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Information on SUBCLASS 24.1.1
Subclass Accession number: 8781
Subclass: 24.1.1 PSSM
Type: HE alpha-beta
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 3.5 (>75 %)  3.5.2 (>75 %)  3.5.2.6
GO : GO:0008800 (>75 %)  GO:0016810 (>75 %)  GO:0016812 (>75 %)  
SCOP : 56600 (>75 %)  56601 (>75 %)  56602 (>75 %)  
 Number of loops: 8

Average sequence ID (%) : 45.9 +/- 26.8
Average RMSD (Å) : 0.487 +/- 0.083

Consensus geometry
d (Å): 15 delta (°): 90-135 theta (°): 0-45 rho (°): 135-180
Consensus Sequence: phGDpXTphpRhEhpLNphXhGpXpDTp
(φψ)-conformation: aagpaapbbabppwaaaalppgpaplbb
Pattern: [AEK][AGKS][LMV][KT][ADKQR][EFR][ALMV][KR][EKQS][ILV][GN][D][ekr]x[FTY][NR][LP][dv][R][fkwy][DE][ILPV][DE][L][NQ][ESTY][AGVY]x[hp][GK][DERS]x[KQRT][D][T][ST]
Conservation:-0.518-0.7980.099-0.076-0.747-0.893-0.5090.939-0.3900.3370.9132.261-0.667-1.336-0.4000.317-0.655-0.3401.664-0.7431.039-0.8000.9191.0670.905-0.942-1.084-1.343-0.4990.280-0.475-1.408-0.3422.2611.6640.299
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1alq_*_1451alq   -146181KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSHHHHHHHHHTT--S------TTGGG---TT--TTEEaaaaaaaaaavxaapbxabxxwaaaxxbaabaxlbb
1bsg_*_1461bsg   -146181AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTHHHHHHHHHTT-SS----S-TTGGG---TT--TTEEaaaaaaaaaavxaapbbabxxwaaaalxaaxaxlbb
1bue_A_1441bue   A146181EGMTKFMRSIGDEDFRLDRWELDLNTAIPGDERDTSHHHHHHHHHTT-SS-B--S-TTGGG---TT--TTEEaaaaaaaaaavxaapbbabxxwaaaalxpvxaxlbb
1g6a_A_1441g6a   A146181KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTHHHHHHHHHTT-SS-B----TTGGG---TT--TTEEaaaaaaaaaagxaapbbabbxwaaaavxpvxaxlbb
1ghp_A_1451ghp   A146181KKVKQRLKELGDKVTNPVRYDIELQYYSPKSKKDTSHHHHHHHHHTT--S-B--S-TTGGG---TT--TTEEaaaaaaaaaavxaapbxabxxwaaaxxbaabaplbb
1hzo_A_1451hzo   A146181AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTHHHHHHHHHTT-SS------TTGGG---TT--TTEEaaaaaaaaaavbaapbbabbxwaaaalxxvbaxlbb
1i2s_A_1451i2s   A146181ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSHHHHHHHHHTT--S------TTGGG---TT--TTEEaaaaaaaaaagxaapbxabxxwaaaxbxpgxaxlbb
1mfo_A_1451mfo   A146181AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSHHHHHHHHHTT-SS----S-TTGGG---TT--TTEEaaaaaaaaaavxaaxbbabbxwaaaalpaaxaxlbb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1ghp_A_1451ghp   A     PNMOPEN FORM - PENICILLIN G D - 166
1ghp_A_1451ghp   A     PNMOPEN FORM - PENICILLIN G I - 167
1ghp_A_1451ghp   A     PNMOPEN FORM - PENICILLIN G Q - 170
1i2s_A_1451i2s   A     CITCITRIC ACID E - 166
1i2s_A_1451i2s   A     CITCITRIC ACID N - 170
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1mfo_A_1451mfo   A ACTACTIVE SERINE 70E - 166

Clusters included in this Subclass
CLUSTER: HE.25.0