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PDB code:

Information on SUBCLASS 3.2.5

Subclass Accession number: 8309 Subclass: 3.2.5 Type: HE alpha-beta DB: ArchDB-EC Image coordinates: Consensus coordinates:

Number of loops: 23 Average sequence ID (%) : 11.8 +/- 16.6 Average RMSD (Å) : 0.757 +/- 0.290 Consensus geometry d (Å): 9 delta (°): 90-135 theta (°): 135-180 rho (°): 315-360

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1ao0_A_401	1ao0	A	401	414	VEEIRQEIGADTLS	HHHHHHHHT-SEEE	aaaaaaaavxabbb
1az9_*_94	1az9	-	95	108	QDAAPEKLGVDRAL	HHHHHHHHT-SEEE	aaaaaaaavbabbb
1bs0_A_84	1bs0	A	90	103	EEELAEWLGYSRAL	HHHHHHHHT-SEEE	aaaaaaaavbabbb
1c4k_A_174	1c4k	A	179	192	EKHAARVYNADKTY	HHHHHHHTT-SEEE	aaaaaaaalbabbb
1ccw_A_101	1ccw	A	104	116	VEKRFKDMGYDRV.	HHHHHHHTT-SEE.	aaaaaaaagxabb.
1fit_*_52	1fit	-	66	79	GTVVEKHFHGTSLT	HHHHHHHTT-SEEE	aaaaaaaalxabbb
1g2a_A_25	1g2a	A	34	47	MFETMYAEEGIGLA	HHHHHHHTT-SEEE	aaaaaaaalbabbb
1gpj_A_29	1gpj	A	30	43	VRDIVESFGLSGSV	HHHHHHHHT-SEEE	aaaaaaaalxabbb
1gsa_*_249	1gsa	-	258	271	IGPTLKEKGLIFVG	HHHHHHHTT--EEE	aaaaaaaavxabbb
1ibj_A_133	1ibj	A	139	152	ESLLAKLDKADRAF	HHHHHHHHT-SEEE	aaaaaaaalbabbb
1iye_A_164	1iye	A	170	183	VGSEARRHGYQEGI	HHHHHHHTT-SEEE	aaaaaaaavxabbb
1iye_A_75	1iye	A	82	95	CRDVIRKNNLTSAY	HHHHHHHTT-SSEE	aaaaaaaalbabeb
1j93_A_180	1j93	A	197	210	YIRYQADSGAQAVQ	HHHHHHHTT-SEEE	aaaaaaaagxabbx
1jxh_A_155	1jxh	A	161	174	QGRALLAMGCEAVL	HHHHHHHTT-SEEE	aaaaaaaagxabbb
1k62_A_213	1k62	A	213	225	RELLRAELNFGAI.	HHHHHHHTT-SEE.	aaaaaaaalxabb.
1k8w_A_25	1k8w	A	29	42	LQKVKRIYNANRAG	HHHHHHHTT-S-EE	aaaaaaaalxabbb
1lme_A_24	1lme	A	33	46	MIETMYHYDGVGLA	HHHHHHHTT-SEEE	aaaaaaaavxabbb
1n5n_A_26	1n5n	A	35	48	MFETMYEAPGIGLA	HHHHHHHTT-SEEE	aaaaaaaawbabbb
1n8p_A_55	1n8p	A	61	74	ERAVAALENAQYGL	HHHHHHHTT-SEEE	aaaaaaaalbabbb
1qtw_A_14	1qtw	A	17	30	AAIRAAEIDATAFA	HHHHHHHTT-SEEE	aaaaaaaavxabbb
1r3f_A_25	1r3f	A	29	42	LQKVKRIYNANRAG	HHHHHHHTTBSSEE	aaaaaaaalxabbb
1rn5_A_28	1rn5	A	37	50	MFDTMRHAEGVGLA	HHHHHHHTT-SEEE	aaaaaaaavxabbb
2oat_A_120	2oat	A	124	137	EEYITKLFNYHKVL	HHHHHHHHT-SEEE	aaaaaaaavbabbb

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1c4k_A_174	1c4k	A	GTPGUANOSINE-5'-TRIPHOSPHATE	V - 176
1c4k_A_174	1c4k	A	GTPGUANOSINE-5'-TRIPHOSPHATE	E - 179
1c4k_A_174	1c4k	A	GTPGUANOSINE-5'-TRIPHOSPHATE	K - 180
1c4k_A_174	1c4k	A	GTPGUANOSINE-5'-TRIPHOSPHATE	A - 183
1c4k_A_174	1c4k	A	GTPGUANOSINE-5'-TRIPHOSPHATE	R - 184
1c4k_A_174	1c4k	A	GTPGUANOSINE-5'-TRIPHOSPHATE	D - 189
1c4k_A_174	1c4k	A	GTPGUANOSINE-5'-TRIPHOSPHATE	K - 190
1c4k_A_174	1c4k	A	GTPGUANOSINE-5'-TRIPHOSPHATE	T - 191
1c4k_A_174	1c4k	A	GTPGUANOSINE-5'-TRIPHOSPHATE	Y - 192
1c4k_A_174	1c4k	A	GTPGUANOSINE-5'-TRIPHOSPHATE	F - 193
1fit_*_52	1fit	*	MSESELENOMETHIONINE	L - 58
1fit_*_52	1fit	*	MSESELENOMETHIONINE	F - 59
1fit_*_52	1fit	*	FRUFRUCTOSE	K - 71
1fit_*_52	1fit	*	FRUFRUCTOSE	H - 72
1fit_*_52	1fit	*	FRUFRUCTOSE	F - 73
1fit_*_52	1fit	*	FRUFRUCTOSE	H - 74
1fit_*_52	1fit	*	MSESELENOMETHIONINE	F - 80
1g2a_A_25	1g2a	A	BB2ACTINONIN	E - 41
1g2a_A_25	1g2a	A	BB2ACTINONIN	E - 42
1g2a_A_25	1g2a	A	BB2ACTINONIN	G - 43
1g2a_A_25	1g2a	A	BB2ACTINONIN	I - 44
1g2a_A_25	1g2a	A	BB2ACTINONIN	G - 45
1g2a_A_25	1g2a	A	BB2ACTINONIN	L - 46
1g2a_A_25	1g2a	A	BB2ACTINONIN	A - 47
1gpj_A_29	1gpj	A	GMC(2R,3R,4S,5S)-4-AMINO-2-[6-(DIMETHYLAMINO)-9H-PURIN-9-YL]-5-(HYDROXYMETHYL)TETRAHYDRO-3-FURANOL	T - 47
1gpj_A_29	1gpj	A	GLUGLUTAMIC ACID	T - 47
1gsa_*_249	1gsa	*	ADPADENOSINE-5'-DIPHOSPHATE	D - 273
1gsa_*_249	1gsa	*	MGMAGNESIUM ION	D - 273
1gsa_*_249	1gsa	*	ADPADENOSINE-5'-DIPHOSPHATE	I - 275
1iye_A_75	1iye	A	PGU4-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-BUTYRIC ACID	Y - 95
1iye_A_75	1iye	A	PGU4-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-BUTYRIC ACID	R - 97
1iye_A_164	1iye	A	PGU4-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-BUTYRIC ACID	Y - 164
1iye_A_164	1iye	A	PGU4-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-BUTYRIC ACID	S - 167
1lme_A_24	1lme	A	OCSCYSTEINESULFONIC ACID	G - 44
1n5n_A_26	1n5n	A	GOLGLYCEROL	M - 39
1n5n_A_26	1n5n	A	GOLGLYCEROL	P - 43
1n5n_A_26	1n5n	A	GOLGLYCEROL	G - 44
1n5n_A_26	1n5n	A	GOLGLYCEROL	I - 45
1n5n_A_26	1n5n	A	ZNZINC ION	G - 46
1n5n_A_26	1n5n	A	GOLGLYCEROL	G - 46
1n5n_A_26	1n5n	A	GOLGLYCEROL	L - 47

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1gpj_A_29	1gpj	A	ACTRECOGNITION AND ACTIVE SITE, HERE OCCUPIED BY THE INHIBITOR GLUTAMYCIN	T - 47

Clusters included in this Subclass

CLUSTER: HE.4.24

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