwavbbxxaaaaaaaaaaaaa
2ay1_A_185	2ay1	A	185	214	MVLLHGCCHNPTGANLTLDQWAEIASILEK	EEEEESSS-TTT-----HHHHHHHHHHHHH	bbxbxablpbwavxbxxaaaaaaaaaaaaa
7aat_A_185	7aat	A	185	214	IILLHACAHNPTGVDPRQEQWKELASVVKK	EEEEESSS-TTT-----HHHHHHHHHHHHH	bbxbxablpbwavxbxxaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1ajs_A_185	1ajs	A	PLA2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID	H - 189
1ajs_A_185	1ajs	A	PLA2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID	N - 194
1ars_*_185	1ars	*	PLPPYRIDOXAL-5'-PHOSPHATE	H - 189
1ars_*_185	1ars	*	PLPPYRIDOXAL-5'-PHOSPHATE	C - 192
1ars_*_185	1ars	*	PLPPYRIDOXAL-5'-PHOSPHATE	N - 194
1yaa_A_185	1yaa	A	MAEMALEIC ACID	N - 194
7aat_A_185	7aat	A	PLPPYRIDOXAL-5'-PHOSPHATE	A - 192

Clusters included in this Subclass