ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 12.2.1

Subclass Accession number: 8042
Subclass: 12.2.1

Type: HA beta-beta hairpin
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Number of loops: 15

Average sequence ID (%) : 35.4 +/- 25.1
Average RMSD (Å) : 0.660 +/- 0.272

Consensus geometry

d (Å): 3

delta (°): 45-90

theta (°): 135-180

rho (°): 225-270

Consensus Sequence:	XLGXppXXpXEXpppp
(φψ)-conformation:	bblpapaabppaapbb

Pattern:	[knqt]	[V]	[filtv]	[AL]	[G]	[AEKR]	[HTY]	[DNQSY]	[iltv]	x	[eknqrt]	[enpqrt]	[EG]	[deknprs]	[ehstw]	[ekqw]	[eqr]	x	[fily]	[DEKNPST]	[AIV]	x	[EKQR]	[afilpvy]	[FIV]	[ilpv]
Conservation:	-0.461	1.680	-0.449	0.856	2.956	-0.165	1.322	-0.074	-0.604	-0.775	-0.376	-1.058	0.994	-0.611	-0.661	-0.221	0.500	-1.209	-0.590	-0.382	0.893	-0.926	0.749	-1.030	0.488	-0.846

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1a5h_A_64	1a5h	A	65	90	TVILGRTYRVVPGEEEQKFEVEKYIV	EEEES-SBSSS--TT-EEEEEEEEEE	bxbbvbabaaxpxaaxbxbbxabbxb
1a5i_A_65	1a5i	A	65	90	KVVLGRTYRVKPGEEEQTFKVKKYIV	EEEES-SSSSS--TT-EEEEEEEEEE	bbbbvbaxaaxxxaaxbbbbxabbbb
1aut_C_65	1aut	C	65	90	LVRLGEYDLRRWEKWELDLDIKEVFV	EEEES--BTT---TT-EEEEEEEEEE	bbbxvxabaabxbaaxbxbbxabbbx
1bio_*_64	1bio	-	65	90	QVLLGAHSLSQPEPSKRLYDVLRAVP	EEEES-SBSSS--TT-EEEEEEEEEE	bbxbvbaxaaxwbaaxbxxxbabbbx
1cgh_A_64	1cgh	A	65	90	NVTLGAHNIQRRENTQQHITARRAIR	EEEES-SBTTS--TT-EEEEEEEEEE	bbbbvxaxaabxxaaxbbbxxabbxx
1ddj_A_615	1ddj	A	615	640	KVILGAHQEVNLEPHVQEIEVSRLFL	EEEES-SBSSS--TT-EEEEEEEEEE	bbbbvxNxaaxxxaaxxbbxxabbbx
1euf_A_62	1euf	A	65	90	NVTLGAHNIMERERTQQVIPVRRPIP	EEEES-SBTTS--TT-EEEEEEEEEE	bbbbvbabaabxxaaxbbbxxabwbx
1fi8_A_64	1fi8	A	66	91	QVTLGAHNIKEQEKMQQIIPVVKIIP	EEEES-SBTTS--TT-EEEEEEEEEE	bbbblbabaaxxxaaxbxbxxabxbx
1fuj_A_64	1fuj	A	65	90	NVVLGAHNVRTQEPTQQHFSVAQVFL	EEEES-SBTTS--TT-EEEEEEEEEE	bxbbvxaxaabxxaaxbbbbxabbbb
1iau_A_63	1iau	A	65	90	NVTLGAHNIKEQEPTQQFIPVKRPIP	EEEES-SBTTS--TT-EEEEEEEEEE	bxbbvxaxaabxbaaxbxbxxabwbx
1lo6_A_64	1lo6	A	64	89	QVFLGKHNLRQRESSQEQSSVVRAVI	EEEES-SBTTS--TT-EEEEEEEEEE	bbbbvxabaabxbaaxbbbxbabbbx
1mza_A_64	1mza	A	65	90	TVVLGAHSLSKNEASKQTLEIKKFIP	EEEES-SBSSS--TT-EEEEEEEEEE	bbbblbabaaxxbaaxbbbxxabbbx
1nn6_A_65	1nn6	A	67	92	TVTLGAHNITEEEDTWQKLEVIKQFR	EEEES-SBTTS--TT-EEEEEEEEEE	bbbbvxaxaabpbaaxbxbxxabxbx
1pfx_C_65	1pfx	C	65	90	TVVAGEYNTEETEPTEQRRNVIRAIP	EEEET--BTTS--TT-EEEEEEEEEE	bxbpvxIxaabxxaapbxbbxabbbx
3rp2_A_63	3rp2	A	65	90	TVILGAHDVRKRESTQQKIKVEKQII	EEEES-SBTTS--TT-EEEEEEEEEE	bbbxvbaxaabxxaaxbxbxxabbbx

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1euf_A_62	1euf	A	NAGN-ACETYL-D-GLUCOSAMINE	S - 62
1euf_A_62	1euf	A	NAGN-ACETYL-D-GLUCOSAMINE	S - 63
1euf_A_62	1euf	A	NAGN-ACETYL-D-GLUCOSAMINE	I - 64
1euf_A_62	1euf	A	NAGN-ACETYL-D-GLUCOSAMINE	N - 65
1euf_A_62	1euf	A	NAGN-ACETYL-D-GLUCOSAMINE	V - 82
1euf_A_62	1euf	A	NAGN-ACETYL-D-GLUCOSAMINE	P - 84
1iau_A_63	1iau	A	ZNZINC ION	G - 69
1iau_A_63	1iau	A	ZNZINC ION	H - 71
1iau_A_63	1iau	A	ZNZINC ION	K - 74
1iau_A_63	1iau	A	ZNZINC ION	E - 77
1iau_A_63	1iau	A	ZNZINC ION	T - 79
1iau_A_63	1iau	A	NAGN-ACETYL-D-GLUCOSAMINE	F - 82
1nn6_A_65	1nn6	A	NAGN-ACETYL-D-GLUCOSAMINE	N - 74
1nn6_A_65	1nn6	A	NAGN-ACETYL-D-GLUCOSAMINE	I - 75
1nn6_A_65	1nn6	A	NAGN-ACETYL-D-GLUCOSAMINE	T - 76
1nn6_A_65	1nn6	A	NAGN-ACETYL-D-GLUCOSAMINE	E - 77

Clusters included in this Subclass

CLUSTER: HA.11.1