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Information on SUBCLASS 4.1.1
Subclass Accession number: 9031
Subclass: 4.1.1 PSSM
Type: HH alpha-alpha
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 45

Average sequence ID (%) : 16.3 +/- 16.9
Average RMSD (Å) : 0.678 +/- 0.280

Consensus geometry
d (Å): 11 delta (°): 90-135 theta (°): 135-180 rho (°): 180-225
Consensus Sequence: XXcXhpXX
(φψ)-conformation: aalabpaa
Pattern: xx[afilvy]xx[egknqrs]x[acfiklmtv][dhkrstwy]x[adekqrst][adekqst][acfgiklmtv]
Conservation:-0.686-0.8480.178-0.645-0.5672.533-0.950-0.0010.290-0.9500.5041.215-0.073
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1afr_A_1311afr   A153165YLYLSGRVDMRQIHHHHH-SS-HHHHaaaaavabxaaaa
1b7g_O_3041b7g   O312324IRASMKLMSAEDSHHHHTT-S-HHHHaaaaalabxaaaa
1d2n_A_6811d2n   A687699ALELLGNFKDKERHHHHHT-S-HHHHaaaaalaxxaaaa
1dcu_A_211dcu   A2739QQEQKGIIDAELTHHHHTTSS-HHHHaaaaavabxaaaa
1dj0_A_2031dj0   A212224MEVGAHNQPESWIHHHHTTSS-TTHHaaaaavabxaaaa
1dnp_A_2381dnp   A239251ASLATGGLSPRQCHHHHHTSS-HHHHaaaaavabbaaaa
1e9y_A_321e9y   A4557EEARAGKKTAAELHHHHHT-S-HHHHaaaaavapxaaaa
1ex7_A_1251ex7   A131143RLEGRGTETEESIHHHHH--S-HHHHaaaaavabxaaaa
1f0y_A_2071f0y   A220232RLYERGDASKEDIHHHHTTSS-HHHHaaaaavabxaaaa
1fur_A_4351fur   A438450AALALGYLSEAEFHHHHTTSS-HHHHaaaaavabbaaaa
1h16_A_2801h16   A289301RDLKAGKITEQEAHHHHTTSS-HHHHaaaaavabxaaaa
1h5y_A_2281h5y   A228240SLFHFRVLSIAQVHHHHTTSS-HHHHaaaaalabxaaaa
1h7n_A_2901h7n   A298310AAAEKGVVDLKTIHHHHTTSS-HHHHaaaaavabxaaaa
1i58_A_4561i58   A462474KAIEKGLIDESKAHHHHTTSS-HHHHaaaaavabbaaaa
1i7d_A_5691i7d   A579591TQISEKQCRYQDFHHHHTTSS-HHHHaaaaalabxaaaa
1ikt_A_761ikt   A8092MEVVLGKLDPQKAHHHHTTSS-HHHHaaaaavabxaaaa
1ire_B_281ire   B3951ATFRAGFMGLDEFHHHHTTS--HHHHaaaaavabbaaaa
1ire_B_681ire   B7991HGVRTGKIDLEELHHHHTT-S-HHHHaaaaavabxaaaa
1is2_A_5711is2   A573585DFLEGSIITGAQLHHHHTTSS-HHHHaaaaalabxaaaa
1j1u_A_2701j1u   A275287SLFKNKELHPMDLHHHHTTSS-HHHHaaaaavabxaaaa
1j5s_A_4031j5s   A421433EMVEKGQIPIKEAHHHHTTSS-HHHHaaaaavabpaaaa
1jvs_A_3281jvs   A343355AAFLAQQIRFTDIHHHHTTSS-TTHHaaaaalabxaaaa
1k62_A_351k62   A4860GLEKAGLLTKAEMHHHHTTSS-HHHHaaaaavabxaaaa
1k7w_A_371k7w   A5062ALEKAGILTKTELHHHHTTSS-HHHHaaaaavabxaaaa
1kbl_A_3431kbl   A352364DLVDEGMITEEEAHHHHTTSS-HHHHaaaaavabxaaaa
1kut_A_1271kut   A129141HLEILGIATKKQAHHHHTTS--HHHHaaaaavabbaaaa
1l6s_A_2721l6s   A280292FAALAGAIDEEKVHHHHTTSS-HHHHaaaaavabxaaaa
1l8a_A_1441l8a   A150162RAFLEGRLTQEQLHHHHTTSS-HHHHaaaaavabxaaaa
1lvg_A_1271lvg   A133145RLRLRNTETEESLHHHHHT-S-HHHHaaaaalabxaaaa
1m5y_A_3001m5y   A312324ADIKSGKTTFAAAHHHHTTSS-HHHHaaaaaUabxaaaa
1mla_*_931mla   -98110ALVCAGVIDFADAHHHHTTSS-HHHHaaaaavabxaaaa
1n8i_A_6341n8i   A646658NWLRHGVITSADVHHHHTTSS-HHHHaaaaavabbaaaa
1nfg_A_3431nfg   A349361QGVNEGRISLTQFHHHHTTSS-HHHHaaaaavabxaaaa
1ols_A_3151ols   A322334YLLSQGWWDEEQEHHHHHT---HHHHaaaaavabbaaaa
1p7t_A_6321p7t   A644656NWLRHGILTKEQVHHHHTTSS-HHHHaaaaavabbaaaa
1pin_A_821pin   A94106QKIKSGEEDFESLHHHHHTSS-HHHHaaaaavabxaaaa
1pv8_A_2791pv8   A287299HGAQAGAFDLKAAHHHHTTSS-HHHHaaaaavabxaaaa
1qi9_A_4651qi9   A479491GRQMLGIHYRFDGHHHHTTS--HHHHaaaaagabbaaaa
1qs0_A_3351qs0   A342354HLIKIGHWSEEEHHHHHTTS--HHHHaaaaavabbaaaa
1vfr_A_941vfr   A103115KAVADKRITEEQKHHHHTTSS-HHHHaaaaavabxaaaa
1vns_*_4791vns   -489501SRIFLGVHWRFDAHHHHTTSS-HHHHaaaaavabxaaaa
2ahj_B_352ahj   B4355GVAELGAFSVDEVHHHTS----HHHHaaaaalabbaaaa
2ahj_B_722ahj   B8395LMVEKGILTQDELHHHHTTSS-HHHHaaaaavabbaaaa
2fok_A_5482fok   A556568EMIKAGTLTLEEVHHHHHTS--HHHHaaaaavabbaaaa
3ygs_P_273ygs   P2941VLLSRELFRPHMIHHHHTTSS-HHHHaaaaalabxaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1afr_A_1311afr   A     FE2FE (II) ION W - 139
1afr_A_1311afr   A     FE2FE (II) ION E - 143
1afr_A_1311afr   A     FE2FE (II) ION H - 146
1d2n_A_6811d2n   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER L - 691
1d2n_A_6811d2n   A     GOLGLYCEROL D - 696
1d2n_A_6811d2n   A     GOLGLYCEROL K - 697
1d2n_A_6811d2n   A     GOLGLYCEROL E - 698
1d2n_A_6811d2n   A     GOLGLYCEROL T - 700
1dnp_A_2381dnp   A     FADFLAVIN-ADENINE DINUCLEOTIDE S - 238
1dnp_A_2381dnp   A     FADFLAVIN-ADENINE DINUCLEOTIDE A - 239
1dnp_A_2381dnp   A     FADFLAVIN-ADENINE DINUCLEOTIDE L - 241
1dnp_A_2381dnp   A     FADFLAVIN-ADENINE DINUCLEOTIDE A - 242
1ex7_A_1251ex7   A     5GPGUANOSINE-5'-MONOPHOSPHATE R - 146
1f0y_A_2071f0y   A     CAAACETOACETYL-COENZYME A V - 207
1f0y_A_2071f0y   A     CAAACETOACETYL-COENZYME A N - 208
1f0y_A_2071f0y   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE N - 208
1f0y_A_2071f0y   A     CAAACETOACETYL-COENZYME A L - 211
1f0y_A_2071f0y   A     CAAACETOACETYL-COENZYME A V - 212
1f0y_A_2071f0y   A     CAAACETOACETYL-COENZYME A G - 239
1f0y_A_2071f0y   A     CAAACETOACETYL-COENZYME A A - 240
1h5y_A_2281h5y   A     PO4PHOSPHATE ION S - 228
1h5y_A_2281h5y   A     PO4PHOSPHATE ION L - 229
1h7n_A_2901h7n   A     SHFLAEVULINIC ACID S - 290
1h7n_A_2901h7n   A     SHFLAEVULINIC ACID G - 291
1i58_A_4561i58   A     ACTACETATE ION K - 456
1i58_A_4561i58   A     ACTACETATE ION K - 458
1i58_A_4561i58   A     ACPPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER K - 458
1i58_A_4561i58   A     ACTACETATE ION I - 459
1i58_A_4561i58   A     ACTACETATE ION K - 462
1ikt_A_761ikt   A     OXNOXTOXYNOL-10 F - 79
1ikt_A_761ikt   A     OXNOXTOXYNOL-10 V - 82
1ikt_A_761ikt   A     OXNOXTOXYNOL-10 V - 83
1ikt_A_761ikt   A     OXNOXTOXYNOL-10 P - 89
1ikt_A_761ikt   A     OXNOXTOXYNOL-10 Q - 90
1ikt_A_761ikt   A     OXNOXTOXYNOL-10 F - 93
1ikt_A_761ikt   A     OXNOXTOXYNOL-10 F - 94
1ire_B_281ire   B     CEAS-HYDROXY-CYSTEINE L - 48
1ire_B_281ire   B     CSD3-SULFINOALANINE F - 51
1ire_B_281ire   B     CSD3-SULFINOALANINE R - 52
1ire_B_281ire   B     CEAS-HYDROXY-CYSTEINE R - 52
1ire_B_281ire   B     COCOBALT (II) ION R - 52
1ire_B_281ire   B     CSD3-SULFINOALANINE E - 56
1ire_B_681ire   B     CSD3-SULFINOALANINE Y - 68
1jvs_A_3281jvs   A     MSESELENOMETHIONINE A - 329
1jvs_A_3281jvs   A     MSESELENOMETHIONINE A - 330
1jvs_A_3281jvs   A     MSESELENOMETHIONINE A - 333
1jvs_A_3281jvs   A     MSESELENOMETHIONINE L - 334
1jvs_A_3281jvs   A     MSESELENOMETHIONINE N - 335
1jvs_A_3281jvs   A     MSESELENOMETHIONINE N - 338
1jvs_A_3281jvs   A     MSESELENOMETHIONINE F - 345
1jvs_A_3281jvs   A     MSESELENOMETHIONINE Q - 349
1jvs_A_3281jvs   A     MSESELENOMETHIONINE R - 351
1jvs_A_3281jvs   A     MSESELENOMETHIONINE F - 352
1jvs_A_3281jvs   A     MSESELENOMETHIONINE I - 355
1jvs_A_3281jvs   A     MSESELENOMETHIONINE N - 359
1jvs_A_3281jvs   A     MSESELENOMETHIONINE S - 361
1jvs_A_3281jvs   A     MSESELENOMETHIONINE V - 362
1jvs_A_3281jvs   A     MSESELENOMETHIONINE L - 363
1jvs_A_3281jvs   A     MSESELENOMETHIONINE E - 364
1kut_A_1271kut   A     MSESELENOMETHIONINE H - 129
1kut_A_1271kut   A     MSESELENOMETHIONINE L - 130
1kut_A_1271kut   A     MSESELENOMETHIONINE I - 135
1kut_A_1271kut   A     MSESELENOMETHIONINE A - 136
1kut_A_1271kut   A     MSESELENOMETHIONINE T - 137
1kut_A_1271kut   A     MSESELENOMETHIONINE K - 139
1kut_A_1271kut   A     MSESELENOMETHIONINE Q - 140
1kut_A_1271kut   A     MSESELENOMETHIONINE A - 141
1kut_A_1271kut   A     MSESELENOMETHIONINE E - 142
1l6s_A_2721l6s   A     DSB4,7-DIOXOSEBACIC ACID S - 272
1l6s_A_2721l6s   A     DSB4,7-DIOXOSEBACIC ACID G - 273
1lvg_A_1271lvg   A     ADPADENOSINE-5'-DIPHOSPHATE R - 133
1lvg_A_1271lvg   A     ADPADENOSINE-5'-DIPHOSPHATE L - 134
1lvg_A_1271lvg   A     ADPADENOSINE-5'-DIPHOSPHATE L - 136
1lvg_A_1271lvg   A     ADPADENOSINE-5'-DIPHOSPHATE R - 137
1lvg_A_1271lvg   A     5GPGUANOSINE-5'-MONOPHOSPHATE R - 137
1lvg_A_1271lvg   A     5GPGUANOSINE-5'-MONOPHOSPHATE E - 140
1lvg_A_1271lvg   A     ADPADENOSINE-5'-DIPHOSPHATE R - 148
1lvg_A_1271lvg   A     5GPGUANOSINE-5'-MONOPHOSPHATE R - 148
1n8i_A_6341n8i   A     MGMAGNESIUM ION A - 635
1n8i_A_6341n8i   A     GLVGLYOXYLIC ACID A - 635
1p7t_A_6321p7t   A     MGMAGNESIUM ION A - 633
1p7t_A_6321p7t   A     ACOACETYL COENZYME *A A - 633
1p7t_A_6321p7t   A     PYRPYRUVIC ACID A - 633
1pin_A_821pin   A     1PG2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL N - 90
1pin_A_821pin   A     1PG2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL I - 96
1pin_A_821pin   A     1PG2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL K - 97
1pin_A_821pin   A     1PG2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL F - 103
1pin_A_821pin   A     1PG2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL E - 104
1pv8_A_2791pv8   A     PB13-(2-AMINOETHYL)-4-(AMINOMETHYL)HEPTANEDIOIC ACID S - 279
1pv8_A_2791pv8   A     PB13-(2-AMINOETHYL)-4-(AMINOMETHYL)HEPTANEDIOIC ACID G - 280
1qi9_A_4651qi9   A     VO4VANADATE ION R - 480
1qi9_A_4651qi9   A     VO4VANADATE ION I - 485
1qi9_A_4651qi9   A     VO4VANADATE ION H - 486
1qs0_A_3351qs0   A     MSESELENOMETHIONINE P - 335
1qs0_A_3351qs0   A     MSESELENOMETHIONINE I - 336
1qs0_A_3351qs0   A     MSESELENOMETHIONINE R - 338
1qs0_A_3351qs0   A     MSESELENOMETHIONINE L - 339
1qs0_A_3351qs0   A     MSESELENOMETHIONINE K - 340
1qs0_A_3351qs0   A     MSESELENOMETHIONINE Q - 341
1qs0_A_3351qs0   A     MSESELENOMETHIONINE L - 343
1qs0_A_3351qs0   A     MSESELENOMETHIONINE W - 349
1qs0_A_3351qs0   A     MSESELENOMETHIONINE H - 354
1qs0_A_3351qs0   A     MSESELENOMETHIONINE T - 357
1qs0_A_3351qs0   A     MSESELENOMETHIONINE F - 361
1qs0_A_3351qs0   A     MSESELENOMETHIONINE V - 365
1qs0_A_3351qs0   A     MSESELENOMETHIONINE Q - 369
1vfr_A_941vfr   A     FMNFLAVIN MONONUCLEOTIDE R - 109
2ahj_B_352ahj   B     NONITROGEN OXIDE Y - 37
2ahj_B_352ahj   B     DIO1,4-DIETHYLENE DIOXIDE Y - 37
2ahj_B_352ahj   B     DIO1,4-DIETHYLENE DIOXIDE M - 40
2ahj_B_352ahj   B     DIO1,4-DIETHYLENE DIOXIDE V - 52
2ahj_B_352ahj   B     DIO1,4-DIETHYLENE DIOXIDE V - 55
2ahj_B_352ahj   B     CSD3-SULFINOALANINE R - 56
2ahj_B_352ahj   B     CEAS-HYDROXY-CYSTEINE R - 56
2ahj_B_352ahj   B     FEFE (III) ION R - 56
2ahj_B_352ahj   B     NONITROGEN OXIDE R - 56
2ahj_B_352ahj   B     DIO1,4-DIETHYLENE DIOXIDE R - 56
2ahj_B_722ahj   B     CSD3-SULFINOALANINE Y - 72
2ahj_B_722ahj   B     NONITROGEN OXIDE Y - 72
2ahj_B_722ahj   B     DIO1,4-DIETHYLENE DIOXIDE Y - 72
2ahj_B_722ahj   B     CSD3-SULFINOALANINE R - 75
2ahj_B_722ahj   B     CSD3-SULFINOALANINE Y - 76
2ahj_B_722ahj   B     FEFE (III) ION Y - 76
2ahj_B_722ahj   B     NONITROGEN OXIDE Y - 76
2ahj_B_722ahj   B     DIO1,4-DIETHYLENE DIOXIDE Y - 76
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1h7n_A_2901h7n   A AC1SHF BINDING SITE FOR CHAIN AS - 290

Clusters included in this Subclass
CLUSTER: HH.3.145
CLUSTER: HH.4.35
CLUSTER: HH.4.36
CLUSTER: HH.4.9
CLUSTER: HH.5.104
CLUSTER: HH.5.13
CLUSTER: HH.5.184
CLUSTER: HH.5.8
CLUSTER: HH.6.2
CLUSTER: HH.6.59
CLUSTER: HH.6.61
CLUSTER: HH.6.62