ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 1.1.22

Subclass Accession number: 8804
Subclass: 1.1.22

Type: HH alpha-alpha
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Number of loops: 4

Average sequence ID (%) : 63.1 +/- 11.9
Average RMSD (Å) : 0.350 +/- 0.100

Consensus geometry

d (Å): 5

delta (°): 45-90

theta (°): 135-180

rho (°): 90-135

Consensus Sequence:	CYSXD
(φψ)-conformation:	aapaa

Pattern:	[E]	x	[E]	[KR]	x	[R]	[V]	[D]	[IV]	[IL]	[E]	[N]	[HQ]	[ALTV]	[M]	[D]	x	[HR]	[LMT]	[AQ]	[FL]	[AGI]	[MR]	[ILV]	[C]	[Y]	[NS]	[PS]	[DE]	[FH]	[E]	[KR]	[KL]	[K]	[P]	[AEKQ]	[Y]	[L]	[E]	[EGQ]	[L]	[P]	[EG]	[KQ]	[LM]	[KR]	x	[FLY]	[S]	[EMR]	[F]	[L]
Conservation:	0.690	-1.057	0.690	-0.022	-1.412	0.690	0.185	1.195	-0.067	-0.291	0.690	1.195	-0.281	-1.360	0.690	1.195	-1.739	-0.280	-0.974	-0.818	-0.621	-1.522	-0.823	-0.513	2.709	1.700	-0.382	-0.426	0.181	-0.326	0.690	-0.022	-1.167	0.690	1.700	-1.171	1.700	0.185	0.690	-1.108	0.185	1.700	-0.941	-0.263	-0.217	-0.027	-1.194	-0.581	0.185	-1.312	1.195	0.185

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1b4p_A_90	1b4p	A	90	141	EEERIRVDVLENQAMDTRLQLAMVCYSPDFERKKPEYLEGLPEKMKLYSEFL	HHHHHHHHHHHHHHHHHHHHHHHHHH-TTHHHHHHHHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaaaaaaaaaaaxaaaaaaaaaaaaaaaaaaaaaaaaa
1gsu_A_90	1gsu	A	90	141	EVEKQRVDVLENHLMDLRMAFARLCYSPDFEKLKPAYLEQLPGKLRQLSRFL	HHHHHHHHHHHHHHHHHHHHHHHHHHSTTHHHHHHHHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaaaaaaaaaaaxaaaaaaaaaaaaaaaaaaaaaaaaa
1gtu_A_90	1gtu	A	90	141	EEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFL	HHHHHHHHHHHHHHHHHHHHHHHHHHSTTHHHHHHHHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaaaaaaaaaaaxaaaaaaaaaaaaaaaaaaaaaaaaa
3gtu_B_94	3gtu	B	94	145	EEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFL	HHHHHHHHHHHHHHHHHHHHHHHHHHSTTHHHHHHHHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaaaaaaaaaaapaaaaaaaaaaaaaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1b4p_A_90	1b4p	A	GPS(9S,10S)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE	M - 104
1b4p_A_90	1b4p	A	GPS(9S,10S)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE	R - 107
1b4p_A_90	1b4p	A	GPS(9S,10S)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE	L - 108
1b4p_A_90	1b4p	A	GPS(9S,10S)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE	A - 111
1b4p_A_90	1b4p	A	GPS(9S,10S)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE	Y - 115
1gsu_A_90	1gsu	A	GTXS-HEXYLGLUTATHIONE	N - 101
1gsu_A_90	1gsu	A	GTXS-HEXYLGLUTATHIONE	M - 104
1gsu_A_90	1gsu	A	GTXS-HEXYLGLUTATHIONE	D - 105
1gsu_A_90	1gsu	A	GTXS-HEXYLGLUTATHIONE	M - 108
1gsu_A_90	1gsu	A	GTXS-HEXYLGLUTATHIONE	A - 111
1gsu_A_90	1gsu	A	GTXS-HEXYLGLUTATHIONE	Y - 115

Clusters included in this Subclass