ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 18.4.1

Subclass Accession number: 8058
Subclass: 18.4.1

Type: HA beta-beta hairpin
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 1.11 (>75 %)  1.11.1 (>75 %)  1.11.1.6
GO : GO:0004096 (>75 %)  GO:0004601 (>75 %)  GO:0016684 (>75 %)
SCOP : 56633 (>75 %)  56634 (>75 %)  56635 (>75 %)

Number of loops: 2

Average sequence ID (%) : 54.1 +/- 0.0
Average RMSD (Å) : 0.200 +/- 0.000

Consensus geometry

d (Å): 5

delta (°): 135-180

theta (°): 135-180

rho (°): 270-315

Consensus Sequence:	pVTpDITchXXXXhFSphGKpT
(φψ)-conformation:	bpabpaaaabapaaaabplpbb

Pattern:	[G]	[S]	[G]	[A]	[F]	[G]	[TY]	[F]	[ET]	[V]	[T]	[DH]	[D]	[I]	[T]	[DK]	[IY]	[CT]	[GR]	[AS]	[AK]	[IM]	[F]	[S]	[EK]	[IV]	[G]	[K]	[KR]	[T]	[EK]	[CM]	[FL]	[AT]	[R]	[F]	[S]
Conservation:	1.361	0.018	1.361	0.018	1.361	1.361	-1.325	1.361	-1.325	0.018	0.690	-0.653	1.361	0.018	0.690	-1.157	-1.157	-0.653	-1.493	-0.989	-1.493	-0.821	1.361	0.018	-0.653	-0.318	1.361	0.690	-0.318	0.690	-0.653	-0.653	-0.989	-1.157	0.690	1.361	0.018

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1a4e_A_73	1a4e	A	73	109	GSGAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFS	EEEEEEEEEE-S--TTT---GGGSSTT-EEEEEEEEE	bbbbxbbbbxabxaaaabaxaaaabxvxbbxbbbbxb
1e93_A_57	1e93	A	57	93	GSGAFGTFTVTHDITKYTRAKIFSEVGKKTEMFARFS	EEEEEEEEEE-S--TTT---GGGSSTT-EEEEEEEEE	bbbbxbbbbxabxaaaabapaaaabxvxbbxbbbbbb

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1a4e_A_73	1a4e	A	HEMPROTOPORPHYRIN IX CONTAINING FE	R - 107
1a4e_A_73	1a4e	A	HEMPROTOPORPHYRIN IX CONTAINING FE	F - 108
1a4e_A_73	1a4e	A	HEMPROTOPORPHYRIN IX CONTAINING FE	S - 109
1e93_A_57	1e93	A	OMTS-DIOXYMETHIONINE	R - 91
1e93_A_57	1e93	A	HEMPROTOPORPHYRIN IX CONTAINING FE	R - 91
1e93_A_57	1e93	A	HEMPROTOPORPHYRIN IX CONTAINING FE	F - 92
1e93_A_57	1e93	A	HEMPROTOPORPHYRIN IX CONTAINING FE	S - 93

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1e93_A_57	1e93	A	HEMHEM BINDING SITE FOR CHAIN A HIS A 54 IS THE DISTAL HISTIDINE TYR A 337 IS THE PROXIMAL TYROSINE	R - 91

Clusters included in this Subclass