ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 22.1.1

Subclass Accession number: 857
Subclass: 22.1.1

Type: HA beta-beta hairpin
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 4.2 (>50 %)  4.2.2 (>50 %)
GO : GO:0016829 (>75 %)  GO:0016835 (>50 %)  GO:0016837 (>50 %)
SCOP : 49993 (>75 %)  50006 (>75 %)  74650 (>75 %)

Number of loops: 3

Average sequence ID (%) : 42.9 +/- 12.2
Average RMSD (Å) : 0.433 +/- 0.115

Consensus geometry

d (Å): 5

delta (°): 90-135

theta (°): 135-180

rho (°): 315-360

Consensus Sequence:	hSpRXXppEphNpENXXGXYXXXGhX
(φψ)-conformation:	bbaabpabbbbllblaaaaaaaalpb

Pattern:	[AGS]	[FL]	[GN]	[LV]	[ARS]	[LM]	[FVY]	[S]	[KST]	[R]	[IT]	x	[NRS]	[SY]	[E]	[HS]	[GIM]	[N]	[KS]	[E]	[N]	[GKL]	x	[G]	[RW]	[Y]	[LT]	[GS]	[AD]	[G]	[AM]	[FT]	[NY]	[IL]	[QY]
Conservation:	-0.645	-0.029	0.100	-0.210	-0.955	0.150	-0.459	0.597	-0.769	1.156	-0.507	-1.452	-0.707	-0.422	1.156	-0.399	-1.452	1.715	-0.243	1.156	1.715	-1.701	-0.819	1.715	0.194	2.274	-0.550	-0.295	-0.556	1.715	-0.632	-0.595	-0.240	0.059	-0.062

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1cb8_A_356	1cb8	A	357	391	SFNVRMVSKRTRRSESGNKENLLGRYLSDGATNIQ	EEEEE---TTSB----BTTBSTT-TTTTSSEEEEE	bbbbbbbbaabbxpxbblvblaaaaaaaavxbxbb
1j0m_A_407	1j0m	A	407	441	ALGLALYSTRISSYESINSENGRGWYTGAGATYLY	EEEEE---SSSBS----TTB-TT-TTTTSSEEEEE	bbbbbbbbaabxabbbbllblaaaaaaaavxbbbb
1n7o_A_562	1n7o	A	563	597	GFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLY	EEEEE---TTS-S---BTTB-TT-TTTTSS-EEEE	bbbbbbbbaabxabbbblvbvaaaaaaaavxbbbb

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1cb8_A_356	1cb8	A	GOLGLYCEROL	E - 371
1cb8_A_356	1cb8	A	GOLGLYCEROL	E - 376
1cb8_A_356	1cb8	A	GCUD-GLUCURONIC ACID	R - 381

Clusters included in this Subclass

CLUSTER: HA.25.0