ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 10.4.1

Subclass Accession number: 8747
Subclass: 10.4.1

Type: HE alpha-beta
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Number of loops: 4

Average sequence ID (%) : 49.5 +/- 19.5
Average RMSD (Å) : 0.400 +/- 0.000

Consensus geometry

d (Å): 27

delta (°): 0-45

theta (°): 90-135

rho (°): 135-180

Consensus Sequence:	pEpIPERXhHApGp
(φψ)-conformation:	aapbpppablapbb

Pattern:	[FTVY]	x	[L]	x	[DEQ]	[KST]	[HIL]	[AQT]	[HR]	[F]	[DN]	[HR]	[EM]	[NR]	[I]	[P]	[EQ]	[R]	x	[PV]	[H]	[A]	[HKR]	[G]	[ST]	[AG]	[AV]	[FHK]	[G]	[EY]	[F]	[EQT]	[APV]
Conservation:	-1.021	-1.297	0.451	-1.024	-0.130	-0.740	-1.018	-0.937	0.461	1.432	0.208	0.006	-0.588	-0.171	0.451	1.923	0.279	0.941	-1.481	-0.682	2.413	0.451	-0.380	1.432	-0.156	-0.027	-0.437	-1.023	1.432	-0.525	1.432	-0.641	-1.035

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1a4e_A_50	1a4e	A	50	82	YNLIDSLAHFNRENIPQRNPHAHGSGAFGYFEV	HHHHHHHHHHTT------SS--SEEEEEEEEEE	aaaaaaaaaaaaaxbpxpbwvaxbbbbxbbbbx
1gwe_A_41	1gwe	A	41	73	THLLETHQHFNRMNIPERRPHAKGSGAFGEFEV	HHHHHHHHHHTT------SS--SEEEEEEEEEE	aaaaaaaaaaaaaxbpxpbwvaxbbbbxbbbbx
1m7s_A_58	1m7s	A	58	90	VQLLQKLQRFDRERIPERVVHARGTGVKGEFTA	HHHHHHHHHHTT------SS--SEEEEEEEEEE	aaaaaaaaaaaaaxbxxxablaxbbbbbbbbbx
1p80_A_108	1p80	A	108	140	FILREKITHFDHERIPERIVHARGSAAHGYFQP	HHHHHHHHHHHT------SS--SEEEEEEEEEE	aaaaaaaaaaaaaxbpxpabvaxbbbbxbbbbx

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1a4e_A_50	1a4e	A	HEMPROTOPORPHYRIN IX CONTAINING FE	L - 56
1a4e_A_50	1a4e	A	HEMPROTOPORPHYRIN IX CONTAINING FE	F - 59
1a4e_A_50	1a4e	A	HEMPROTOPORPHYRIN IX CONTAINING FE	N - 60
1a4e_A_50	1a4e	A	HEMPROTOPORPHYRIN IX CONTAINING FE	Q - 66
1a4e_A_50	1a4e	A	HEMPROTOPORPHYRIN IX CONTAINING FE	R - 67
1a4e_A_50	1a4e	A	HEMPROTOPORPHYRIN IX CONTAINING FE	N - 68
1a4e_A_50	1a4e	A	HEMPROTOPORPHYRIN IX CONTAINING FE	P - 69
1a4e_A_50	1a4e	A	AZIAZIDE ION	P - 69
1a4e_A_50	1a4e	A	HEMPROTOPORPHYRIN IX CONTAINING FE	H - 70
1a4e_A_50	1a4e	A	AZIAZIDE ION	H - 70
1gwe_A_41	1gwe	A	HEMPROTOPORPHYRIN IX CONTAINING FE	E - 57
1gwe_A_41	1gwe	A	HEMPROTOPORPHYRIN IX CONTAINING FE	R - 58
1gwe_A_41	1gwe	A	HEMPROTOPORPHYRIN IX CONTAINING FE	R - 59
1gwe_A_41	1gwe	A	HEMPROTOPORPHYRIN IX CONTAINING FE	P - 60
1gwe_A_41	1gwe	A	HEMPROTOPORPHYRIN IX CONTAINING FE	H - 61
1m7s_A_58	1m7s	A	HEMPROTOPORPHYRIN IX CONTAINING FE	L - 64
1m7s_A_58	1m7s	A	HEMPROTOPORPHYRIN IX CONTAINING FE	F - 67
1m7s_A_58	1m7s	A	HEMPROTOPORPHYRIN IX CONTAINING FE	D - 68
1m7s_A_58	1m7s	A	HEMPROTOPORPHYRIN IX CONTAINING FE	E - 74
1m7s_A_58	1m7s	A	HEMPROTOPORPHYRIN IX CONTAINING FE	R - 75
1m7s_A_58	1m7s	A	HEMPROTOPORPHYRIN IX CONTAINING FE	V - 76
1m7s_A_58	1m7s	A	HEMPROTOPORPHYRIN IX CONTAINING FE	V - 77
1m7s_A_58	1m7s	A	HEMPROTOPORPHYRIN IX CONTAINING FE	H - 78
1p80_A_108	1p80	A	HEMPROTOPORPHYRIN IX CONTAINING FE	I - 114
1p80_A_108	1p80	A	HEMPROTOPORPHYRIN IX CONTAINING FE	F - 117
1p80_A_108	1p80	A	HEMPROTOPORPHYRIN IX CONTAINING FE	D - 118
1p80_A_108	1p80	A	HEMPROTOPORPHYRIN IX CONTAINING FE	E - 124
1p80_A_108	1p80	A	HEMPROTOPORPHYRIN IX CONTAINING FE	R - 125
1p80_A_108	1p80	A	HEMPROTOPORPHYRIN IX CONTAINING FE	I - 126
1p80_A_108	1p80	A	HEMPROTOPORPHYRIN IX CONTAINING FE	V - 127
1p80_A_108	1p80	A	HEMPROTOPORPHYRIN IX CONTAINING FE	H - 128

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1gwe_A_41	1gwe	A	AC1HEM BINDING SITE FOR CHAIN A	H - 47
1gwe_A_41	1gwe	A	AC1HEM BINDING SITE FOR CHAIN A	N - 51
1gwe_A_41	1gwe	A	AC1HEM BINDING SITE FOR CHAIN A	R - 58
1gwe_A_41	1gwe	A	AC1HEM BINDING SITE FOR CHAIN A	R - 59
1gwe_A_41	1gwe	A	AC1HEM BINDING SITE FOR CHAIN A	P - 60
1gwe_A_41	1gwe	A	AC1HEM BINDING SITE FOR CHAIN A	H - 61

Clusters included in this Subclass

CLUSTER: HE.12.2